Reviewed,
UniProtKB/Swiss-Prot P95646 (TRPE_RHOS4)
Last modified
February 9, 2010.
Version 65.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Anthranilate synthase component 1 EC=4.1.3.27 Alternative name(s): Anthranilate synthase component I | ||||||
| Gene names |
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| Organism | Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158) [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 272943 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter |
Protein attributes
| Sequence length | 500 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | Chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate. |
| Pathway | Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5. |
| Subunit structure | Tetramer of two components I and two components II By similarity. |
| Miscellaneous | Component I catalyzes the formation of anthranilate using ammonia rather than glutamine, whereas component II provides glutamine amidotransferase activity. |
| Sequence similarities | Belongs to the anthranilate synthase component I family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis |
| Molecular function | Lyase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | anthranilate synthase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | Rosanas A., Barbe J., Gibert I. Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "Complete sequence of chromosome 1 of Rhodobacter sphaeroides 2.4.1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | Y09072 Genomic DNA. Translation: CAA70293.1. CP000143 Genomic DNA. Translation: ABA78154.1. Different initiation. |
| RefSeq | YP_352055.1. |
3D structure databases | |
| SMR | P95646. Positions 25-488. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | P95646. |
Genome annotation databases | |
| GeneID | 3719337. |
| GenomeReviews | Gene locus RHOS4_05860 in contig CP000143_GR. |
| KEGG | rsp:RSP_2004. |
| NMPDR | fig|272943.3.peg.665. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0147. |
| HOGENOM | HBG507440. |
| PhylomeDB | P95646. |
Enzyme and pathway databases | |
| BioCyc | RSPH272943:RSP_2004-MONOMER. |
Family and domain databases | |
| InterPro | IPR005801. ADC_synthase. IPR006805. Anth_synth_I_N. IPR005256. Anth_synthI. IPR019999. Anthranilate_synth_I_C. IPR015890. Chorismate-bd_C. [Graphical view] |
| Gene3D | G3DSA:3.60.120.10. TRPE_1_chor_bd. 1 hit. |
| PANTHER | PTHR11236. TRPE_1_chor_bd. 1 hit. |
| Pfam | PF04715. Anth_synt_I_N. 1 hit. PF00425. Chorismate_bind. 1 hit. [Graphical view] |
| PRINTS | PR00095. ANTSNTHASEI. |
| TIGRFAMs | TIGR00564. trpE_most. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | TRPE_RHOS4 | ||||||||
| Accession | Primary (citable) accession number: P95646 Secondary accession number(s): Q3J4Y0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


