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Protein
Submitted name:

Uncharacterized protein

Gene

MT0162

Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • phosphatase activity Source: MTBBASE
  • phosphatidylinositol trisphosphate phosphatase activity Source: MTBBASE
  • protein serine/threonine phosphatase activity Source: MTBBASE
  • protein tyrosine phosphatase activity Source: MTBBASE

GO - Biological processi

  • growth of symbiont in host cell Source: MTBBASE
  • pathogenesis Source: MTBBASE
  • protein dephosphorylation Source: MTBBASE
Complete GO annotation...

Enzyme and pathway databases

BioCyciMTBCDC1551:GT3Z-4461-MONOMER.
BRENDAi3.1.3.48. 3445.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Ordered Locus Names:MT0162Imported
OrganismiMycobacterium tuberculosis (strain CDC 1551 / Oshkosh)Imported
Taxonomic identifieri83331 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001020 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • extracellular region Source: MTBBASE
Complete GO annotation...

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL4540.

Interactioni

Chemistry databases

BindingDBiP96830.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1YWFX-ray1.71A1-276[»]
2OZ5X-ray2.00A/B1-276[»]
ProteinModelPortaliP96830.
SMRiP96830.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini140 – 214TYR_PHOSPHATASE_2InterPro annotationAdd BLAST75

Phylogenomic databases

HOGENOMiHOG000036053.
KOiK01104.
OrthoDBiPOG091H07QV.

Family and domain databases

Gene3Di3.90.190.10. 2 hits.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR026893. Tyr/Ser_Pase_IphP-type.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PfamiPF13350. Y_phosphatase3. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P96830-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVRELPGAW NFRDVADTAT ALRPGRLFRS SELSRLDDAG RATLRRLGIT
60 70 80 90 100
DVADLRSSRE VARRGPGRVP DGIDVHLLPF PDLADDDADD SAPHETAFKR
110 120 130 140 150
LLTNDGSNGE SGESSQSIND AATRYMTDEY RQFPTRNGAQ RALHRVVTLL
160 170 180 190 200
AAGRPVLTHC FAGKDRTGFV VALVLEAVGL DRDVIVADYL RSNDSVPQLR
210 220 230 240 250
ARISEMIQQR FDTELAPEVV TFTKARLSDG VLGVRAEYLA AARQTIDETY
260 270
GSLGGYLRDA GISQATVNRM RGVLLG
Length:276
Mass (Da):30,154
Last modified:August 1, 1998 - v2
Checksum:i2794F56866D2E432
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000516 Genomic DNA. Translation: AAK44386.1.
PIRiD70618.
RefSeqiWP_003401010.1. NZ_KK341227.1.

Genome annotation databases

EnsemblBacteriaiAAK44386; AAK44386; MT0162.
KEGGimtc:MT0162.
PATRICi18122083. VBIMycTub22151_0176.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000516 Genomic DNA. Translation: AAK44386.1.
PIRiD70618.
RefSeqiWP_003401010.1. NZ_KK341227.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1YWFX-ray1.71A1-276[»]
2OZ5X-ray2.00A/B1-276[»]
ProteinModelPortaliP96830.
SMRiP96830.
ModBaseiSearch...
MobiDBiSearch...

Chemistry databases

BindingDBiP96830.
ChEMBLiCHEMBL4540.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK44386; AAK44386; MT0162.
KEGGimtc:MT0162.
PATRICi18122083. VBIMycTub22151_0176.

Phylogenomic databases

HOGENOMiHOG000036053.
KOiK01104.
OrthoDBiPOG091H07QV.

Enzyme and pathway databases

BioCyciMTBCDC1551:GT3Z-4461-MONOMER.
BRENDAi3.1.3.48. 3445.

Family and domain databases

Gene3Di3.90.190.10. 2 hits.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR026893. Tyr/Ser_Pase_IphP-type.
IPR000387. TYR_PHOSPHATASE_dom.
[Graphical view]
PfamiPF13350. Y_phosphatase3. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS50056. TYR_PHOSPHATASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiP96830_MYCTO
AccessioniPrimary (citable) accession number: P96830
Secondary accession number(s): F2GLV1, Q7DAD4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: August 1, 1998
Last modified: November 2, 2016
This is version 122 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.