P95227 (P95227_MYCTU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) EMBL CAB06682.1
EC=6.2.1.- EMBL CAB06682.1

Submitted name:
Substrate--CoA ligase EMBL AAK44502.1

Gene names

Name:	fadD2 EMBL CAB06682.1
Ordered Locus Names:	MT0283, Rv0270

Organism

Mycobacterium tuberculosis

Taxonomic identifier

1773 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium › Mycobacterium tuberculosis complex

Protein attributes

Sequence length	560 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Ligase EMBL CAB06682.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	plasma membrane Inferred from direct assay. Source: MTBBASE
Molecular function	ligase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	P95227 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: 9946AA92F54636A9	FASTA	560	59,893
	10 20 30 40 50 60 MPNLTDLPGQ AVSKLQKSIG QYVARGTAEL HYLRKIIESG AIGLEPPLNY AALAADIRKW 70 80 90 100 110 120 GEVGMLPSHN ARRAPNRAAV IDEEGTLTFS ELDEAAHAVA NGLLAKGVRA GDGVAILARN 130 140 150 160 170 180 HRWFVIANYG AARVGARIIL LNSEFSGPQI KEVSDREGAK VIIYDDEYTK AVSLAQPPLG 190 200 210 220 230 240 KLRALGVNPD DDKPSGSSDE TLAELIAHSS TAPAPKASRR ASIIILTSGT TGTPKGANRN 250 260 270 280 290 300 TPPTLAPIGG ILSHVPFKAG EVTLLPSPMF HALGYMHAAL AMFLGSTLVL RRRFKPALVL 310 320 330 340 350 360 EDIEKHKATS MVVVPVMLSR ILDQLEKTEP KPDLSSLKIV FVSGSQLGAE LATRALGDLG 370 380 390 400 410 420 PVIYNMYGST EVAFATIAGP KDLQFNPSTV GPVVKGVTVK ILDENGNEVP QGAVGRIFVG 430 440 450 460 470 480 NAFPFEGYTG GGGKQIIDGL LSSGDVGYFD ERGLLYVSGR DDEMIVSGGE NVFPAEVEDL 490 500 510 520 530 540 ISGHPDVVEA AAIGVDDKEF GARLRAFVVK KPGADLDEDT IKQYVRDHLA RYKVPREVIF 550 560 LDELPRNPTG KVLKRELRKL

References

[1]

"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence." Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K. , Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Nature 393:537-544(1998) [PubMed: 9634230] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25618 / H37Rv.

[2]

"Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains." Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J., DeBoy R., Dodson R., Gwinn M., Haft D., Hickey E., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M., Salzberg S.L., Delcher A., Utterback T. , Weidman J., Khouri H., Gill J., Mikula A., Bishai W., Jacobs Jr W.R. Jr, Venter J.C., Fraser C.M. J. Bacteriol. 184:5479-5490(2002) [PubMed: 12218036] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CDC 1551 / Oshkosh.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000516 Genomic DNA. Translation: AAK44502.1. BX842572 Genomic DNA. Translation: CAB06682.1.
PIR	A70628.
RefSeq	NP_214784.1. NC_000962.2. NP_334688.1. NC_002755.2.
3D structure databases
HSSP	HSSP built from PDB template 1LCI based on UniProtKB P08659.
ProteinModelPortal	P95227.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000000328; EBMYCP00000000328; EBMYCG00000000328. EBMYCT00000069391; EBMYCP00000067450; EBMYCG00000069386.
GeneID	886637. 923212.
GenomeReviews	Gene locus MT0283 in contig AE000516_GR. Gene locus Rv0270 in contig AL123456_GR.
KEGG	mtc:MT0283. mtu:Rv0270.
PATRIC	18122339. VBIMycTub22151_0304.
TIGR	MT0283.
Organism-specific databases
TubercuList	Rv0270.
Phylogenomic databases
GeneTree	EBGT00050000015138.
HOGENOM	HBG547964.
OMA	LHATIAM.
PhylomeDB	P95227.
ProtClustDB	PRK07788.
Family and domain databases
InterPro	IPR020845. AMP-binding_CS. IPR000873. AMP-dep_Synth/Lig. [Graphical view]
KO	K00666.
Pfam	PF00501. AMP-binding. 1 hit. [Graphical view]
PROSITE	PS00455. AMP_BINDING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P95227_MYCTU

Accession

Primary (citable) accession number: P95227
Secondary accession number(s): Q7DA47

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1997
Last sequence update:	May 1, 1997
Last modified:	December 14, 2011
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)