Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Secreted flagellin C

Gene

flaC

Organism
Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Plays a role in virulence.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processVirulence

Enzyme and pathway databases

BioCyciCJEJ192222:G1G1F-694-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Secreted flagellin C
Gene namesi
Name:flaC
Ordered Locus Names:Cj0720c
OrganismiCampylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)
Taxonomic identifieri192222 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000000799 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Disruption phenotypei

No visible effect on flagellar structure, cell shape or motility. Adheres to host epithelial cells (human HEp2) but invades less well (14% suriving bacteria, determined by bacterial counts from lysed cells after 2 hours of gentamicin treatment).1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001825991 – 249Secreted flagellin CAdd BLAST249

Post-translational modificationi

The secreted form is about 1 kDa larger than the whole cell lysate form, presumably due to post-translational modification. A 22 kDa form is also found in the secreted fraction, probably resulting from proteolysis.1 Publication

Proteomic databases

PaxDbiP96747

Interactioni

Protein-protein interaction databases

IntActiP96747 149 interactors.
STRINGi192222.Cj0720c

Structurei

3D structure databases

ProteinModelPortaliP96747
SMRiP96747
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG41090FP Bacteria
COG1344 LUCA
HOGENOMiHOG000101721
KOiK02406
OMAiEQTNFAG

Family and domain databases

InterProiView protein in InterPro
IPR001029 Flagellin_D0/D1
PfamiView protein in Pfam
PF00669 Flagellin_N, 1 hit

Sequencei

Sequence statusi: Complete.

P96747-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMISDATMMQ QNYYLNNAQK ASDKALENIA AVRAISGVDS ANLAIADSLR
60 70 80 90 100
SQSSTIDQGV ANAYDAIGVL QIADASLTNI SQSADRLNEL SVKMNNAALN
110 120 130 140 150
DSQKGMLRTE ATRIQESIND SFNNATYNGK NVFQTMNFVV GSGTETTNLN
160 170 180 190 200
PLATDGLSID SQDSITNFMD QLGSLRSEIG SGINAITSNI NASVQNSINS
210 220 230 240
KAAENNLLNN DMAKNVNDFN ANYLKENAAA FVAAQSNMQL QSKIANLLQ
Length:249
Mass (Da):26,606
Last modified:December 1, 2000 - v2
Checksum:iD233CE46547D4112
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti161S → N in AAB48473 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U85622 Genomic DNA Translation: AAB48473.1
AL111168 Genomic DNA Translation: CAL34857.1
PIRiC81343
RefSeqiWP_002858476.1, NC_002163.1
YP_002344138.1, NC_002163.1

Genome annotation databases

EnsemblBacteriaiCAL34857; CAL34857; Cj0720c
GeneIDi905038
KEGGicje:Cj0720c
PATRICifig|192222.6.peg.712

Similar proteinsi

Entry informationi

Entry nameiFLAC_CAMJE
AccessioniPrimary (citable) accession number: P96747
Secondary accession number(s): Q0PAF9, Q9PPI7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: February 28, 2018
This is version 100 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome