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P96000

- GPT_SULSO

UniProt

P96000 - GPT_SULSO

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Protein

Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

Gene

gnpTA

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.

Enzyme regulationi

Inhibited by tunicamycin.By similarity

GO - Molecular functioni

  1. phospho-N-acetylmuramoyl-pentapeptide-transferase activity Source: InterPro
  2. transferase activity, transferring glycosyl groups Source: UniProtKB-KW
  3. UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciSSOL273057:GCH2-59-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC:2.7.8.15)
Alternative name(s):
GlcNAc-1-P transferase
Short name:
G1PT
Short name:
GPT
N-acetylglucosamine-1-phosphate transferase
Gene namesi
Name:gnpTA
Ordered Locus Names:SSO0060
ORF Names:C05011
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001974: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei5 – 2521HelicalSequence AnalysisAdd
BLAST
Transmembranei46 – 6621HelicalSequence AnalysisAdd
BLAST
Transmembranei76 – 9621HelicalSequence AnalysisAdd
BLAST
Transmembranei102 – 12221HelicalSequence AnalysisAdd
BLAST
Transmembranei123 – 14321HelicalSequence AnalysisAdd
BLAST
Transmembranei160 – 18021HelicalSequence AnalysisAdd
BLAST
Transmembranei186 – 20621HelicalSequence AnalysisAdd
BLAST
Transmembranei222 – 24221HelicalSequence AnalysisAdd
BLAST
Transmembranei295 – 31521HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 322322Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferasePRO_0000108767Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273057.SSO0060.

Structurei

3D structure databases

ProteinModelPortaliP96000.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 4 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0472.
HOGENOMiHOG000227679.
InParanoidiP96000.
KOiK01001.
OMAiRVGWADQ.

Family and domain databases

InterProiIPR000715. Glycosyl_transferase_4.
[Graphical view]
PANTHERiPTHR22926. PTHR22926. 1 hit.
PfamiPF00953. Glycos_transf_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P96000-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRILAILLPI LISFFISYIT TVWVIRQAKK SRFVGKDINK PDKPEIPLLG
60 70 80 90 100
GIGIIAGFIA GSFSLLLTDV RSERVIPAVI LSSLLIAFLG LLDDIFNVRQ
110 120 130 140 150
SVRAFLPIFA SVPLIVYSVG HSIISIPFLG PINFGIFYYI IIIPFALTIT
160 170 180 190 200
SNAFNMLEGL NGLGVGMGII MLSALAYIGL THTGPTYQAG LIALSAIFSL
210 220 230 240 250
SAFLIFNKYP AKIFPGNVGT YFIGALIGAI GIAGFMYTAL AILYIPYVVE
260 270 280 290 300
FILKLRTNFK GVSFGKVDSS GRLYWDEKPH SLTHIVMKMG RFKEYQVVII
310 320
LWGMEAIFAV IAVILQTTTI VI
Length:322
Mass (Da):35,252
Last modified:May 1, 1997 - v1
Checksum:i41F58B03A3269F7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y08257 Genomic DNA. Translation: CAA69542.1.
AE006641 Genomic DNA. Translation: AAK40422.1.
PIRiS75428.
RefSeqiNP_341632.1. NC_002754.1.
WP_009988861.1. NC_002754.1.

Genome annotation databases

EnsemblBacteriaiAAK40422; AAK40422; SSO0060.
GeneIDi1455313.
KEGGisso:SSO0060.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y08257 Genomic DNA. Translation: CAA69542.1 .
AE006641 Genomic DNA. Translation: AAK40422.1 .
PIRi S75428.
RefSeqi NP_341632.1. NC_002754.1.
WP_009988861.1. NC_002754.1.

3D structure databases

ProteinModelPortali P96000.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273057.SSO0060.

Protocols and materials databases

DNASUi 1455313.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAK40422 ; AAK40422 ; SSO0060 .
GeneIDi 1455313.
KEGGi sso:SSO0060.

Phylogenomic databases

eggNOGi COG0472.
HOGENOMi HOG000227679.
InParanoidi P96000.
KOi K01001.
OMAi RVGWADQ.

Enzyme and pathway databases

BioCyci SSOL273057:GCH2-59-MONOMER.

Family and domain databases

InterProi IPR000715. Glycosyl_transferase_4.
[Graphical view ]
PANTHERi PTHR22926. PTHR22926. 1 hit.
Pfami PF00953. Glycos_transf_4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Organizational characteristics and information content of an archaeal genome: 156 kb of sequence from Sulfolobus solfataricus P2."
    Sensen C.W., Klenk H.-P., Singh R.K., Allard G., Chan C.C.-Y., Liu Q.Y., Penny S.L., Young F., Schenk M.E., Gaasterland T., Doolittle W.F., Ragan M.A., Charlebois R.L.
    Mol. Microbiol. 22:175-191(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

Entry informationi

Entry nameiGPT_SULSO
AccessioniPrimary (citable) accession number: P96000
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 29, 2001
Last sequence update: May 1, 1997
Last modified: November 26, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3