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Protein

Transcriptional regulatory protein RcsB

Gene

rcsB

Organism
Erwinia amylovora (Fire blight bacteria)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi168 – 187H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation, Two-component regulatory systemUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein RcsBUniRule annotation
Gene namesi
Name:rcsBUniRule annotationImported
OrganismiErwinia amylovora (Fire blight bacteria)Imported
Taxonomic identifieri552 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeErwinia

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei564-aspartylphosphateUniRule annotation1

Post-translational modificationi

Phosphorylated and activated by RcsD.UniRule annotation

Keywords - PTMi

PhosphoproteinUniRule annotation

Interactioni

Subunit structurei

Interacts with RcsD.UniRule annotation

Protein-protein interaction databases

STRINGi665029.EAMY_2342.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1P4WNMR-A129-215[»]
ProteinModelPortaliP96320.
SMRiP96320.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP96320.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 124Response regulatoryInterPro annotationAdd BLAST120
Domaini144 – 209HTH luxR-type DNA-bindingInterPro annotationAdd BLAST66

Sequence similaritiesi

Belongs to the RcsB family.UniRule annotation

Phylogenomic databases

eggNOGiENOG41068CG. Bacteria.
COG2197. LUCA.

Family and domain databases

CDDicd06170. LuxR_C_like. 1 hit.
Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_00981. RcsB. 1 hit.
InterProiView protein in InterPro
IPR011006. CheY-like_superfamily.
IPR030864. RcsB.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00196. GerE. 1 hit.
PF00072. Response_reg. 1 hit.
PRINTSiPR00038. HTHLUXR.
SMARTiView protein in SMART
SM00421. HTH_LUXR. 1 hit.
SM00448. REC. 1 hit.
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiView protein in PROSITE
PS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.

Sequencei

Sequence statusi: Complete.

P96320-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNLNVIIAD DHPIVLFGIR KSLEQIEWVN VVGEFEDSTA LINSLSKLDA
60 70 80 90 100
NVLVTDLSMP GEKYGDGITL IKYIKRHYPD LSIIVLTMNN NPAILSAVLD
110 120 130 140 150
LDIEGIVLKQ GAPTDLPKAL AALQKGKKYT PESVAKLLEK ISAGGYGDKR
160 170 180 190 200
LSPKESEVLR LFAEGFLVTE IAKKLNRSIK TISSQKKSAM MKLGVDNDIA
210
LLNYLSSVSM TPVDK
Length:215
Mass (Da):23,525
Last modified:May 1, 1997 - v1
Checksum:i0701410ED410D2A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09848 Genomic DNA. Translation: CAA70978.1.

Genome annotation databases

GeneIDi8914889.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09848 Genomic DNA. Translation: CAA70978.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1P4WNMR-A129-215[»]
ProteinModelPortaliP96320.
SMRiP96320.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi665029.EAMY_2342.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8914889.

Phylogenomic databases

eggNOGiENOG41068CG. Bacteria.
COG2197. LUCA.

Miscellaneous databases

EvolutionaryTraceiP96320.

Family and domain databases

CDDicd06170. LuxR_C_like. 1 hit.
Gene3Di1.10.10.10. 1 hit.
HAMAPiMF_00981. RcsB. 1 hit.
InterProiView protein in InterPro
IPR011006. CheY-like_superfamily.
IPR030864. RcsB.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
PfamiView protein in Pfam
PF00196. GerE. 1 hit.
PF00072. Response_reg. 1 hit.
PRINTSiPR00038. HTHLUXR.
SMARTiView protein in SMART
SM00421. HTH_LUXR. 1 hit.
SM00448. REC. 1 hit.
SUPFAMiSSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiView protein in PROSITE
PS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiP96320_ERWAM
AccessioniPrimary (citable) accession number: P96320
Entry historyiIntegrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: April 12, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.