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Protein

HTH-type transcriptional regulator LrpC

Gene

lrpC

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transcriptional regulator with a possible role in regulation of amino acid metabolism. Plays a role in the growth phase transition.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi22 – 41H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciBSUB:BSU04250-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional regulator LrpC
Gene namesi
Name:lrpC
Synonyms:ydaI
Ordered Locus Names:BSU04250
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001117401 – 144HTH-type transcriptional regulator LrpCAdd BLAST144

Proteomic databases

PaxDbiP96582
PRIDEiP96582

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100002413

Structurei

Secondary structure

1144
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi5 – 16Combined sources12
Helixi22 – 29Combined sources8
Helixi33 – 45Combined sources13
Beta strandi48 – 56Combined sources9
Helixi59 – 61Combined sources3
Beta strandi65 – 73Combined sources9
Helixi74 – 76Combined sources3
Helixi78 – 86Combined sources9
Beta strandi91 – 111Combined sources21
Helixi112 – 122Combined sources11
Turni123 – 125Combined sources3
Beta strandi126 – 136Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CFXX-ray2.40A/B/C/D/E/F/G/H1-144[»]
ProteinModelPortaliP96582
SMRiP96582
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP96582

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 64HTH asnC-typePROSITE-ProRule annotationAdd BLAST62

Phylogenomic databases

eggNOGiCOG1522 LUCA
HOGENOMiHOG000115327
InParanoidiP96582
KOiK03719
OMAiCRLYLHS
PhylomeDBiP96582

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000485 AsnC-type_HTH_dom
IPR011008 Dimeric_a/b-barrel
IPR019888 Tscrpt_reg_AsnC-typ
IPR019887 Tscrpt_reg_AsnC/Lrp_C
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF01037 AsnC_trans_reg, 1 hit
PRINTSiPR00033 HTHASNC
SMARTiView protein in SMART
SM00344 HTH_ASNC, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF54909 SSF54909, 1 hit
PROSITEiView protein in PROSITE
PS50956 HTH_ASNC_2, 1 hit

Sequencei

Sequence statusi: Complete.

P96582-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLDQIDLNI IEELKKDSRL SMRELGRKIK LSPPSVTERV RQLESFGIIK
60 70 80 90 100
QYTLEVDQKK LGLPVSCIVE ATVKNADYER FKSYIQTLPN IEFCYRIAGA
110 120 130 140
ACYMLKINAE SLEAVEDFIN KTSPYAQTVT HVIFSEIDTK NGRG
Length:144
Mass (Da):16,450
Last modified:May 30, 2000 - v2
Checksum:i78852BE30103417F
GO

Sequence cautioni

The sequence BAA19262 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB001488 Genomic DNA Translation: BAA19262.1 Different initiation.
AL009126 Genomic DNA Translation: CAB12232.1
PIRiF69653
RefSeqiNP_388306.1, NC_000964.3
WP_003246585.1, NZ_JNCM01000031.1

Genome annotation databases

EnsemblBacteriaiCAB12232; CAB12232; BSU04250
GeneIDi940147
KEGGibsu:BSU04250
PATRICifig|224308.179.peg.451

Similar proteinsi

Entry informationi

Entry nameiLRPC_BACSU
AccessioniPrimary (citable) accession number: P96582
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: May 23, 2018
This is version 131 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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