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Protein

Alpha-amylase

Gene

amyA

Organism
Thermotoga maritima
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationImported, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

BRENDAi3.2.1.1. 10309.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotation (EC:3.2.1.1UniRule annotation)
Gene namesi
Name:amyAImported
OrganismiThermotoga maritimaImported
Taxonomic identifieri2336 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 553530Alpha-amylaseSequence analysisPRO_5004161705Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243274.TM1840.

Structurei

3D structure databases

ProteinModelPortaliP96107.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini57 – 422366AamyInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4108IUK. Bacteria.
COG0366. LUCA.
KOiK01176.

Family and domain databases

Gene3Di3.20.20.80. 2 hits.
InterProiIPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 2 hits.
PfamiPF00128. Alpha-amylase. 2 hits.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.

Sequencei

Sequence statusi: Complete.

P96107-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKPFLLLAF VFLLFLTSCF QTSMSQSLVS SNPHSNSTNT DGTSSNLEEV
60 70 80 90 100
KYPVVYEIFI RSFYDRDGNG VGDLNGVSQK VDYLKELGVD AVWFMPFNEA
110 120 130 140 150
VSYHGYDITD YYNVEKDYGT MEDLENMIQV LHENGIKVIM DLVINHTSDE
160 170 180 190 200
HPWFKDAVEN TTSSPYWDYY IMSLEDHSGQ DHWHWKINSK GQKVWYFGLF
210 220 230 240 250
GYNMPDLNHD SQKVREEVKK IVDFWISKGV DGFRIDAAKH IYGWSWDDGI
260 270 280 290 300
QESAEYFEWF RDYVLSKKPD AILVGEVFSG NTYDLSLYPI PVFNFALMYS
310 320 330 340 350
IRNYPEGQDG MIENNWVEES FLFLENHDLH RFFSHLQEHY KKFSESDYEF
360 370 380 390 400
IKKRAALWYF LIFTLKGSPV IYYGGEIGTR GFKWHGPVYD EPVREPMQWY
410 420 430 440 450
ASGTGEGQTF WTKEVYKNAG ITFGNADVDG CIYDDPYDGF SVEEQESDPK
460 470 480 490 500
SLLNFIRFIL NFRKDHDAIL NGDQTIFRDW KNLIAFYRES SNEKLLVVLN
510 520 530 540 550
PDPVWQNSFT FEENMTMILE VDFENFIWNE SNVSFSAGES FTVDPMKAYI

FKK
Length:553
Mass (Da):64,741
Last modified:July 1, 1997 - v2
Checksum:i30D05A4608B141A2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11359 Genomic DNA. Translation: CAA72194.1.
RefSeqiWP_004082384.1. NZ_CP011108.1.

Genome annotation databases

KEGGitmq:THMB_1883.
tmx:THMC_1883.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11359 Genomic DNA. Translation: CAA72194.1.
RefSeqiWP_004082384.1. NZ_CP011108.1.

3D structure databases

ProteinModelPortaliP96107.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243274.TM1840.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGitmq:THMB_1883.
tmx:THMC_1883.

Phylogenomic databases

eggNOGiENOG4108IUK. Bacteria.
COG0366. LUCA.
KOiK01176.

Enzyme and pathway databases

BRENDAi3.2.1.1. 10309.

Family and domain databases

Gene3Di3.20.20.80. 2 hits.
InterProiIPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR006047. Glyco_hydro_13_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 2 hits.
PfamiPF00128. Alpha-amylase. 2 hits.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiP96107_THEMT
AccessioniPrimary (citable) accession number: P96107
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: July 1, 1997
Last modified: May 11, 2016
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.