Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized carboxylesterase nap

Gene

nap

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

A carboxylic ester + H2O = an alcohol + a carboxylate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei130 – 1301Transition state stabilizerBy similarity
Active sitei274 – 2741Proton acceptorBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciBSUB:BSU05440-MONOMER.

Protein family/group databases

ESTHERibacsu-cbxnp. 6_AlphaBeta_hydrolase.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized carboxylesterase nap (EC:3.1.1.1)
Gene namesi
Name:nap
Ordered Locus Names:BSU05440
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 300300Uncharacterized carboxylesterase napPRO_0000360816Add
BLAST

Proteomic databases

PaxDbiP96688.

Interactioni

Subunit structurei

Monomer.1 Publication

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100003063.

Structurei

Secondary structure

1
300
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi13 – 2614Combined sources
Beta strandi34 – 385Combined sources
Beta strandi43 – 519Combined sources
Beta strandi57 – 615Combined sources
Turni64 – 663Combined sources
Helixi68 – 714Combined sources
Turni72 – 743Combined sources
Helixi75 – 817Combined sources
Beta strandi82 – 876Combined sources
Beta strandi92 – 954Combined sources
Helixi105 – 11814Combined sources
Beta strandi122 – 1298Combined sources
Helixi131 – 14212Combined sources
Helixi144 – 1463Combined sources
Beta strandi147 – 1548Combined sources
Beta strandi156 – 1583Combined sources
Helixi164 – 1718Combined sources
Turni172 – 1743Combined sources
Helixi178 – 1869Combined sources
Turni187 – 1893Combined sources
Helixi195 – 20612Combined sources
Beta strandi209 – 2113Combined sources
Beta strandi220 – 2223Combined sources
Helixi227 – 2315Combined sources
Beta strandi237 – 2426Combined sources
Helixi250 – 26011Combined sources
Beta strandi265 – 2695Combined sources
Helixi276 – 2794Combined sources
Helixi281 – 29212Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2R11X-ray1.96A/B/C/D1-294[»]
ProteinModelPortaliP96688.
SMRiP96688. Positions 7-294.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP96688.

Family & Domainsi

Sequence similaritiesi

Belongs to the AB hydrolase superfamily.Curated

Phylogenomic databases

eggNOGiENOG4108WC5. Bacteria.
COG0596. LUCA.
HOGENOMiHOG000091205.
InParanoidiP96688.
OMAiSSTMWYP.
PhylomeDBiP96688.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
[Graphical view]
PfamiPF12697. Abhydrolase_6. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

P96688-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNHSSSIPE LSDNGIRYYQ TYNESLSLWP VRCKSFYIST RFGQTHVIAS
60 70 80 90 100
GPEDAPPLVL LHGALFSSTM WYPNIADWSS KYRTYAVDII GDKNKSIPEN
110 120 130 140 150
VSGTRTDYAN WLLDVFDNLG IEKSHMIGLS LGGLHTMNFL LRMPERVKSA
160 170 180 190 200
AILSPAETFL PFHHDFYKYA LGLTASNGVE TFLNWMMNDQ NVLHPIFVKQ
210 220 230 240 250
FKAGVMWQDG SRNPNPNADG FPYVFTDEEL RSARVPILLL LGEHEVIYDP
260 270 280 290 300
HSALHRASSF VPDIEAEVIK NAGHVLSMEQ PTYVNERVMR FFNAETGISR
Length:300
Mass (Da):33,953
Last modified:May 1, 1997 - v1
Checksum:iFA818689172007AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001488 Genomic DNA. Translation: BAA19378.1.
AL009126 Genomic DNA. Translation: CAB12351.1.
PIRiC69664.
RefSeqiNP_388425.1. NC_000964.3.
WP_003242638.1. NZ_JNCM01000031.1.

Genome annotation databases

EnsemblBacteriaiCAB12351; CAB12351; BSU05440.
GeneIDi938069.
KEGGibsu:BSU05440.
PATRICi18972694. VBIBacSub10457_0568.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001488 Genomic DNA. Translation: BAA19378.1.
AL009126 Genomic DNA. Translation: CAB12351.1.
PIRiC69664.
RefSeqiNP_388425.1. NC_000964.3.
WP_003242638.1. NZ_JNCM01000031.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2R11X-ray1.96A/B/C/D1-294[»]
ProteinModelPortaliP96688.
SMRiP96688. Positions 7-294.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100003063.

Protein family/group databases

ESTHERibacsu-cbxnp. 6_AlphaBeta_hydrolase.

Proteomic databases

PaxDbiP96688.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12351; CAB12351; BSU05440.
GeneIDi938069.
KEGGibsu:BSU05440.
PATRICi18972694. VBIBacSub10457_0568.

Phylogenomic databases

eggNOGiENOG4108WC5. Bacteria.
COG0596. LUCA.
HOGENOMiHOG000091205.
InParanoidiP96688.
OMAiSSTMWYP.
PhylomeDBiP96688.

Enzyme and pathway databases

BioCyciBSUB:BSU05440-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP96688.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
[Graphical view]
PfamiPF12697. Abhydrolase_6. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNAP_BACSU
AccessioniPrimary (citable) accession number: P96688
Secondary accession number(s): Q797G3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: May 1, 1997
Last modified: September 7, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.