P96396 (P96396_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
PROBABLE FATTY-ACID-CoA LIGASE FADD4 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) EMBL CAB07009.1
EC=6.2.1.- EMBL CAB07009.1

Submitted name:
Substrate--CoA ligase, putative EMBL AAK44445.1

Gene names

Name:	fadD4 EMBL CAB07009.1
Ordered Locus Names:	MT0224, Rv0214

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	537 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Ligase EMBL CAB07009.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ligase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	P96396 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: D878F16EDEDC98C0	FASTA	537	58,889
	10 20 30 40 50 60 MPRGELYKRF RLVMGGIAPC GSGRRAATYP RRMQIRPYIG ADKPAVILYP SGTVISFDEL 70 80 90 100 110 120 EARANRLAHW FRQAGLREDD VVAILMENNE HVHAVMWAAR RSGLYYVPIN THLTASEAAY 130 140 150 160 170 180 IVDNSGAKAI VGSAALRETC HGLAEHLPGG LPDLLMLAGG GLVGWMTYPE CVADQPDTPI 190 200 210 220 230 240 EDEREGDLLQ YSSGTTGRPK GIKRELPHVS PDAAPGMMPA LLDFWMDADS VYLSPAPMYH 250 260 270 280 290 300 TAPSVWTMSA LAAGVTTVVM EKFDAEGALD AIQRYRVTHA QFVPAMFVRM LKLPEAVRNS 310 320 330 340 350 360 YDMSSLRRVI HAAAPCPVQI KEQMIHWWGP IIDEYYASSE ASGSTLITAE DWLTHPGSVG 370 380 390 400 410 420 KPIQGGVHIV GADGSELPPN QPGEIYFEGG YPFEYLNDPA KTAASRNKHG WVTVGDVGYL 430 440 450 460 470 480 DDDGYLFLTG RRHHMIISGG VNIYPQEAEN LLVAHPKVLD AAVFGVPDDE MGQRVMAAVQ 490 500 510 520 530 TVDSADANDQ FAGELLAWLR DRLSHFKCPR SIAFEPQLPR TDTGKLYKSG LVEKYSV

References

[1]

"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.

[2]

"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J., DeBoy R., Dodson R., Gwinn M., Haft D., Hickey E., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M., Salzberg S.L., Delcher A., Utterback T. , Weidman J., Khouri H., Gill J., Mikula A., Bishai W., Jacobs Jr W.R. Jr, Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000516 Genomic DNA. Translation: AAK44445.1. BX842572 Genomic DNA. Translation: CAB07009.1.
PIR	D70960.
RefSeq	NP_214728.1. NC_000962.2. NP_334631.1. NC_002755.2.
3D structure databases
HSSP	HSSP built from PDB template 1LCI based on UniProtKB P08659.
ProteinModelPortal	P96396.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000003321; EBMYCP00000003321; EBMYCG00000003319. EBMYCT00000071467; EBMYCP00000069526; EBMYCG00000071462.
GeneID	886737. 923119.
GenomeReviews	Gene locus MT0224 in contig AE000516_GR. Gene locus Rv0214 in contig AL123456_GR.
KEGG	mtc:MT0224. mtu:Rv0214.
PATRIC	18122217. VBIMycTub22151_0243.
TIGR	MT0224.
Organism-specific databases
TubercuList	Rv0214.
Phylogenomic databases
GeneTree	EBGT00050000015138.
HOGENOM	HBG547964.
OMA	PAMFTRM.
PhylomeDB	P96396.
ProtClustDB	PRK08276.
Family and domain databases
InterPro	IPR020845. AMP-binding_CS. IPR000873. AMP-dep_Synth/Lig. [Graphical view]
KO	K01897.
Pfam	PF00501. AMP-binding. 1 hit. [Graphical view]
PROSITE	PS00455. AMP_BINDING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P96396_MYCTU

Accession

Primary (citable) accession number: P96396
Secondary accession number(s): Q7DA95

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1997
Last sequence update:	May 1, 1997
Last modified:	December 14, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)