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Protein
Submitted name:

BirA bifunctional protein

Gene

birA

Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • biotin metabolic process Source: MTBBASE
  • protein biotinylation Source: MTBBASE

Keywordsi

Molecular functionLigaseImported

Enzyme and pathway databases

BRENDAi6.3.4.15. 3445.

Names & Taxonomyi

Protein namesi
Submitted name:
BirA bifunctional proteinImported (EC:6.3.4.15Imported)
Gene namesi
Name:birAImported
Ordered Locus Names:MT3379Imported
OrganismiMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)Imported
Taxonomic identifieri83331 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001020 Componenti: Chromosome

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL3102688.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CGHX-ray1.80A/B1-266[»]
3L1AX-ray2.69A/B1-266[»]
3L2ZX-ray2.80A/B1-266[»]
3RUXX-ray1.70A/B2-266[»]
DisProtiDP01091.
ProteinModelPortaliP96884.
SMRiP96884.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 147BPL/LPL catalyticInterPro annotationAdd BLAST91
Domaini218 – 264BPL_CInterPro annotationAdd BLAST47

Phylogenomic databases

HOGENOMiHOG000041813.
KOiK03524.
OrthoDBiPOG091H01NJ.

Family and domain databases

CDDicd16442. BPL. 1 hit.
InterProiView protein in InterPro
IPR004408. Biotin_CoA_COase_ligase.
IPR003142. BPL_C.
IPR004143. BPL_LPL_catalytic.
PANTHERiPTHR12835:SF10. PTHR12835:SF10. 1 hit.
PfamiView protein in Pfam
PF02237. BPL_C. 1 hit.
PF03099. BPL_LplA_LipB. 1 hit.
TIGRFAMsiTIGR00121. birA_ligase. 1 hit.

Sequencei

Sequence statusi: Complete.

P96884-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDRDRLRPP LDERSLRDQL IGAGSGWRQL DVVAQTGSTN ADLLARAASG
60 70 80 90 100
ADIDGVVLIA EHQTAGRGRH GRGWAATARA QIILSVGVRV VDVPVQAWGW
110 120 130 140 150
LSLAAGLAVL DSVAPLIAVP PAETGLKWPN DVLARGGKLA GILAEVAQPF
160 170 180 190 200
VVLGVGLNVT QAPEEVDPDA TSLLDLGVAA PDRNRIASRL LRELEARIIQ
210 220 230 240 250
WRNANPQLAA DYRARSLTIG SRVRVELPGG QDVVGIARDI DDQGRLCLDV
260
GGRTVVVSAG DVVHLR
Length:266
Mass (Da):28,121
Last modified:July 1, 1997 - v2
Checksum:i3DE5CE48830F070F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000516 Genomic DNA. Translation: AAK47721.1.
PIRiH70979.
RefSeqiWP_003899999.1. NZ_KK341227.1.

Genome annotation databases

EnsemblBacteriaiAAK47721; AAK47721; MT3379.
KEGGimtc:MT3379.
PATRICifig|83331.31.peg.3636.

Similar proteinsi

Entry informationi

Entry nameiP96884_MYCTO
AccessioniPrimary (citable) accession number: P96884
Secondary accession number(s): F2GKV2, Q7D5S4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: July 1, 1997
Last modified: September 27, 2017
This is version 131 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported