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Protein
Submitted name:

Probable membrane NADH dehydrogenase NdhA

Gene

ndhA

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • NAD(P)H dehydrogenase (quinone) activity Source: MTBBASE

GO - Biological processi

  • growth of symbiont in host cell Source: MTBBASE
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Probable membrane NADH dehydrogenase NdhAImported
Gene namesi
Name:ndhAImported
Ordered Locus Names:Rv0392cImported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome

Organism-specific databases

TubercuListiRv0392c.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei389 – 40719HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • cytosol Source: MTBBASE
  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: MTBBASE
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiP95200.

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv0392c.

Structurei

3D structure databases

ProteinModelPortaliP95200.
SMRiP95200. Positions 16-426.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 340326FAD/NAD-binding_domInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105CEP. Bacteria.
COG1252. LUCA.
HOGENOMiHOG000241051.
KOiK03885.
OMAiRYSAVAQ.
OrthoDBiEOG6QZMR6.
PhylomeDBiP95200.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.

Sequencei

Sequence statusi: Complete.

P95200-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLSSGEPSA VGGRHRVVII GSGFGGLNAA KALKRADVDI TLISKTTTHL
60 70 80 90 100
FQPLLYQVAT GILSEGDIAP TTRLILRRQK NVRVLLGEVN AIDLKAQTVT
110 120 130 140 150
SKLMDMTTVT PYDSLIVAAG AQQSYFGNDE FATFAPGMKT IDDALELRGR
160 170 180 190 200
ILGAFEAAEV STDHAERERR LTFVVVGAGP TGVEVAGQIV ELAERTLAGA
210 220 230 240 250
FRTITPSECR VILLDAAPAV LPPMGPKLGL KAQRRLEKMD VEVQLNAMVT
260 270 280 290 300
AVDYKGITIK EKDGGERRIE CACKVWAAGV AASPLGKMIA EGSDGTEIDR
310 320 330 340 350
AGRVIVEPDL TVKGHPNVFV VGDLMFVPGV PGVAQGAIQG ARYATTVIKH
360 370 380 390 400
MVKGNDDPAN RKPFHYFNKG SMATISRHSA VAQVGKLEFA GYFAWLAWLV
410 420 430 440 450
LHLVYLVGYR NRIAALFAWG ISFMGRARGQ MAITSQMIYA RLVMTLMEQQ
460 470
AQGALAAAEQ AEHAEQEAAG
Length:470
Mass (Da):50,385
Last modified:May 1, 1997 - v1
Checksum:i584208FA80048828
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA. Translation: CCP43122.1.
RefSeqiNP_214906.1. NC_000962.3.
WP_003898428.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiCCP43122; CCP43122; Rv0392c.
GeneIDi886430.
KEGGimtu:Rv0392c.
mtv:RVBD_0392c.
PATRICi18122602. VBIMycTub22151_0435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL123456 Genomic DNA. Translation: CCP43122.1.
RefSeqiNP_214906.1. NC_000962.3.
WP_003898428.1. NZ_KK339370.1.

3D structure databases

ProteinModelPortaliP95200.
SMRiP95200. Positions 16-426.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv0392c.

Proteomic databases

PaxDbiP95200.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCP43122; CCP43122; Rv0392c.
GeneIDi886430.
KEGGimtu:Rv0392c.
mtv:RVBD_0392c.
PATRICi18122602. VBIMycTub22151_0435.

Organism-specific databases

TubercuListiRv0392c.

Phylogenomic databases

eggNOGiENOG4105CEP. Bacteria.
COG1252. LUCA.
HOGENOMiHOG000241051.
KOiK03885.
OMAiRYSAVAQ.
OrthoDBiEOG6QZMR6.
PhylomeDBiP95200.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiP95200_MYCTU
AccessioniPrimary (citable) accession number: P95200
Secondary accession number(s): F2GN78, I6WYA2, Q7D9W6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: May 11, 2016
This is version 120 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.