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Protein
Submitted name:

Possible transcriptional regulatory protein (Probably TetR-family)

Gene

Rv3058c

Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciMTBRV:RV3058C-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Possible transcriptional regulatory protein (Probably TetR-family)Imported
Submitted name:
TetR family transcriptional regulatorImported
Gene namesi
Ordered Locus Names:Rv3058cImported
ORF Names:LH57_16695Imported
OrganismiMycobacterium tuberculosis (strain ATCC 25618 / H37Rv)Imported
Taxonomic identifieri83332 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
Proteomesi
  • UP000001584 Componenti: Chromosome
  • UP000031768 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: GO_Central
  • plasma membrane Source: MTBBASE
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi83332.Rv3058c.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 8061HTH tetR-type DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 HTH tetR-type DNA-binding domain.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105IYX. Bacteria.
ENOG41124ZB. LUCA.
HOGENOMiHOG000050494.
OMAiEIMDDFQ.
OrthoDBiEOG63C0SD.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P95100-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSHAADEKQ AAPPMRRRGD RHRQAILRAA RELLEETPFA ELSVRAISLR
60 70 80 90 100
AGVARSGFYF YFDSKYSVLA QILAEATEEL EEASQHFSAR QPGESPEQFV
110 120 130 140 150
NRMIGSVAAV YANNDPVLRA CNAARQSDME IRDILERQFQ VLLRETIGVF
160 170 180 190 200
EAEVKAGTAH PISEDLPTLV RTLAATTALM LTGDALLVGP DSDAARRVRV
210
LEQMWLNALW GGGKAP
Length:216
Mass (Da):23,835
Last modified:July 5, 2004 - v4
Checksum:iBDD332678E39485F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR15839.1.
AL123456 Genomic DNA. Translation: CCP45867.1.
RefSeqiNP_217574.1. NC_000962.3.
WP_003415987.1. NZ_KK339370.1.

Genome annotation databases

EnsemblBacteriaiAIR15839; AIR15839; LH57_16695.
CCP45867; CCP45867; Rv3058c.
GeneIDi888878.
KEGGimtu:Rv3058c.
mtv:RVBD_3058c.
PATRICi18155399. VBIMycTub87468_3412.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP009480 Genomic DNA. Translation: AIR15839.1.
AL123456 Genomic DNA. Translation: CCP45867.1.
RefSeqiNP_217574.1. NC_000962.3.
WP_003415987.1. NZ_KK339370.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi83332.Rv3058c.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIR15839; AIR15839; LH57_16695.
CCP45867; CCP45867; Rv3058c.
GeneIDi888878.
KEGGimtu:Rv3058c.
mtv:RVBD_3058c.
PATRICi18155399. VBIMycTub87468_3412.

Phylogenomic databases

eggNOGiENOG4105IYX. Bacteria.
ENOG41124ZB. LUCA.
HOGENOMiHOG000050494.
OMAiEIMDDFQ.
OrthoDBiEOG63C0SD.

Enzyme and pathway databases

BioCyciMTBRV:RV3058C-MONOMER.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
1.10.357.10. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamiPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSiPR00455. HTHTETR.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEiPS50977. HTH_TETR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25618 / H37RvImported and H37RvImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "Phylogenetic analysis of Mycobacterial species using whole genome sequences."
    Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J., Monaco A., King S., Sohrabi A.
    Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27294 / TMC 102 / H37RvImported and H37RvImported.

Entry informationi

Entry nameiP95100_MYCTU
AccessioniPrimary (citable) accession number: P95100
Secondary accession number(s): I6Y2F2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 1, 1997
Last sequence update: July 5, 2004
Last modified: July 6, 2016
This is version 115 of the entry and version 4 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.