Reviewed,
UniProtKB/Swiss-Prot P95544 (DHE4_PRERU)
Last modified
January 19, 2010.
Version 46.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: NAD(P)-specific glutamate dehydrogenase Short name=NADP-GDH EC=1.4.1.3 Alternative name(s): NAD(P)H-dependent glutamate dehydrogenase | ||
| Gene names |
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| Organism | Prevotella ruminicola (Bacteroides ruminicola) | ||
| Taxonomic identifier | 839 [NCBI] | ||
| Taxonomic lineage | Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Prevotellaceae › Prevotella |
Protein attributes
| Sequence length | 444 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H. |
| Subunit structure | Homohexamer By similarity. |
| Sequence similarities | Belongs to the Glu/Leu/Phe/Val dehydrogenases family. |
Ontologies
| Keywords | |
|---|---|
| Ligand | NAD NADP |
| Molecular function | Oxidoreductase |
| Gene Ontology (GO) | |
| Biological process | cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro oxidation reductionInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | binding Inferred from electronic annotation. Source: InterPro glutamate dehydrogenase [NAD(P)+] activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "The NAD(P)H-dependent glutamate dehydrogenase activities of Prevotella ruminicola B(1)4 can be attributed to one enzyme (GdhA), and gdhA expression is regulated in response to the nitrogen source available for growth." Wen Z., Morrison M. Appl. Environ. Microbiol. 62:3826-3833(1996) [PubMed: 8837439] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: B14. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | U82240 Genomic DNA. Translation: AAB40142.1. |
| PIR | T10487. |
3D structure databases | |
| SMR | P95544. Positions 3-444. |
| ModBase | Search... |
Enzyme and pathway databases | |
| BRENDA | 1.4.1.3. 97798. |
Family and domain databases | |
| InterPro | IPR006095. Glu/Leu/Phe/Val_DH. IPR006096. Glu/Leu/Phe/Val_DH_C. IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom. IPR014362. Glu_DH. IPR016040. NAD(P)-bd_dom. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| PANTHER | PTHR11606:SF2. GLFV_DH. 1 hit. |
| Pfam | PF00208. ELFV_dehydrog. 1 hit. PF02812. ELFV_dehydrog_N. 1 hit. [Graphical view] |
| PIRSF | PIRSF000185. Glu_DH. 1 hit. |
| PRINTS | PR00082. GLFDHDRGNASE. |
| SMART | SM00839. ELFV_dehydrog. 1 hit. [Graphical view] |
| PROSITE | PS00074. GLFV_DEHYDROGENASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | DHE4_PRERU | ||||||||
| Accession | Primary (citable) accession number: P95544 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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