Reviewed, UniProtKB/Swiss-Prot P97323 (F16P3_MOUSE)

Names and origin

Protein names

Recommended name:
    Fructose-1,6-bisphosphatase isozyme 3
      Short name=FBPase 3
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase 3

Gene names

Name:

Fbp3

Organism

Mus musculus (Mouse)

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	94 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.
Pathway	Carbohydrate biosynthesis; gluconeogenesis.
Sequence similarities	Belongs to the FBPase class 1 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Gluconeogenesis
Molecular function	Hydrolase
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – ›94	›94	Fructose-1,6-bisphosphatase isozyme 3		PRO_0000200508
Experimental info
	Non-terminal residue	1	1
	Non-terminal residue	94	1

Sequences

	Sequence		Length	Mass (Da)
	P97323-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: CB8987281DB29944	FASTA	94	10,459
	10 20 30 40 50 60 LQPGRDLVAA GYALYGSATM LVLAMDCGVN CFMLDPSIGE FIMVERDGKM KKKGNIYSLN 70 80 90 EGYAKDFNPA ILEYHQRQKF HEDGTAPYGT RYVG

References

[1]	"Various fructose-1,6-bisphosphatase mRNAs in mouse brain, liver, kidney and heart." Cloix J.F., Beaulieu E., Hevor T.K. NeuroReport 8:617-622(1997) [PubMed: 9106734] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: C57BL/6J.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Y11067 mRNA. Translation: CAA71946.1.
IPI	IPI00123932.
UniGene	Mm.423078
3D structure databases
HSSP	HSSP built from PDB template 1FTA based on UniProtKB P09467.
SMR	P97323. Positions 1-94.
ModBase	Search...
Proteomic databases
PRIDE	P97323.
Organism-specific databases
MGI	MGI:1330236. Fbp3.
Phylogenomic databases
HOVERGEN	P97323.
Enzyme and pathway databases
BRENDA	3.1.3.11. 244.
Gene expression databases
Genevestigator	P97323.
Family and domain databases
InterPro	IPR000146. Fructose_bisphosphatase. IPR020548. Fructose_bisphosphatase_AS. [Graphical view]
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PRINTS	PR00115. F16BPHPHTASE.
ProDom	PD001491. In_FB_phphtase. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00124. FBPASE. Partial match. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

F16P3_MOUSE

Accession

Primary (citable) accession number: P97323

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	May 1, 1997
Last modified:	October 13, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)