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Protein
Submitted name:

Probable acyl-CoA dehydrogenase FadE1

Gene

fadE1

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

FADUniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Names & Taxonomyi

Protein namesi
Submitted name:
Probable acyl-CoA dehydrogenase FadE1Imported
Gene namesi
Name:fadE1Imported
Ordered Locus Names:Rv0131cImported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome

Organism-specific databases

TubercuListiRv0131c.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: MTBBASE

PTM / Processingi

Proteomic databases

PaxDbiP96808.
PRIDEiP96808.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv0131c.

Structurei

3D structure databases

ProteinModelPortaliP96808.
SMRiP96808.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 141Acyl-CoA_dh_NInterPro annotationAdd BLAST115
Domaini145 – 245Acyl-CoA_dh_MInterPro annotationAdd BLAST101
Domaini262 – 409Acyl-CoA_dh_1InterPro annotationAdd BLAST148

Sequence similaritiesi

Belongs to the acyl-CoA dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1960. LUCA.
HOGENOMiHOG000131660.
KOiK00249.
OMAiMMCERAV.
PhylomeDBiP96808.

Family and domain databases

Gene3Di1.10.540.10. 1 hit.
InterProiView protein in InterPro
IPR006091. Acyl-CoA_Oxase/DH_cen-dom.
IPR009075. AcylCo_DH/oxidase_C.
IPR013786. AcylCoA_DH/ox_N.
IPR009100. AcylCoA_DH/oxidase_NM_dom.
PfamiView protein in Pfam
PF00441. Acyl-CoA_dh_1. 1 hit.
PF02770. Acyl-CoA_dh_M. 1 hit.
PF02771. Acyl-CoA_dh_N. 1 hit.
SUPFAMiSSF47203. SSF47203. 1 hit.
SSF56645. SSF56645. 1 hit.

Sequencei

Sequence statusi: Complete.

P96808-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVRRRAGER LPTVWDFETD PQYQSKLDWV EKFMAEELEP LDLVALDPYD
60 70 80 90 100
KKNADTMAIL RPLQRQVKDQ GLWAAHLRPE LGGQGFGQVK LALLNEIIGR
110 120 130 140 150
SRWAPSAFGC QAPDSGNAEI LALFGTDEQK ARYLRPLLDG EITSCYSMTE
160 170 180 190 200
PQGGSDPGLF VTAATRDAAG NGDWIINGEK WFSTNAKHAS FFIVMAVTKP
210 220 230 240 250
EARTYEKMSL FIVPADTPGI EIVRNVGVGA ESTRHASHGY IRYHDVRVPA
260 270 280 290 300
DHVLGGEGQA FMIAQTRLGG GRIHHAMRTI ALARRAFDMM CERALSRQTR
310 320 330 340 350
HGRLADLQMT QEKIADSWIQ IEQFRLLVLR TAWLIDKHHD YQKVRRDIAA
360 370 380 390 400
VKVAMPQVLH DVVQRAMHLH GALGVSDEMP FVKMMLAAES LGIADGATEL
410 420 430 440
HKMTVARRTL REYQPVTTLF PSQHIPTRRA HAEAWLAQRL EHAIAEF
Length:447
Mass (Da):50,224
Last modified:May 1, 1997 - v1
Checksum:iE8145FFE8489D275
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA. Translation: CCP42856.1.
RefSeqiNP_214645.1. NC_000962.3.
WP_003400917.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiCCP42856; CCP42856; Rv0131c.
GeneIDi886874.
KEGGimtu:Rv0131c.
mtv:RVBD_0131c.
PATRICifig|83332.111.peg.152.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiP96808_MYCTU
AccessioniPrimary (citable) accession number: P96808
Secondary accession number(s): F2GLS8, I6X8L2, Q7DAF3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: June 7, 2017
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported