P96994 (GALT_STRMU) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 84.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Galactose-1-phosphate uridylyltransferase Short name=Gal-1-P uridylyltransferase EC=2.7.7.12 Alternative name(s): UDP-glucose--hexose-1-phosphate uridylyltransferase | ||||
| Gene names |
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| Organism | Streptococcus mutans [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 1309 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus |
Protein attributes
| Sequence length | 491 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | UDP-glucose + alpha-D-galactose 1-phosphate = alpha-D-glucose 1-phosphate + UDP-galactose. HAMAP MF_00571 |
| Pathway | Carbohydrate metabolism; galactose metabolism. HAMAP MF_00571 |
| Subcellular location | Cytoplasm Potential HAMAP MF_00571. |
| Sequence similarities | Belongs to the galactose-1-phosphate uridylyltransferase type 2 family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Carbohydrate metabolism Galactose metabolism |
| Cellular component | Cytoplasm |
| Molecular function | Nucleotidyltransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | galactose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | UDP-glucose:hexose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 491 | 491 | Galactose-1-phosphate uridylyltransferase HAMAP MF_00571 | PRO_0000169913 | |||||
Experimental info | |||||||||
| Sequence conflict | 27 | 1 | S → R in AAB49737. Ref.1 | ||||||
| Sequence conflict | 48 | 1 | L → R in AAB49737. Ref.1 | ||||||
| Sequence conflict | 98 | 1 | N → Y in AAB49737. Ref.1 | ||||||
| Sequence conflict | 117 | 1 | N → D in AAB49737. Ref.1 | ||||||
| Sequence conflict | 286 | 1 | R → H in AAB49737. Ref.1 | ||||||
| Sequence conflict | 383 | 1 | I → V in AAB49737. Ref.1 | ||||||
| Sequence conflict | 452 | 1 | I → V in AAB49737. Ref.1 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Organization and nucleotide sequence of the Streptococcus mutans galactose operon." Ajdic D., Sutcliffe I.C., Russell R.R.B., Ferretti J.J. Gene 180:137-144(1996) [PubMed: 8973358] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Ingbritt. |
| [2] | "Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen." Ajdic D.J., McShan W.M., McLaughlin R.E., Savic G., Chang J., Carson M.B., Primeaux C., Tian R., Kenton S., Jia H.G., Lin S.P., Qian Y., Li S., Zhu H., Najar F.Z., Lai H., White J., Roe B.A., Ferretti J.J. Proc. Natl. Acad. Sci. U.S.A. 99:14434-14439(2002) [PubMed: 12397186] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700610 / UA159 / Serotype c. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | U21942 Genomic DNA. Translation: AAB49737.1. AE014133 Genomic DNA. Translation: AAN58601.1. |
| PIR | JC5312. |
| RefSeq | NP_721295.1. NC_004350.2. |
3D structure databases | |
| ProteinModelPortal | P96994. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBSTRT00000014081; EBSTRP00000013563; EBSTRG00000014081. |
| GeneID | 1028252. |
| GenomeReviews | Gene locus SMU_887 in contig AE014133_GR. |
| KEGG | smu:SMU_887. |
| NMPDR | fig|210007.1.peg.808. |
| PATRIC | 19663923. VBIStrMut61772_0794. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| GeneTree | EBGT00050000027103. |
| HOGENOM | HBG337915. |
| OMA | HYFIGSN. |
| ProtClustDB | PRK05270. |
Enzyme and pathway databases | |
| BioCyc | SMUT210007:SMU_887-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00571. GalP_UDP_trans. [Tree] |
| InterPro | IPR000766. GalP_uridyl_Trfase_II. IPR023425. GalP_uridyl_Trfase_II_CS. IPR005850. GalP_Utransf_C. IPR005849. GalP_Utransf_N. [Graphical view] |
| KO | K00965. |
| Pfam | PF02744. GalP_UDP_tr_C. 1 hit. PF01087. GalP_UDP_transf. 1 hit. [Graphical view] |
| PIRSF | PIRSF006005. GalT_BS. 1 hit. |
| TIGRFAMs | TIGR01239. GalT_2. 1 hit. |
| PROSITE | PS01163. GAL_P_UDP_TRANSF_II. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | GALT_STRMU | ||||||||
| Accession | Primary (citable) accession number: P96994 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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