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Protein

Catalase HPII

Gene

katE

Organism
Pseudomonas putida (Arthrobacter siderocapsulatus)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.

Catalytic activityi

2 H2O2 = O2 + 2 H2O.PROSITE-ProRule annotation

Cofactori

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei92 – 921PROSITE-ProRule annotation
Active sitei165 – 1651PROSITE-ProRule annotation
Metal bindingi379 – 3791Iron (heme axial ligand)By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase, Peroxidase

Keywords - Biological processi

Hydrogen peroxide

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Catalase HPII (EC:1.11.1.6)
Gene namesi
Name:katE
Synonyms:catC
OrganismiPseudomonas putida (Arthrobacter siderocapsulatus)
Taxonomic identifieri303 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 711711Catalase HPIIPRO_0000084973Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi160488.PP_0115.

Structurei

3D structure databases

ProteinModelPortaliP95539.
SMRiP95539. Positions 24-711.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the catalase family. HPII subfamily.Curated

Phylogenomic databases

eggNOGiCOG0753. LUCA.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024712. Catalase_clade2.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
IPR029062. Class_I_gatase-like.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038927. Catalase_clade2. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF52317. SSF52317. 1 hit.
SSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P95539-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSKKTDAPK QSEAAGTQTP DRANTNAKLQ SLETFRSDAT GQALRTNQGV
60 70 80 90 100
KIADNQNSLK AGARGPSLLE DFIMREKITH FDHERIPERI VHARGTGAHG
110 120 130 140 150
YFQSYGNHAD LTKAGFLQDP DKITPVFVRF STVQGPRGSG DTVRDVRGFA
160 170 180 190 200
VKFYTDEGNF DLVGNNMPVF FIQDAIKFPD FVHAVKPEPH NEIPTGGSAH
210 220 230 240 250
DTFWDFVSLV PESAHMVMWA MSDRAIPRSL RMMEGFGVHT FRLINAEGVA
260 270 280 290 300
SFVKFHWKPR QGVHSLLWDE AQKLAGKDTD FQRRDLWEAI ENGDYPEWEL
310 320 330 340 350
GVQIVPEADE HKFDFDLLDP TKIIPEELVP VTPLGKMVLN RNPDNFFAEV
360 370 380 390 400
EQVAFCPGHI VPGIDFTNDP LLQGRLFSYT DTQISRLGGP NFHQIPINRP
410 420 430 440 450
VAPNHNNQRD ALHQHVVHKG RASYEPNSID GGWPKETPAA AQDGGFESYQ
460 470 480 490 500
ERIDAHKIRQ RSESFGDHFS QARLFFQSMS PTEQQHIIKA YSFELGKVER
510 520 530 540 550
EHIRAREVNE ILANIDLKLA AAVAANLGLP APKAGTVQVK GSQLAQSPAL
560 570 580 590 600
SQMNHPGSVG IKGRKIAVLV ANGVDAASVD KLIKALEAHS ARPMLLGPTS
610 620 630 640 650
APVKATDGKQ LPVEASMEGM PSIMFDGIVV PSGKASTDAL AASGLAKHFL
660 670 680 690 700
LEGYKHLKAM VLTKELATGL GLKEDKGLLL ADDQKAVDAF VKAVEGHRVW
710
EREAAAEAVP A
Length:711
Mass (Da):78,129
Last modified:May 1, 1997 - v1
Checksum:i0D134B629B203C21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82622 Genomic DNA. Translation: AAB40866.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82622 Genomic DNA. Translation: AAB40866.1.

3D structure databases

ProteinModelPortaliP95539.
SMRiP95539. Positions 24-711.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi160488.PP_0115.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiCOG0753. LUCA.

Family and domain databases

Gene3Di2.40.180.10. 1 hit.
3.40.50.880. 1 hit.
InterProiIPR018028. Catalase.
IPR020835. Catalase-like_dom.
IPR024708. Catalase_AS.
IPR024712. Catalase_clade2.
IPR011614. Catalase_core.
IPR002226. Catalase_haem_BS.
IPR010582. Catalase_immune_responsive.
IPR029062. Class_I_gatase-like.
[Graphical view]
PANTHERiPTHR11465. PTHR11465. 1 hit.
PfamiPF00199. Catalase. 1 hit.
PF06628. Catalase-rel. 1 hit.
[Graphical view]
PIRSFiPIRSF038927. Catalase_clade2. 1 hit.
PRINTSiPR00067. CATALASE.
SMARTiSM01060. Catalase. 1 hit.
[Graphical view]
SUPFAMiSSF52317. SSF52317. 1 hit.
SSF56634. SSF56634. 1 hit.
PROSITEiPS00437. CATALASE_1. 1 hit.
PS00438. CATALASE_2. 1 hit.
PS51402. CATALASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCATE_PSEPU
AccessioniPrimary (citable) accession number: P95539
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 1, 1997
Last modified: November 11, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.