P96558 (P96558_AMYOR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glycosyltransferase GtfA EMBL AAB49292.1

Submitted name:
PCZA361.19 EMBL CAA11774.1

Gene names

Name:

gtfA EMBL AAB49292.1

Organism

Amycolatopsis orientalis (Nocardia orientalis) EMBL AAB49292.1

Taxonomic identifier

31958 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Amycolatopsis

Protein attributes

Sequence length	396 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Transferase EMBL AAB49292.1
Technical term	3D-structure PDB 3H4T PDB 1PNV PDB 1PN3 PDB 3H4I
Gene Ontology (GO)
Biological process	lipid glycosylation Inferred from electronic annotation. Source: InterPro
Molecular function	transferase activity, transferring hexosyl groups Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	P96558 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: A771471559C6CBF5	FASTA	396	41,662
	10 20 30 40 50 60 MRVLITGCGS RGDTEPLVAL AARLRELGAD ARMCLPPDYV ERCAEVGVPM VPVGRAVRAG 70 80 90 100 110 120 AREPGELPPG AAEVVTEVVA EWFDKVPAAI EGCDAVVTTG LLPAAVAVRS MAEKLGIPYR 130 140 150 160 170 180 YTVLSPDHLP SEQSQAERDM YNQGADRLFG DAVNSHRASI GLPPVEHLYD YGYTDQPWLA 190 200 210 220 230 240 ADPVLSPLRP TDLGTVQTGA WILPDERPLS AELEAFLAAG STPVYVGFGS SSRPATADAA 250 260 270 280 290 300 KMAIKAVRAS GRRIVLSRGW ADLVLPDDGA DCFVVGEVNL QELFGRVAAA IHHDSAGTTL 310 320 330 340 350 360 LAMRAGIPQI VVRRVVDNVV EQAYHADRVA ELGVGVAVDG PVPTIDSLSA ALDTALAPEI 370 380 390 RARATTVADT IRADGTTVAA QLLFDAVSLE KPTVPA

References

[1]	"Structure of the TDP-epi-vancosaminyltransferase GtfA from the chloroeremomycin biosynthetic pathway." Mulichak A.M., Losey H.C., Lu W., Wawrzak Z., Walsh C.T., Garavito R.M. Proc. Natl. Acad. Sci. U.S.A. 100:9238-9243(2003) [PubMed: 12874381] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS).
[2]	"Chimeric glycosyltransferases for the generation of hybrid glycopeptides." Truman A.W., Dias M.V., Wu S., Blundell T.L., Huang F., Spencer J.B. Chem. Biol. 16:676-685(2009) [PubMed: 19549605] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.15 ANGSTROMS) OF 3-383.
[3]	"Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic." van Wageningen A., Kirkpatrick P., Williams D., Harris B., Kershaw J., Lennard N., Jones M., Jones S., Solenberg P. Chem. Biol. 5:155-162(1998) [PubMed: 9545426] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[4]	"Production of hybrid glycopeptide antibiotics in vitro and in Streptomyces toyocaensis." Solenberg P.J., Matsushima P., Stack D.R., Wilkie S.C., Thompson R.C., Baltz R.H. Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: A82846 EMBL AAB49292.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

U84349 Genomic DNA. Translation: AAB49292.1.
AJ223998 Genomic DNA. Translation: CAA11774.1.

PIR

T30584.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1PN3	X-ray	2.80	A/B	1-396	[»]
1PNV	X-ray	2.80	A/B	1-396	[»]
3H4I	X-ray	1.30	A	3-383	[»]
3H4T	X-ray	1.15	A	3-383	[»]

ProteinModelPortal

P96558.

SMR

P96558. Positions 1-391.

ModBase

Search...

Protein family/group databases

CAZy

GT1. Glycosyltransferase Family 1.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

InterPro

IPR004276. Glyco_trans_28.
[Graphical view]

Pfam

PF03033. Glyco_transf_28. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

P96558_AMYOR

Accession

Primary (citable) accession number: P96558

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1997
Last sequence update:	May 1, 1997
Last modified:	July 27, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)