UniProtKB - P97315 (CSRP1_MOUSE)
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Protein
Cysteine and glycine-rich protein 1
Gene
Csrp1
Organism
Mus musculus (Mouse)
Status
Functioni
Could play a role in neuronal development.By similarity
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- actin cytoskeleton organization Source: MGI
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Cysteine and glycine-rich protein 1Alternative name(s): Cysteine-rich protein 1 Short name: CRP Short name: CRP1 |
Gene namesi | Name:Csrp1 Synonyms:Crp1, Csrp |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:88549. Csrp1. |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000075716 | 1 – 193 | Cysteine and glycine-rich protein 1Add BLAST | 193 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 81 | PhosphoserineBy similarity | 1 | |
Modified residuei | 84 | N6-acetyllysineCombined sources | 1 | |
Cross-linki | 91 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 112 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 131 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 137 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 161 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 192 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | P97315. |
PaxDbi | P97315. |
PeptideAtlasi | P97315. |
PRIDEi | P97315. |
PTM databases
iPTMneti | P97315. |
PhosphoSitePlusi | P97315. |
SwissPalmi | P97315. |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000026421. |
CleanExi | MM_CSRP1. |
ExpressionAtlasi | P97315. baseline and differential. |
Genevisiblei | P97315. MM. |
Interactioni
Subunit structurei
Interacts with ASCC1; ASCC2 AND TRIP4.By similarity
Protein-protein interaction databases
BioGridi | 198952. 3 interactors. |
IntActi | P97315. 4 interactors. |
MINTi | P97315. |
STRINGi | 10090.ENSMUSP00000027677. |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 10 – 61 | LIM zinc-binding 1PROSITE-ProRule annotationAdd BLAST | 52 | |
Domaini | 119 – 170 | LIM zinc-binding 2PROSITE-ProRule annotationAdd BLAST | 52 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 64 – 69 | Nuclear localization signalSequence analysis | 6 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 63 – 78 | Gly-richAdd BLAST | 16 | |
Compositional biasi | 176 – 187 | Gly-richAdd BLAST | 12 |
Keywords - Domaini
LIM domain, RepeatPhylogenomic databases
eggNOGi | ENOG410ITI1. Eukaryota. ENOG4111F3Y. LUCA. |
GeneTreei | ENSGT00550000074548. |
HOGENOMi | HOG000111233. |
HOVERGENi | HBG051143. |
InParanoidi | P97315. |
KOi | K09377. |
OMAi | RCPRCTQ. |
OrthoDBi | EOG091G11RX. |
PhylomeDBi | P97315. |
TreeFami | TF313758. |
Family and domain databases
InterProi | View protein in InterPro IPR001781. Znf_LIM. |
Pfami | View protein in Pfam PF00412. LIM. 2 hits. |
SMARTi | View protein in SMART SM00132. LIM. 2 hits. |
PROSITEi | View protein in PROSITE PS00478. LIM_DOMAIN_1. 2 hits. PS50023. LIM_DOMAIN_2. 2 hits. |
i Sequence
Sequence statusi: Complete.
P97315-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPNWGGGKKC GVCQKTVYFA EEVQCEGNSF HKSCFLCMVC KKNLDSTTVA
60 70 80 90 100
VHGEEIYCKS CYGKKYGPKG YGYGQGAGTL STDKGESLGI KHEEAPGHRP
110 120 130 140 150
TTNPNASKFA QKIGGSERCP RCSQAVYAAE KVIGAGKSWH KSCFRCAKCG
160 170 180 190
KGLESTTLAD KDGEIYCKGC YAKNFGPKGF GFGQGAGALV HSE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D88793 mRNA. Translation: BAA13723.1. AF092921 mRNA. Translation: AAD19352.1. AK077787 mRNA. Translation: BAC37009.1. AK087436 mRNA. Translation: BAC39873.1. BC006912 mRNA. Translation: AAH06912.1. |
CCDSi | CCDS15320.1. |
RefSeqi | NP_031817.1. NM_007791.5. |
UniGenei | Mm.196484. |
Genome annotation databases
Ensembli | ENSMUST00000027677; ENSMUSP00000027677; ENSMUSG00000026421. ENSMUST00000097561; ENSMUSP00000095169; ENSMUSG00000026421. |
GeneIDi | 13007. |
KEGGi | mmu:13007. |
UCSCi | uc007cto.1. mouse. |
Similar proteinsi
Entry informationi
Entry namei | CSRP1_MOUSE | |
Accessioni | P97315Primary (citable) accession number: P97315 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 24, 2004 |
Last sequence update: | January 23, 2007 | |
Last modified: | February 28, 2018 | |
This is version 141 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |