Reviewed, UniProtKB/Swiss-Prot P95607 (CATA_RHOOP)

Names and origin

Protein names

Recommended name:
    Catechol 1,2-dioxygenase
    EC=1.13.11.1
Alternative name(s):
    1,2-CTD

Gene names

Name:

catA

Organism

Rhodococcus opacus (Nocardia opaca)

Taxonomic identifier

37919 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus

Protein attributes

Sequence length	270 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Catechol + O(2) = cis,cis-muconate.
Cofactor	Binds 1 Fe(3+) ion per subunit.
Sequence similarities	Belongs to the intradiol ring-cleavage dioxygenase family.

Ontologies

Keywords
Biological process	Aromatic hydrocarbons catabolism
Ligand	Iron Metal-binding
Molecular function	Dioxygenase Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	aromatic compound catabolic process Inferred from electronic annotation. Source: UniProtKB-KW catechol metabolic process Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	catechol 1,2-dioxygenase activity Inferred from electronic annotation. Source: InterPro ferric iron binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	‹1 – 270	›270	Catechol 1,2-dioxygenase		PRO_0000085084
Sites
	Metal binding	152	1	Iron By similarity
	Metal binding	186	1	Iron By similarity
	Metal binding	210	1	Iron By similarity
	Metal binding	212	1	Iron By similarity
Experimental info
	Non-terminal residue	1	1

Sequences

	Sequence		Length	Mass (Da)
	P95607-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: BCD5BE5B8365115A	FASTA	270	29,704
	10 20 30 40 50 60 GSGSAATDKF KAERATADTS PERLAAIAKD ALGALNDVIL KHGVTYPEYR VFKQWLIDVG 70 80 90 100 110 120 EGGEWPLFLD VFIEHSVEEV LARSRKGTMG SIEGPYYIEN SPELPSKCTL PMREEDEKIT 130 140 150 160 170 180 PLVFSGQVTD LDGNGLAGAK VELWHADNDG YYSQFAPHLP EWNLRGTIIA DEEGRYEITT 190 200 210 220 230 240 IQPAPYQIPT DGPTGQFIEA QNGHPWRPAH LHLIVSAPGK ESVTTQLYFK GGEWIDSDVA 250 260 270 SATKPELILD PKTGDDGKNY VTYNFVLDPA

References

[1]	"Characterization of catechol catabolic genes from Rhodococcus erythropolis 1CP." Eulberg D., Golovleva L.A., Schloemann M. J. Bacteriol. 179:370-381(1997) [PubMed: 8990288] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 113-132 AND 195-203. Strain: 1CP.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X99622 Genomic DNA. Translation: CAA67941.1.
3D structure databases
HSSP	HSSP built from PDB template 1DMH based on UniProtKB P07773.
ModBase	Search...
Family and domain databases
InterPro	IPR007535. Catechol_dOase_N. IPR012800. Cchol_dOase_actb. IPR000627. Intradiol_dOase_C. IPR015889. Intradiol_dOase_core. [Graphical view]
Gene3D	G3DSA:2.60.130.10. Intradiol_dOase_core. 1 hit.
Pfam	PF00775. Dioxygenase_C. 1 hit. PF04444. Dioxygenase_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR02438. catachol_actin. 1 hit.
PROSITE	PS00083. INTRADIOL_DIOXYGENAS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CATA_RHOOP

Accession

Primary (citable) accession number: P95607

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	May 1, 1997
Last modified:	November 25, 2008
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)