P96928 (Y637_MYCTU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UPF0336 protein Rv0637/MT0666

Gene names

Ordered Locus Names:	Rv0637, MT0666
ORF Names:	MTCY20H10.18

Organism

Mycobacterium tuberculosis [Reference proteome] [HAMAP]

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	166 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the UPF0336 family.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	fatty acid elongation Inferred from direct assay PubMed 17804795. Source: MTBBASE long-chain fatty acid biosynthetic process Inferred from direct assay PubMed 17804795. Source: MTBBASE
Cellular_component	plasma membrane Inferred from direct assay PubMed 14532352. Source: MTBBASE
Molecular_function	3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity Inferred from direct assay PubMed 17804795. Source: MTBBASE
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 166	166	UPF0336 protein Rv0637/MT0666 HAMAP-Rule MF_00799		PRO_0000216144

Sequences

	Sequence		Length	Mass (Da)
	P96928 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: 71BE5CF102B02BDA	FASTA	166	18,930
	10 20 30 40 50 60 MALKTDIRGM IWRYPDYFIV GREQCREFAR AVKCDHPAFF SEEAAADLGY DALVAPLTFV 70 80 90 100 110 120 TILAKYVQLD FFRHVDVGME TMQIVQVDQR FVFHKPVLAG DKLWARMDIH SVDERFGADI 130 140 150 160 VVTRNLCTND DGELVMEAYT TLMGQQGDGS ARLKWDKESG QVIRTA

References

[1]

"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.

[2]

"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L., Delcher A., Utterback T.R. , Weidman J.F., Khouri H.M., Gill J., Mikula A., Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX842574 Genomic DNA. Translation: CAB07096.1. AE000516 Genomic DNA. Translation: AAK44891.1. AL123456 Genomic DNA. Translation: CCP43380.1.
PIR	B70613.
RefSeq	NP_215151.1. NC_000962.3. NP_335077.1. NC_002755.2. YP_006513978.1. NC_018143.1.
3D structure databases
ProteinModelPortal	P96928.
SMR	P96928. Positions 82-145.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-46459N.
STRING	83332.Rv0637.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAK44891; AAK44891; MT0666.
GeneID	13318522. 888019. 925948.
KEGG	mtc:MT0666. mtu:Rv0637. mtv:RVBD_0637.
PATRIC	18123185. VBIMycTub22151_0723.
Organism-specific databases
TubercuList	Rv0637.
Phylogenomic databases
eggNOG	NOG08314.
HOGENOM	HOG000249016.
OMA	NSISAGW.
ProtClustDB	PRK13691.
Enzyme and pathway databases
BioCyc	MetaCyc:RV0637-MONOMER.
Family and domain databases
HAMAP	MF_00799. UPF0336.
InterPro	IPR016709. UPF0336. [Graphical view]
PIRSF	PIRSF018072. UCP018072. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Y637_MYCTU

Accession

Primary (citable) accession number: P96928
Secondary accession number(s): L0T4B1, Q7D9H8

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 25, 2004
Last sequence update:	May 1, 1997
Last modified:	May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program