##gff-version 3
P97292	UniProtKB	Chain	1	397	.	.	.	ID=PRO_0000069685;Note=Histamine H2 receptor	
P97292	UniProtKB	Topological domain	1	22	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Transmembrane	23	44	.	.	.	Note=Helical%3B Name%3D1;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Topological domain	45	57	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Transmembrane	58	81	.	.	.	Note=Helical%3B Name%3D2;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Topological domain	82	92	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Transmembrane	93	114	.	.	.	Note=Helical%3B Name%3D3;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Topological domain	115	134	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Transmembrane	135	159	.	.	.	Note=Helical%3B Name%3D4;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Topological domain	160	179	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Transmembrane	180	203	.	.	.	Note=Helical%3B Name%3D5;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Topological domain	204	233	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Transmembrane	234	257	.	.	.	Note=Helical%3B Name%3D6;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Topological domain	258	266	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Transmembrane	267	288	.	.	.	Note=Helical%3B Name%3D7;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Topological domain	289	397	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Site	98	98	.	.	.	Note=Essential for histamine binding;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P97292	UniProtKB	Site	185	185	.	.	.	Note=Essential for tiotidine binding and implicated in histamine binding;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P97292	UniProtKB	Site	189	189	.	.	.	Note=Implicated in histamine binding;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P97292	UniProtKB	Lipidation	304	304	.	.	.	Note=S-palmitoyl cysteine;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P97292	UniProtKB	Glycosylation	4	4	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P97292	UniProtKB	Disulfide bond	91	173	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00521	
P97292	UniProtKB	Sequence conflict	85	85	.	.	.	Note=S->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P97292	UniProtKB	Sequence conflict	263	263	.	.	.	Note=A->P;Ontology_term=ECO:0000305;evidence=ECO:0000305