P96404 (P96404_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Enoyl-CoA hydratase/isomerase family protein EMBL AAK44453.1

Submitted name:
PROBABLE ENOYL-CoA HYDRATASE ECHA1 (ENOYL HYDRASE) (UNSATURATED ACYL-CoA HYDRATASE) (CROTONASE) EMBL CAB06989.1
EC=4.2.1.17 EMBL CAB06989.1

Gene names

Name:	echA1 EMBL CAB06989.1
Ordered Locus Names:	MT0232, Rv0222

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	262 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the enoyl-CoA hydratase/isomerase family. RuleBase RU003707

Ontologies

Keywords
Molecular function	Isomerase EMBL AAK44453.1 Lyase EMBL CAB06989.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	enoyl-CoA hydratase activity Inferred from electronic annotation. Source: EC isomerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	P96404 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: D58E415D6DAA2772	FASTA	262	27,280
	10 20 30 40 50 60 MSSESDAANT EPEVLVEQRD RILIITINRP KAKNAVNAAV SRGLADAMDQ LDGDAGLSVA 70 80 90 100 110 120 ILTGGGGSFC AGMDLKAFAR GENVVVEGRG LGFTERPPTK PLIAAVEGYA LAGGTELALA 130 140 150 160 170 180 ADLIVAARDS AFGIPEVKRG LVAGGGGLLR LPERIPYAIA MELALTGDNL PAERAHELGL 190 200 210 220 230 240 VNVLAEPGTA LDAAIALAEK ITANGPLAVV ATKRIITESR GWSPDTMFAE QMKILVPVFT 250 260 SNDAKEGAIA FAERRRPRWT GT

References

[1]	"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.
[2]	"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J., DeBoy R., Dodson R., Gwinn M., Haft D., Hickey E., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M., Salzberg S.L., Delcher A., Utterback T. , Weidman J., Khouri H., Gill J., Mikula A., Bishai W., Jacobs Jr W.R. Jr, Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000516 Genomic DNA. Translation: AAK44453.1. BX842572 Genomic DNA. Translation: CAB06989.1.
PIR	D70961.
RefSeq	NP_214736.1. NC_000962.2. NP_334639.1. NC_002755.2.
3D structure databases
HSSP	HSSP built from PDB template 1MJ3 based on UniProtKB P14604.
ProteinModelPortal	P96404.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000000119; EBMYCP00000000119; EBMYCG00000000119. EBMYCT00000070782; EBMYCP00000068841; EBMYCG00000070777.
GeneID	886723. 923128.
GenomeReviews	Gene locus MT0232 in contig AE000516_GR. Gene locus Rv0222 in contig AL123456_GR.
KEGG	mtc:MT0232. mtu:Rv0222.
PATRIC	18122233. VBIMycTub22151_0251.
TIGR	MT0232.
Organism-specific databases
TubercuList	Rv0222.
Phylogenomic databases
GeneTree	EBGT00050000015506.
HOGENOM	HBG748731.
OMA	RIVANGP.
PhylomeDB	P96404.
ProtClustDB	PRK08252.
Family and domain databases
InterPro	IPR014748. Crontonase_C. IPR001753. Crotonase_core. IPR018376. Enoyl-CoA_hyd/isom_CS. [Graphical view]
Gene3D	G3DSA:1.10.12.10. Crontonase_C. 1 hit.
KO	K01692.
Pfam	PF00378. ECH. 1 hit. [Graphical view]
PROSITE	PS00166. ENOYL_COA_HYDRATASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P96404_MYCTU

Accession

Primary (citable) accession number: P96404
Secondary accession number(s): Q7DA88

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1997
Last sequence update:	May 1, 1997
Last modified:	December 14, 2011
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)