Reviewed, UniProtKB/Swiss-Prot P96117 (TROB_TREPA)

Names and origin

Protein names

Recommended name:
    Zinc transport system ATP-binding protein troB

Gene names

Name:	troB
Ordered Locus Names:	TP_0164

Organism

Treponema pallidum [Complete proteome] [HAMAP]

Taxonomic identifier

160 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Treponema

Protein attributes

Sequence length	266 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of an ATP-driven transport system troABCD for zinc.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Ion transport Transport Zinc transport
Ligand	ATP-binding Nucleotide-binding Zinc
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	zinc ion transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 266	266	Zinc transport system ATP-binding protein troB		PRO_0000093025
Regions
	Domain	11 – 243	233	ABC transporter
	Nucleotide binding	43 – 50	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P96117-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: A7EB2DEDC4CF85B6	FASTA	266	29,360
	10 20 30 40 50 60 MAEISATAYA VQVDDLTLAY RQKPVLWDVD VRIPEGVIEA IIGPNGAGKS TLLKAIMGLL 70 80 90 100 110 120 PLASGEVRVF GRPFSKERRR VAYVPQRSAV DWDFPTTVFD VVLMGSYGSL GWILRPGKRE 130 140 150 160 170 180 KARAREAIEE VGMGAFLDRQ ISELSGGQQQ RVFLARALVQ DADLYFMDEP FQGVDAATEQ 190 200 210 220 230 240 AIVTLLKTLK GRGKTLLVVH HDLQTVAEYF DRVLLLNVRV IAEGAVVSAF TEEYVQRAYG 250 260 GRISSTLFPR GNKEDVHDAR AHASVL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification and transcriptional analysis of a Treponema pallidum operon encoding a putative ABC transport system, an iron-activated repressor protein homolog, and a glycolytic pathway enzyme homolog." Hardham J.M., Stamm L.V., Porcella S.F., Frye J.G., Barnes N.Y., Howell J.K., Mueller S.L., Radolf J.D., Weinstock G.M., Norris S.J. Gene 197:47-64(1997) [PubMed: 9332349] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Nichols.
[2]	"Complete genome sequence of Treponema pallidum, the syphilis spirochete." Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G., Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A., Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D., Khalak H.G., Richardson D.L., Howell J.K. , Chidambaram M., Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O., Venter J.C. Science 281:375-388(1998) [PubMed: 9665876] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nichols.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U55214 Genomic DNA. Translation: AAC45726.1. AE000520 Genomic DNA. Translation: AAC65154.1.
PIR	A71357.
RefSeq	NP_218603.1.
3D structure databases
SMR	P96117. Positions 11-227.
ModBase	Search...
Protein-protein interaction databases
IntAct	P96117. 4 interactions.
Protein family/group databases
TCDB	3.A.1.15.8. ATP-binding cassette (ABC) superfamily.
Genome annotation databases
GeneID	2611123.
GenomeReviews	Gene locus TP_0164 in contig AE000520_GR.
KEGG	tpa:TP0164.
NMPDR	fig|243276.1.peg.162.
TIGR	TP_0164.
Phylogenomic databases
HOGENOM	HBG758042.
OMA	ICVHHDL.
Enzyme and pathway databases
BioCyc	TPAL243276:TP_0164-MONOMER.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TROB_TREPA

Accession

Primary (citable) accession number: P96117

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 1, 2001
Last sequence update:	May 1, 1997
Last modified:	January 19, 2010
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)