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Protein

C4-dicarboxylate transport protein

Gene

dctA

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Responsible for the transport of succinate and fumarate, but not malate, across the membrane.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processSymport, Transport

Enzyme and pathway databases

BioCyciBSUB:BSU04470-MONOMER

Protein family/group databases

TCDBi2.A.23.1.6 the dicarboxylate/amino acid:cation (na(+) or h(+)) symporter (daacs) family

Names & Taxonomyi

Protein namesi
Recommended name:
C4-dicarboxylate transport protein
Alternative name(s):
C4-dicarboxylate permease
Gene namesi
Name:dctA
Synonyms:dctP, ydbH
Ordered Locus Names:BSU04470
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei9 – 29HelicalSequence analysisAdd BLAST21
Transmembranei39 – 59HelicalSequence analysisAdd BLAST21
Transmembranei76 – 96HelicalSequence analysisAdd BLAST21
Transmembranei145 – 165HelicalSequence analysisAdd BLAST21
Transmembranei185 – 205HelicalSequence analysisAdd BLAST21
Transmembranei219 – 239HelicalSequence analysisAdd BLAST21
Transmembranei316 – 336HelicalSequence analysisAdd BLAST21
Transmembranei348 – 368HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002020901 – 421C4-dicarboxylate transport proteinAdd BLAST421

Proteomic databases

PaxDbiP96603
PRIDEiP96603

Expressioni

Inductioni

Induced by succinate and fumarate. Expression of dctA requires the DctB, DctS and DctR proteins and is decreased in the presence of malate.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100002528

Structurei

3D structure databases

ProteinModelPortaliP96603
SMRiP96603
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4107QJT Bacteria
COG1301 LUCA
HOGENOMiHOG000208775
InParanoidiP96603
KOiK11103
OMAiISHIGER
PhylomeDBiP96603

Family and domain databases

Gene3Di1.10.3860.10, 1 hit
HAMAPiMF_01300 C4_dicarb_transport, 1 hit
InterProiView protein in InterPro
IPR023954 C4_dicarb_transport
IPR001991 Na-dicarboxylate_symporter
IPR018107 Na-dicarboxylate_symporter_CS
IPR036458 Na:dicarbo_symporter_sf
PfamiView protein in Pfam
PF00375 SDF, 1 hit
SUPFAMiSSF118215 SSF118215, 1 hit
PROSITEiView protein in PROSITE
PS00713 NA_DICARBOXYL_SYMP_1, 1 hit
PS00714 NA_DICARBOXYL_SYMP_2, 1 hit

Sequencei

Sequence statusi: Complete.

P96603-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLFKNLTVQ VITAVIIGVI VGLVWPDVGK EMKPLGDTFI NAVKMVIAPI
60 70 80 90 100
IFFTIVLGIA KMGDMKKVGK VGGKAFIYFE VVTTLALIIG LFVVNIMKPG
110 120 130 140 150
AGLDYSKLEK GDVSQYTQNG GQGIDWIEFI THIVPSNMVD AFAKGDILQV
160 170 180 190 200
LFFSILFGVG LAALGEKGKS VIDFFDKVSH VFFKIIGYIM RAAPIGAFGA
210 220 230 240 250
MAYTIGHFGL DSIKPLASLM MSVYITMFLF VFVALNIICK LYGFSLWNYL
260 270 280 290 300
RFIKDELLIV LGTSSSESVL PRMMDKMERY GCSKSVVGLV IPTGYSFNLD
310 320 330 340 350
GTSIYLSMAT VFLAQVFGVD LSIGQQITII LVLMLTSKGA AGVTGSGFIV
360 370 380 390 400
LASTLSALQV IPLEGLALLL GVDRFMSEGR AIVNLIGNGI ATIIVAKSEN
410 420
EFDEAKSIEA VEGMKKMKTA V
Length:421
Mass (Da):45,441
Last modified:May 1, 1997 - v1
Checksum:i29FA5A6BD5DD7A5A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001488 Genomic DNA Translation: BAA19284.1
AL009126 Genomic DNA Translation: CAB12254.1
PIRiC69771
RefSeqiNP_388328.1, NC_000964.3
WP_003246626.1, NZ_JNCM01000031.1

Genome annotation databases

EnsemblBacteriaiCAB12254; CAB12254; BSU04470
GeneIDi938223
KEGGibsu:BSU04470
PATRICifig|224308.179.peg.473

Similar proteinsi

Entry informationi

Entry nameiDCTA_BACSU
AccessioniPrimary (citable) accession number: P96603
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: May 1, 1997
Last modified: May 23, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

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