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Protein
Submitted name:

NADH dehydrogenase

Gene

ndh

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • NAD(P)H dehydrogenase (quinone) activity Source: MTBBASE

GO - Biological processi

  • aerobic electron transport chain Source: MTBBASE
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
NADH dehydrogenaseImported
Submitted name:
Probable NADH dehydrogenase NdhImported
Gene namesi
Name:ndhImported
Ordered Locus Names:Rv1854cImported
ORF Names:LH57_10110Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Organism-specific databases

TubercuListiRv1854c.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei387 – 40721HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of plasma membrane Source: MTBBASE
  • plasma membrane Source: MTBBASE
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv1854c.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 339325FAD/NAD-binding_domInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105CEP. Bacteria.
COG1252. LUCA.
HOGENOMiHOG000241051.
KOiK03885.
OMAiHQMASLV.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.

Sequencei

Sequence statusi: Complete.

P95160-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPQQEPTAQ PPRRHRVVII GSGFGGLNAA KKLKRADVDI KLIARTTHHL
60 70 80 90 100
FQPLLYQVAT GIISEGEIAP PTRVVLRKQR NVQVLLGNVT HIDLAGQCVV
110 120 130 140 150
SELLGHTYQT PYDSLIVAAG AGQSYFGNDH FAEFAPGMKS IDDALELRGR
160 170 180 190 200
ILSAFEQAER SSDPERRAKL LTFTVVGAGP TGVEMAGQIA ELAEHTLKGA
210 220 230 240 250
FRHIDSTKAR VILLDAAPAV LPPMGAKLGQ RAAARLQKLG VEIQLGAMVT
260 270 280 290 300
DVDRNGITVK DSDGTVRRIE SACKVWSAGV SASRLGRDLA EQSRVELDRA
310 320 330 340 350
GRVQVLPDLS IPGYPNVFVV GDMAAVEGVP GVAQGAIQGA KYVASTIKAE
360 370 380 390 400
LAGANPAERE PFQYFDKGSM ATVSRFSAVA KIGPVEFSGF IAWLIWLVLH
410 420 430 440 450
LAYLIGFKTK ITTLLSWTVT FLSTRRGQLT ITDQQAFART RLEQLAELAA
460
EAQGSAASAK VAS
Length:463
Mass (Da):49,619
Last modified:May 1, 1997 - v1
Checksum:i97D9D0CFF0B886C5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14602.1.
AL123456 Genomic DNA. Translation: CCP44620.1.
RefSeqiNP_216370.1. NC_000962.3.
WP_003409317.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR14602; AIR14602; LH57_10110.
CCP44620; CCP44620; Rv1854c.
GeneIDi885746.
KEGGimtu:Rv1854c.
mtv:RVBD_1854c.
PATRICi18125945. VBIMycTub22151_2085.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR14602.1.
AL123456 Genomic DNA. Translation: CCP44620.1.
RefSeqiNP_216370.1. NC_000962.3.
WP_003409317.1. NZ_KK339370.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv1854c.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR14602; AIR14602; LH57_10110.
CCP44620; CCP44620; Rv1854c.
GeneIDi885746.
KEGGimtu:Rv1854c.
mtv:RVBD_1854c.
PATRICi18125945. VBIMycTub22151_2085.

Organism-specific databases

TubercuListiRv1854c.

Phylogenomic databases

eggNOGiENOG4105CEP. Bacteria.
COG1252. LUCA.
HOGENOMiHOG000241051.
KOiK03885.
OMAiHQMASLV.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
InterProiIPR023753. FAD/NAD-binding_dom.
[Graphical view]
PfamiPF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiP95160_MYCTU
AccessioniPrimary (citable) accession number: P95160
Secondary accession number(s): F2GI96, I6XZ55, Q7D7W7
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: May 1, 1997
Last modified: September 7, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.