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Protein
Submitted name:

Leucine-responsive regulatory protein

Gene

lrp

Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi24 – 43H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

  • amino acid binding Source: MTBBASE
  • DNA binding Source: MTBBASE
  • sequence-specific DNA binding Source: InterPro
  • transcription factor activity, sequence-specific DNA binding Source: InterPro

GO - Biological processi

  • protein homooligomerization Source: MTBBASE
  • transcription, DNA-templated Source: UniProtKB-UniRule

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Leucine-responsive regulatory proteinImported
Gene namesi
Name:lrpImported
Ordered Locus Names:MT3390Imported
OrganismiMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)Imported
Taxonomic identifieri83331 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001020 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2IVMX-ray2.50A/B1-150[»]
2QZ8X-ray2.16A/B/C/D5-150[»]
2VBWX-ray2.20A/B1-150[»]
2VBXX-ray2.75A/B1-150[»]
2VBYX-ray2.80A/B1-150[»]
2VBZX-ray2.80A/B1-150[»]
2VC0X-ray2.50A/B1-150[»]
2VC1X-ray2.75A/B1-150[»]
2W24X-ray2.50A/B1-150[»]
2W25X-ray2.15A/B1-150[»]
2W29X-ray4.10A/B/C/D1-150[»]
ProteinModelPortaliP96896.
SMRiP96896.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 66HTH asnC-type DNA-bindingInterPro annotationAdd BLAST62

Phylogenomic databases

HOGENOMiHOG000115327.
KOiK03719.
OrthoDBiPOG091H02L8.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000485. AsnC-type_HTH_dom.
IPR011008. Dimeric_a/b-barrel.
IPR019888. Tscrpt_reg_AsnC-typ.
IPR019887. Tscrpt_reg_AsnC/Lrp_C.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF01037. AsnC_trans_reg. 1 hit.
PF13404. HTH_AsnC-type. 1 hit.
PRINTSiPR00033. HTHASNC.
SMARTiView protein in SMART
SM00344. HTH_ASNC. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF54909. SSF54909. 1 hit.
PROSITEiView protein in PROSITE
PS50956. HTH_ASNC_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P96896-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEALDDIDR ILVRELAADG RATLSELATR AGLSVSAVQS RVRRLESRGV
60 70 80 90 100
VQGYSARINP EAVGHLLSAF VAITPLDPSQ PDDAPARLEH IEEVESCYSV
110 120 130 140 150
AGEESYVLLV RVASARALED LLQRIRTTAN VRTRSTIILN TFYSDRQHIP
Length:150
Mass (Da):16,511
Last modified:May 1, 1997 - v1
Checksum:iEE59E5ED33D88CCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000516 Genomic DNA. Translation: AAK47733.1.
PIRiD70981.
RefSeqiWP_003417179.1. NZ_KK341227.1.

Genome annotation databases

EnsemblBacteriaiAAK47733; AAK47733; MT3390.
KEGGimtc:MT3390.
PATRICifig|83331.31.peg.3648.

Similar proteinsi

Entry informationi

Entry nameiP96896_MYCTO
AccessioniPrimary (citable) accession number: P96896
Secondary accession number(s): F2GKW4, Q7D5R8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: August 30, 2017
This is version 138 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported