Reviewed, UniProtKB/Swiss-Prot P96166 (NAGA_VIBFU)

Names and origin

Protein names

Recommended name:
    N-acetylglucosamine-6-phosphate deacetylase
    EC=3.5.1.25
Alternative name(s):
    GlcNAc 6-P deacetylase

Gene names

Name:

manD

Organism

Vibrio furnissii

Taxonomic identifier

29494 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.
Pathway	Amino-sugar metabolism; N-acetylneuraminate degradation; D-fructose 6-phosphate from N-acetylneuraminate: step 4/5.
Sequence similarities	Belongs to the nagA family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Molecular function	Hydrolase
Gene Ontology (GO)
Biological process	N-acetylglucosamine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	N-acetylglucosamine-6-phosphate deacetylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 399	399	N-acetylglucosamine-6-phosphate deacetylase		PRO_0000170919

Sequences

	Sequence		Length	Mass (Da)
	P96166-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: 82B1B9C3E5C99A37	FASTA	399	43,122
	10 20 30 40 50 60 MESKSHAHCF RAQRVLHGKQ WQQDAVVTVD ENGTISAIES YDGQRHADAI PLGPVDLMPG 70 80 90 100 110 120 LIDSHVHGSQ GCDVMDATHD SLNTMSRYFA TLGVTAFVAT TVTAPVAKIR AALAQVAKSK 130 140 150 160 170 180 HDGVDGAEIL GAYLEGPYFT EKNKGAHPTQ WFRELAVEEL EDWISYSDNQ LLKVALAPEK 190 200 210 220 230 240 TGALDAIRYL DAHGIHVMLG HSDADYEQVK AALAAGAKGI VHCYNGMRGL HHRDPGVVGA 250 260 270 280 290 300 GLLHPHCFVE MIADGHHVHP AAIDVAHRCC GSRMTLITDA MRATGMPDGQ YTLGEYQVDM 310 320 330 340 350 360 KQGVVMTSSG GLAGSTLTLL RGVKNIHRWL NVPIEQAWLM ASYTPAESLG IQHQLGSLEV 370 380 390 GKYASMVAVS SDFSIEKTWV KGRLVFDAAT SPRQEALCI

References

[1]	"Sugar transport by the marine chitinolytic bacterium Vibrio furnissii. Molecular cloning and analysis of the mannose/glucose permease." Bouma C.L., Roseman S. J. Biol. Chem. 271:33468-33475(1996) [PubMed: 8969210] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: SR1514.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U65015 Genomic DNA. Translation: AAC44683.1.
3D structure databases
HSSP	HSSP built from PDB template 1O12 based on UniProtKB Q9WZS1.
ModBase	Search...
Enzyme and pathway databases
BRENDA	3.5.1.25. 258010.
Family and domain databases
InterPro	IPR006680. Amidohydro_1. IPR003764. GlcNAc_6-P_deAcase. [Graphical view]
Pfam	PF01979. Amidohydro_1. 2 hits. [Graphical view]
ProDom	PD001248. Amidohydro_like. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00221. nagA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NAGA_VIBFU

Accession

Primary (citable) accession number: P96166

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	May 1, 1997
Last modified:	September 22, 2009
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)