Reviewed, UniProtKB/Swiss-Prot P95862 (DLHH_SULSO)

Names and origin

Protein names

Recommended name:
    Putative carboxymethylenebutenolidase
    EC=3.1.1.45
Alternative name(s):
    Dienelactone hydrolase
      Short name=DLH

Gene names

Ordered Locus Names:	SSO2087
ORF Names:	C06015, C31_045

Organism

Sulfolobus solfataricus [Complete proteome] [HAMAP]

Taxonomic identifier

2287 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	4-carboxymethylenebut-2-en-4-olide + H2O = 4-oxohex-2-enedioate.
Sequence similarities	Belongs to the dienelactone hydrolase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	carboxymethylenebutenolidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 257	257	Putative carboxymethylenebutenolidase		PRO_0000161584
Sites
	Active site	148	1	By similarity
	Active site	195	1	By similarity
	Active site	226	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	P95862-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: B2BD7FACD6126382	FASTA	257	29,016
	10 20 30 40 50 60 MEKEIFYDSD GAKIRAFLAT PENPKLAVIV IHEIWGLNDN IKDISRRLAN EGYMALAPQL 70 80 90 100 110 120 YTRNEDVLNE GNIQNVMMKV WSIPPEKRND PNSYQQIMSA LDEKGKKVAE LLVLNRQKTE 130 140 150 160 170 180 EQMIKDAIKA YEYVSSQGVK KIVSMGFCMG GGLAFQLATE VPLDGTIVFY GRNPQPLEAI 190 200 210 220 230 240 QKIKGPILGL YAGEDPPIDA GLPDLISAII KYKKDLELKI YPGAYHAFFN DRGRSYNKEA 250 AEDAWERVKS FLRRVSK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Organizational characteristics and information content of an archaeal genome: 156 kb of sequence from Sulfolobus solfataricus P2." Sensen C.W., Klenk H.-P., Singh R.K., Allard G., Chan C.C.-Y., Liu Q.Y., Penny S.L., Young F., Schenk M.E., Gaasterland T., Doolittle W.F., Ragan M.A., Charlebois R.L. Mol. Microbiol. 22:175-191(1996) [PubMed: 8899719] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.
[2]	"The complete genome of the crenarchaeon Sulfolobus solfataricus P2." She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J., Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G., Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J., Medina N., Peng X. , Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C., Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T., Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J. Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001) [PubMed: 11427726] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y08256 Genomic DNA. Translation: CAA69498.1. AE006641 Genomic DNA. Translation: AAK42266.1.
PIR	S73082.
RefSeq	NP_343476.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1453593.
GenomeReviews	Gene locus SSO2087 in contig AE006641_GR.
KEGG	sso:SSO2087.
NMPDR	fig|273057.1.peg.1899.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG673102.
OMA	AFAPQLY.
PhylomeDB	P95862.
Enzyme and pathway databases
BioCyc	SSOL273057:SSO2087-MONOMER.
BRENDA	3.1.1.45. 2070.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

DLHH_SULSO

Accession

Primary (citable) accession number: P95862

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	May 1, 1997
Last modified:	February 9, 2010
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)