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Protein
Submitted name:

Oxygenase

Gene

Rv1937

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

2Fe-2SUniRule annotationSAAS annotation, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
OxygenaseImported
Submitted name:
Possible oxygenaseImported
Gene namesi
Ordered Locus Names:Rv1937Imported
ORF Names:LH57_10540Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Organism-specific databases

TubercuListiRv1937.

Subcellular locationi

GO - Cellular componenti

  • cell wall Source: MTBBASE
  • cytosol Source: MTBBASE
  • plasma membrane Source: MTBBASE
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv1937.

Structurei

3D structure databases

SMRiP95277. Positions 5-338, 362-393, 481-553, 671-709.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 95922Fe-2S ferredoxin-typeInterPro annotationAdd
BLAST
Domaini102 – 204103FAD-binding FR-typeInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 2Fe-2S ferredoxin-type domain.UniRule annotation
Contains FAD-binding FR-type domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0543. LUCA.
HOGENOMiHOG000049240.
OMAiASGKNTH.
OrthoDBiEOG6MPWTK.
PhylomeDBiP95277.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR001041. 2Fe-2S_ferredoxin-type.
IPR006058. 2Fe2S_fd_BS.
IPR012675. Beta-grasp_dom.
IPR023753. FAD/NAD-binding_dom.
IPR017927. Fd_Rdtase_FAD-bd.
IPR008333. OxRdtase_FAD-bd_dom.
IPR001433. OxRdtase_FAD/NAD-bd.
IPR001221. Phe_hydroxylase.
IPR017938. Riboflavin_synthase-like_b-brl.
[Graphical view]
PfamiPF00970. FAD_binding_6. 1 hit.
PF00111. Fer2. 1 hit.
PF00175. NAD_binding_1. 1 hit.
[Graphical view]
PRINTSiPR00410. PHEHYDRXLASE.
SUPFAMiSSF51905. SSF51905. 2 hits.
SSF54292. SSF54292. 1 hit.
SSF63380. SSF63380. 1 hit.
PROSITEiPS00197. 2FE2S_FER_1. 1 hit.
PS51085. 2FE2S_FER_2. 1 hit.
PS51384. FAD_FR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P95277-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVRQVTVGY SDGTHKTMPV RCDQTVLDAA EEHGVAIVNE CQSGICGTCV
60 70 80 90 100
ATCTAGRYQM GRTEGLSDVE RAARKILTCQ TFVTSDCRIE LQYPVDDNAA
110 120 130 140 150
LLVTGDGVVT AVELVSPSTA ILRVDTSGMA GALRYRAGQF AQLQVPGTNV
160 170 180 190 200
WRNYSYAHPA DGRGECEFII RLLPDGVMSN YLRDRAQPGD HIALRCSKGS
210 220 230 240 250
FYLRPIVRPV ILVAGGTGLS AILAMAQSLD ADVAHPVYLL YGVERTEDLC
260 270 280 290 300
KLDELTELRR RVGRLEVHVV VARPDPDWDG RTGLVTDLLD ERMLASGDAD
310 320 330 340 350
VYLCGPVAMV DAARTWLDHN GFHRVGLYYE KFVASGAARR RTPARLDYAG
360 370 380 390 400
VDIAEVCRRG RGTAVVIGGS IAGIAAAKML SETFDRVIVL EKDGPHRRRE
410 420 430 440 450
GRPGAAQGWH LHHLLTAGQI ELERIFPGIV DDMVREGAFK VDMAAQYRIR
460 470 480 490 500
LGGTWKKPGT SDIEIVCAGR PLLEWCVRRR LDDEPRIDFR YESEVADLAF
510 520 530 540 550
DRANNAIVGV AVDNGDADGG DGLQVVPAEF VVDASGKNTR VPEFLERLGV
560 570 580 590 600
GAPEAEQDII NCFYSTMQHR VPPERRWQDK VMVICYAYRP FEDTYAAQYY
610 620 630 640 650
TDSSRTILST SLVAYNCYSP PRTAREFRAF ADLMPSPVIG ENIDGLEPAS
660 670 680 690 700
PIYNFRYPNM LRLRYEKKRN LPRALLAVGD AYTSADPVSG LGMSLALKEV
710 720 730 740 750
REMQALLAKY GAGHRDLPRR YYRAIAKMAD TAWFVIREQN LRFDWMKDVD
760 770 780 790 800
KKRPFYFGVL TWYMDRVLEL VHDDLDAYRE FLAVVHLVKP PSALMRPRIA
810 820 830
SRVLGKWART RLSGQKTLIA RNYENHPIPA EPADQLVNA
Length:839
Mass (Da):93,429
Last modified:May 1, 1997 - v1
Checksum:i9D6AF11B5B5EA1B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14682.1.
AL123456 Genomic DNA. Translation: CCP44704.1.
RefSeqiNP_216453.1. NC_000962.3.
WP_003409714.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR14682; AIR14682; LH57_10540.
CCP44704; CCP44704; Rv1937.
GeneIDi885433.
KEGGimtu:Rv1937.
mtv:RVBD_1937.
PATRICi18126142. VBIMycTub22151_2183.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14682.1.
AL123456 Genomic DNA. Translation: CCP44704.1.
RefSeqiNP_216453.1. NC_000962.3.
WP_003409714.1. NZ_KK339370.1.

3D structure databases

SMRiP95277. Positions 5-338, 362-393, 481-553, 671-709.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv1937.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR14682; AIR14682; LH57_10540.
CCP44704; CCP44704; Rv1937.
GeneIDi885433.
KEGGimtu:Rv1937.
mtv:RVBD_1937.
PATRICi18126142. VBIMycTub22151_2183.

Organism-specific databases

TubercuListiRv1937.

Phylogenomic databases

eggNOGiCOG0543. LUCA.
HOGENOMiHOG000049240.
OMAiASGKNTH.
OrthoDBiEOG6MPWTK.
PhylomeDBiP95277.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
3.50.50.60. 2 hits.
InterProiIPR001041. 2Fe-2S_ferredoxin-type.
IPR006058. 2Fe2S_fd_BS.
IPR012675. Beta-grasp_dom.
IPR023753. FAD/NAD-binding_dom.
IPR017927. Fd_Rdtase_FAD-bd.
IPR008333. OxRdtase_FAD-bd_dom.
IPR001433. OxRdtase_FAD/NAD-bd.
IPR001221. Phe_hydroxylase.
IPR017938. Riboflavin_synthase-like_b-brl.
[Graphical view]
PfamiPF00970. FAD_binding_6. 1 hit.
PF00111. Fer2. 1 hit.
PF00175. NAD_binding_1. 1 hit.
[Graphical view]
PRINTSiPR00410. PHEHYDRXLASE.
SUPFAMiSSF51905. SSF51905. 2 hits.
SSF54292. SSF54292. 1 hit.
SSF63380. SSF63380. 1 hit.
PROSITEiPS00197. 2FE2S_FER_1. 1 hit.
PS51085. 2FE2S_FER_2. 1 hit.
PS51384. FAD_FR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported and H37RvImported.
  2. "Phylogenetic analysis of Mycobacterial species using whole genome sequences."
    Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J., Monaco A., King S., Sohrabi A.
    Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27294 / TMC 102 / H37RvImported and H37RvImported.

Entry informationi

Entry nameiP95277_MYCTU
AccessioniPrimary (citable) accession number: P95277
Secondary accession number(s): F2GGS8, I6XCW3, Q7D7R3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: April 13, 2016
This is version 128 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.