P95354 (ARSC_NEIGO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative arsenate reductase
EC=1.20.4.1

Gene names

Name:

arsC

Organism

Neisseria gonorrhoeae

Taxonomic identifier

485 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria

Protein attributes

Sequence length	102 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Reduction of arsenate [As(V)] to arsenite [As(III)] Potential.
Catalytic activity	Arsenate + glutaredoxin = arsenite + glutaredoxin disulfide + H2O.
Sequence similarities	Belongs to the ArsC family.

Ontologies

Keywords
Biological process	Arsenical resistance
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological_process	response to arsenic-containing substance Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	arsenate reductase (glutaredoxin) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 102	102	Putative arsenate reductase		PRO_0000162540

Sequences

	Sequence		Length	Mass (Da)
	P95354 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: E015371DA3FCED71	FASTA	102	11,413
	10 20 30 40 50 60 MSEIKIFHNP RCSKSRAAVS LLEERGIAAE AVKYLDTPPD LSELKDIFNK LGLESARGMM 70 80 90 100 RVKDDLYKEL GLDNPDLDND ALLRAIADHP ALLERPIVLG KR

References

[1]	"Genomic, transcriptional and phenotypic analysis of ftsE and ftsX of Neisseria gonorrhoeae." Bernatchez S., Francis F.M., Salimnia H., Beveridge T.J., Li H., Dillon J.-A.R. DNA Res. 7:75-81(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: CH811.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U76418 Genomic DNA. Translation: AAB36522.1.
3D structure databases
ProteinModelPortal	P95354.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.40.30.10. 1 hit.
InterPro	IPR006659. Arsenate_reductase. IPR006660. Arsenate_reductase-like. IPR012336. Thioredoxin-like_fold. [Graphical view]
Pfam	PF03960. ArsC. 1 hit. [Graphical view]
SUPFAM	SSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMs	TIGR00014. arsC. 1 hit.
PROSITE	PS51353. ARSC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ARSC_NEIGO

Accession

Primary (citable) accession number: P95354

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	May 1, 1997
Last modified:	April 3, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program