Reviewed,
UniProtKB/Swiss-Prot P96465 (BLA2_STEMA)
Last modified
September 22, 2009.
Version 49.
History...
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Beta-lactamase L2 EC=3.5.2.6 Alternative name(s): Penicillinase |
| Organism | Stenotrophomonas maltophilia (Pseudomonas maltophilia) (Xanthomonas maltophilia) |
| Taxonomic identifier | 40324 [NCBI] |
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Stenotrophomonas |
Protein attributes
| Sequence length | 303 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | A beta-lactam + H2O = a substituted beta-amino acid. |
| Post-translational modification | Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. |
| Sequence similarities | Belongs to the class-A beta-lactamase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Antibiotic resistance |
| Domain | Signal |
| Molecular function | Hydrolase |
| Gene Ontology (GO) | |
| Biological process | beta-lactam antibiotic catabolic process Inferred from electronic annotation. Source: InterPro response to antibioticInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | beta-lactamase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Sequence analysis and enzyme kinetics of the L2 serine beta-lactamase from Stenotrophomonas maltophilia." Walsh T.R., Macgowan A.P., Bennett P.M. Antimicrob. Agents Chemother. 41:1460-1464(1997) [PubMed: 9210666] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: IID 1275. |
Cross-references
Sequence databases | |
|---|---|
| Y08562 Genomic DNA. Translation: CAA69869.1. | |
3D structure databases | |
| HSSP | HSSP built from PDB template 1JTG based on UniProtKB P00810. |
| SMR | P96465. Positions 33-303. |
| ModBase | Search... |
Enzyme and pathway databases | |
| BRENDA | 3.5.2.6. 39210. |
Family and domain databases | |
| InterPro | IPR001466. Beta_lactamase-related. IPR000871. Beta_lactamase_A/D. IPR006311. TAT_signal. IPR017909. Twin_arg_translocation_Tat. [Graphical view] |
| Pfam | PF00144. Beta-lactamase. 1 hit. [Graphical view] |
| PRINTS | PR00118. BLACTAMASEA. |
| TIGRFAMs | TIGR01409. TAT_signal_seq. 1 hit. |
| PROSITE | PS00146. BETA_LACTAMASE_A. 1 hit. PS51318. TAT. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BLA2_STEMA | ||||||||
| Accession | Primary (citable) accession number: P96465 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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