Csrp1

Functionⁱ

Could play a role in neuronal development.By similarity

GO - Molecular functionⁱ

metal ion binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

actin cytoskeleton organization
Source: MGI
Traceable author statementⁱ
- 10090149

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Cysteine and glycine-rich protein 1 Alternative name(s): Cysteine-rich protein 1 Short name: CRP Short name: CRP1
Gene namesⁱ	Name:Csrp1 Synonyms:Crp1, Csrp
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 1

Organism-specific databases

MGIⁱ	MGI:88549. Csrp1.

Keywords - Cellular componentⁱ

Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000075716	1 – 193	Cysteine and glycine-rich protein 1Add BLAST		193

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	81	PhosphoserineBy similarity	1
Modified residueⁱ	84	N6-acetyllysineCombined sources	1
Cross-linkⁱ	91	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	112	N6-acetyllysineCombined sources	1
Modified residueⁱ	131	N6-acetyllysineCombined sources	1
Modified residueⁱ	137	N6-acetyllysineCombined sources	1
Modified residueⁱ	161	N6-acetyllysineCombined sources	1
Modified residueⁱ	192	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDⁱ	P97315.
PaxDbⁱ	P97315.
PeptideAtlas More...PeptideAtlasⁱ	P97315.
PRIDEⁱ	P97315.

PTM databases

iPTMnetⁱ	P97315.
PhosphoSitePlusⁱ	P97315.
SwissPalmⁱ	P97315.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000026421.
CleanExⁱ	MM_CSRP1.
ExpressionAtlasⁱ	P97315. baseline and differential.
Genevisibleⁱ	P97315. MM.

Interactionⁱ

Subunit structureⁱ

Interacts with ASCC1; ASCC2 AND TRIP4.By similarity

Protein-protein interaction databases

BioGridⁱ	198952. 3 interactors.
IntActⁱ	P97315. 4 interactors.
Molecular INTeraction database More...MINTⁱ	P97315.
STRINGⁱ	10090.ENSMUSP00000027677.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P97315.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	10 – 61	LIM zinc-binding 1PROSITE-ProRule annotationAdd BLAST		52
Domainⁱ	119 – 170	LIM zinc-binding 2PROSITE-ProRule annotationAdd BLAST		52

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	64 – 69	Nuclear localization signalSequence analysis		6

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	63 – 78	Gly-richAdd BLAST		16
Compositional biasⁱ	176 – 187	Gly-richAdd BLAST		12

Keywords - Domainⁱ

LIM domain, Repeat

Phylogenomic databases

eggNOGⁱ	ENOG410ITI1. Eukaryota. ENOG4111F3Y. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074548.
HOGENOMⁱ	HOG000111233.
HOVERGENⁱ	HBG051143.
InParanoidⁱ	P97315.
KEGG Orthology (KO) More...KOⁱ	K09377.
OMAⁱ	RCPRCTQ.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G11RX.
PhylomeDBⁱ	P97315.
TreeFamⁱ	TF313758.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001781. Znf_LIM.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00412. LIM. 2 hits.
SMARTⁱ	View protein in SMART SM00132. LIM. 2 hits.
PROSITEⁱ	View protein in PROSITE PS00478. LIM_DOMAIN_1. 2 hits. PS50023. LIM_DOMAIN_2. 2 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

P97315-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPNWGGGKKC GVCQKTVYFA EEVQCEGNSF HKSCFLCMVC KKNLDSTTVA 
        60         70         80         90        100
VHGEEIYCKS CYGKKYGPKG YGYGQGAGTL STDKGESLGI KHEEAPGHRP 
       110        120        130        140        150
TTNPNASKFA QKIGGSERCP RCSQAVYAAE KVIGAGKSWH KSCFRCAKCG 
       160        170        180        190 
KGLESTTLAD KDGEIYCKGC YAKNFGPKGF GFGQGAGALV HSE

Length:193

Mass (Da):20,583

Last modified:January 23, 2007 - v3

Checksum:ⁱAC69703ABD68C97A

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D88793 mRNA. Translation: BAA13723.1. AF092921 mRNA. Translation: AAD19352.1. AK077787 mRNA. Translation: BAC37009.1. AK087436 mRNA. Translation: BAC39873.1. BC006912 mRNA. Translation: AAH06912.1.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS15320.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_031817.1. NM_007791.5.
UniGeneⁱ	Mm.196484.

Genome annotation databases

Ensemblⁱ	ENSMUST00000027677; ENSMUSP00000027677; ENSMUSG00000026421. ENSMUST00000097561; ENSMUSP00000095169; ENSMUSG00000026421.
GeneIDⁱ	13007.
KEGGⁱ	mmu:13007.
UCSC genome browser More...UCSCⁱ	uc007cto.1. mouse.

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P97315	F7HCD8 F6XNE4 G7NWF3 A0A0D9RNF7 A0A2K6KWH0 A0A2K6CW11 A0A2K5MFH6 A0A2K6QIZ5 A0A096MSL0 A0A2K5DDS3 +12	Macaca mulatta (Rhesus macaque) Callithrix jacchus (White-tufted-ear marmoset) Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti) Macaca nemestrina (Pig-tailed macaque) Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys) Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana) Papio anubis (Olive baboon) Aotus nancymaae (Ma's night monkey) And more	193	UniRef100_P97315	Cluster: Cysteine and glycine-rich protein 1	23

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P97315	P67966 P67967 A0A226NIM0 G1MT36 UPI0003F182EF UPI0009480520 UPI00064B8668 A0A1S3FAK7 A0A1S3F8B8 UPI0002C557B8 +159	Gallus gallus (Chicken) Coturnix japonica (Japanese quail) (Coturnix coturnix japonica) Callipepla squamata (Scaled quail) Meleagris gallopavo (Wild turkey) Chrysochloris asiatica (Cape golden mole) Ailuropoda melanoleuca (Giant panda) Ochotona princeps (Southern American pika) Dipodomys ordii (Ord's kangaroo rat) Odobenus rosmarus divergens (Pacific walrus) Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis) And more	192	UniRef90_P67966	Cluster: Cysteine and glycine-rich protein 1	170

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
P97315	P67966 P67967 A0A226NIM0 G1MT36 UPI0003F182EF UPI0009480520 UPI00064B8668 A0A1S3FAK7 A0A1S3F8B8 UPI00053F3561 +628	Gallus gallus (Chicken) Coturnix japonica (Japanese quail) (Coturnix coturnix japonica) Callipepla squamata (Scaled quail) Meleagris gallopavo (Wild turkey) Chrysochloris asiatica (Cape golden mole) Ailuropoda melanoleuca (Giant panda) Ochotona princeps (Southern American pika) Dipodomys ordii (Ord's kangaroo rat) Fukomys damarensis (Damaraland mole rat) (Cryptomys damarensis) Odobenus rosmarus divergens (Pacific walrus) And more	192	UniRef50_P67966	Cluster: Cysteine and glycine-rich protein 1	639

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D88793 mRNA. Translation: BAA13723.1. AF092921 mRNA. Translation: AAD19352.1. AK077787 mRNA. Translation: BAC37009.1. AK087436 mRNA. Translation: BAC39873.1. BC006912 mRNA. Translation: AAH06912.1.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS15320.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_031817.1. NM_007791.5.
UniGeneⁱ	Mm.196484.

3D structure databases

ProteinModelPortalⁱ	P97315.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	198952. 3 interactors.
IntActⁱ	P97315. 4 interactors.
Molecular INTeraction database More...MINTⁱ	P97315.
STRINGⁱ	10090.ENSMUSP00000027677.

PTM databases

iPTMnetⁱ	P97315.
PhosphoSitePlusⁱ	P97315.
SwissPalmⁱ	P97315.

Proteomic databases

EPDⁱ	P97315.
PaxDbⁱ	P97315.
PeptideAtlas More...PeptideAtlasⁱ	P97315.
PRIDEⁱ	P97315.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000027677; ENSMUSP00000027677; ENSMUSG00000026421. ENSMUST00000097561; ENSMUSP00000095169; ENSMUSG00000026421.
GeneIDⁱ	13007.
KEGGⁱ	mmu:13007.
UCSC genome browser More...UCSCⁱ	uc007cto.1. mouse.

Organism-specific databases

CTDⁱ	1465.
MGIⁱ	MGI:88549. Csrp1.

Phylogenomic databases

eggNOGⁱ	ENOG410ITI1. Eukaryota. ENOG4111F3Y. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074548.
HOGENOMⁱ	HOG000111233.
HOVERGENⁱ	HBG051143.
InParanoidⁱ	P97315.
KEGG Orthology (KO) More...KOⁱ	K09377.
OMAⁱ	RCPRCTQ.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G11RX.
PhylomeDBⁱ	P97315.
TreeFamⁱ	TF313758.

Miscellaneous databases

ChiTaRSⁱ	Csrp1. mouse.
Protein Ontology More...PROⁱ	PR:P97315.
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000026421.
CleanExⁱ	MM_CSRP1.
ExpressionAtlasⁱ	P97315. baseline and differential.
Genevisibleⁱ	P97315. MM.

Family and domain databases

InterProⁱ	View protein in InterPro IPR001781. Znf_LIM.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00412. LIM. 2 hits.
SMARTⁱ	View protein in SMART SM00132. LIM. 2 hits.
PROSITEⁱ	View protein in PROSITE PS00478. LIM_DOMAIN_1. 2 hits. PS50023. LIM_DOMAIN_2. 2 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CSRP1_MOUSE
Accessionⁱ	P97315Primary (citable) accession number: P97315
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	May 24, 2004
	Last sequence update:	January 23, 2007
	Last modified:	February 28, 2018
	This is version 141 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Direct protein sequencing, Reference proteome

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P97315 (CSRP1_MOUSE)

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Cysteine and glycine-rich protein 1

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Cytoskeleton

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Motif

Compositional bias

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ