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Protein

Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

Gene

gnpTA

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.

Enzyme regulationi

Inhibited by tunicamycin.By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC:2.7.8.15)
Alternative name(s):
GlcNAc-1-P transferase
Short name:
G1PT
Short name:
GPT
N-acetylglucosamine-1-phosphate transferase
Gene namesi
Name:gnpTA
Ordered Locus Names:SSO0060
ORF Names:C05011
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001974 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei5 – 25HelicalSequence analysisAdd BLAST21
Transmembranei46 – 66HelicalSequence analysisAdd BLAST21
Transmembranei76 – 96HelicalSequence analysisAdd BLAST21
Transmembranei102 – 122HelicalSequence analysisAdd BLAST21
Transmembranei123 – 143HelicalSequence analysisAdd BLAST21
Transmembranei160 – 180HelicalSequence analysisAdd BLAST21
Transmembranei186 – 206HelicalSequence analysisAdd BLAST21
Transmembranei222 – 242HelicalSequence analysisAdd BLAST21
Transmembranei295 – 315HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001087671 – 322Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferaseAdd BLAST322

Interactioni

Protein-protein interaction databases

STRINGi273057.SSO0060.

Structurei

3D structure databases

ProteinModelPortaliP96000.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 4 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiarCOG03199. Archaea.
COG0472. LUCA.
HOGENOMiHOG000227679.
InParanoidiP96000.
KOiK01001.
OMAiYIVELMA.

Family and domain databases

InterProiIPR000715. Glycosyl_transferase_4.
[Graphical view]
PANTHERiPTHR22926. PTHR22926. 1 hit.
PfamiPF00953. Glycos_transf_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P96000-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRILAILLPI LISFFISYIT TVWVIRQAKK SRFVGKDINK PDKPEIPLLG
60 70 80 90 100
GIGIIAGFIA GSFSLLLTDV RSERVIPAVI LSSLLIAFLG LLDDIFNVRQ
110 120 130 140 150
SVRAFLPIFA SVPLIVYSVG HSIISIPFLG PINFGIFYYI IIIPFALTIT
160 170 180 190 200
SNAFNMLEGL NGLGVGMGII MLSALAYIGL THTGPTYQAG LIALSAIFSL
210 220 230 240 250
SAFLIFNKYP AKIFPGNVGT YFIGALIGAI GIAGFMYTAL AILYIPYVVE
260 270 280 290 300
FILKLRTNFK GVSFGKVDSS GRLYWDEKPH SLTHIVMKMG RFKEYQVVII
310 320
LWGMEAIFAV IAVILQTTTI VI
Length:322
Mass (Da):35,252
Last modified:May 1, 1997 - v1
Checksum:i41F58B03A3269F7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y08257 Genomic DNA. Translation: CAA69542.1.
AE006641 Genomic DNA. Translation: AAK40422.1.
PIRiS75428.
RefSeqiWP_009988861.1. NC_002754.1.

Genome annotation databases

EnsemblBacteriaiAAK40422; AAK40422; SSO0060.
GeneIDi27426356.
KEGGisso:SSO0060.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y08257 Genomic DNA. Translation: CAA69542.1.
AE006641 Genomic DNA. Translation: AAK40422.1.
PIRiS75428.
RefSeqiWP_009988861.1. NC_002754.1.

3D structure databases

ProteinModelPortaliP96000.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273057.SSO0060.

Protocols and materials databases

DNASUi1455313.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK40422; AAK40422; SSO0060.
GeneIDi27426356.
KEGGisso:SSO0060.

Phylogenomic databases

eggNOGiarCOG03199. Archaea.
COG0472. LUCA.
HOGENOMiHOG000227679.
InParanoidiP96000.
KOiK01001.
OMAiYIVELMA.

Miscellaneous databases

PROiP96000.

Family and domain databases

InterProiIPR000715. Glycosyl_transferase_4.
[Graphical view]
PANTHERiPTHR22926. PTHR22926. 1 hit.
PfamiPF00953. Glycos_transf_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGPT_SULSO
AccessioniPrimary (citable) accession number: P96000
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 29, 2001
Last sequence update: May 1, 1997
Last modified: November 2, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.