Reviewed, UniProtKB/Swiss-Prot P95931 (PGP2_SULSO)

Names and origin

Protein names

Recommended name:
    Phosphoglycolate phosphatase 2
      Short name=PGPase 2
      Short name=PGP 2
    EC=3.1.3.18

Gene names

Ordered Locus Names:	SSO2157
ORF Names:	C01033

Organism

Sulfolobus solfataricus [Complete proteome] [HAMAP]

Taxonomic identifier

2287 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	233 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the dephosphorylation of 2-phosphoglycolate By similarity.
Catalytic activity	2-phosphoglycolate + H2O = glycolate + phosphate. HAMAP MF_01419
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the archaeal SPP-like hydrolase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycolate phosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 233	233	Phosphoglycolate phosphatase 2 HAMAP MF_01419		PRO_0000146729
Sites
	Active site	13	1	Nucleophile By similarity
	Metal binding	13	1	Magnesium By similarity
	Metal binding	15	1	Magnesium By similarity
	Metal binding	174	1	Magnesium By similarity
	Metal binding	178	1	Magnesium By similarity
	Binding site	152	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	P95931-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: 5E3AE64515CAAD90	FASTA	233	26,215
	10 20 30 40 50 60 MDIGSNEILV ASDYDRTLAS EENNFVISPI VSQKVNEFSK KYKFVVVTGR EKKFIDKLAV 70 80 90 100 110 120 GLKPTAWILE NGSLILFNDR EFVLCEKSWF ERDRKKIIEI LDNLKVRYSI GRIILYVDGY 130 140 150 160 170 180 GSKLDMLSEI EKYGRIEVNR NDAMILPKGV DKGVGVLKFK ELTGFKGKII ALGDSENDYA 190 200 210 220 230 LFRVADIKVA VANAIPQIKE IADIVTENPN GLGVVEILDK ILSGNFGKEV DIY

References

[1]

"The complete genome of the crenarchaeon Sulfolobus solfataricus P2." She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J., Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G., Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J., Medina N., Peng X. , Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C., Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T., Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J. Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001) [PubMed: 11427726] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Y08256 Genomic DNA. Translation: CAA69435.1. AE006641 Genomic DNA. Translation: AAK42333.1.
PIR	S74064.
RefSeq	NP_343543.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1453660.
GenomeReviews	Gene locus SSO2157 in contig AE006641_GR.
KEGG	sso:SSO2157.
NMPDR	fig|273057.1.peg.1966.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P95931.
OMA	P95931. NDAMILP.
Enzyme and pathway databases
BioCyc	SSOL273057:SSO2157-MON.
BRENDA	3.1.3.18. 2070.
Family and domain databases
HAMAP	MF_01419. [Tree]
InterPro	IPR013200. HAD-SF_hydro-like_3. IPR006379. HAD-SF_hydro_IIB. IPR006382. SPPlik_hydro_arc. IPR006378. Suc_phosP. [Graphical view]
Pfam	PF08282. Hydrolase_3. 1 hit. [Graphical view]
TIGRFAMs	TIGR01484. HAD-SF-IIB. 1 hit. TIGR01487. SPP-like. 1 hit. TIGR01482. SPP-subfamily. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PGP2_SULSO

Accession

Primary (citable) accession number: P95931

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
Last sequence update:	May 1, 1997
Last modified:	June 16, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)