P94888 (P94888_9LACT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cadmium resistance protein EMBL AAB37345.1

Gene names

Name:

cadA EMBL AAB37345.1

Encoded on

Plasmid pND302 EMBL AAB37345.1

Organism

Lactococcus lactis EMBL AAB37345.1

Taxonomic identifier

1358 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Lactococcus

Protein attributes

Sequence length	705 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane RuleBase RU000653
Ligand	ATP-binding RuleBase RU000653 Nucleotide-binding
Molecular function	Hydrolase RuleBase RU000653
PTM	Phosphoprotein RuleBase RU000653
Technical term	Plasmid EMBL AAB37345.1
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cation channel activity Inferred from electronic annotation. Source: InterPro copper-exporting ATPase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	P94888 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: DFF07A0DC41AF325	FASTA	705	76,467
	10 20 30 40 50 60 MSEKMTEKTY RIEGLSCTNC AGKFEKNVKQ LPGVTSATVN FGASKISVEG QTTIEELEEA 70 80 90 100 110 120 GAFENLIIRD DQENDEQVRS KESFIKRNIA LIISLGFILV AVISQLSLGE DHLLTKALYI 130 140 150 160 170 180 LAIIIGGFDL FKEGFSDLIK LDFSMESLMT IAIIGAAFIG EWAEGSIVVI LFAISEALER 190 200 210 220 230 240 FSMDKARQSI RSLMDIAPKE ALIRRNNVEQ LVSVDKIDID DIMIIKPGQK IAMDGLVING 250 260 270 280 290 300 HSSVNQAAIT GESVPVEKQL DDEVFAGTLN EEGILEVKVT KKVTDTTIAK IIHLVEEAQG 310 320 330 340 350 360 ERAPAQAFVD KFAKYYTPFI IIMALLIVVV PPLFFGGDWN KWLYQGLSIL VVGCPCSLVI 370 380 390 400 410 420 STPVSIVSAI GNAAKNGVLV KGGVYLEEIG HLRAIAFDKT GTLTKGKPVV TDFIATSSET 430 440 450 460 470 480 DINYLSIISS LESLSQHPLA SAILNEADKT NVDYKSIQIE DFQSITGKGL TGIHQNIRYY 490 500 510 520 530 540 IGSPKLFSAS VIEETAVKVQ YRQFQEQGKT AMYFGTDEQI LGVIAVADEV RDSSAAVISE 550 560 570 580 590 600 LHKLSIEHTI MLTGDNTKTA ESIGKQLGVT EIKGDLMPQE KLDSIKALRT TYNKVAMVGD 610 620 630 640 650 660 GINDAPALAA STVGIAMGGA GTDTALETAD VALMGDDLQK LPFIVRLSRQ TLKVIKQNIT 670 680 690 700 FSLGIKLLAL LLVIPGWLTL WIAIVADMGA TLLVTLNGLR LMKVK

References

[1]	"Genetic analysis of regions involved in replication and cadmium resistance of the plasmid pND302 from Lactococcus lactis." Liu C.-Q., Khunajakr N., Chia L.G., Deng Y.-M., Charoenchai P., Dunn N.W. Plasmid 38:79-90(1997) [PubMed: 9339465] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: M71 EMBL AAB37345.1.
[2]	Liu C.-Q., Chia G.L., Dunn N.W. Submitted (NOV-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: M71 EMBL AAB37345.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U78967 Genomic DNA. Translation: AAB37345.1.
3D structure databases
HSSP	HSSP built from PDB template 1KQK based on UniProtKB O32220.
ProteinModelPortal	P94888.
SMR	P94888. Positions 5-73.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR006403. ATPase_P-typ_cat/Cu-transptr. IPR001366. ATPase_P-typ_Cd-transp. IPR006404. ATPase_P-typ_Cd/Co/Hg/Pb/Zn. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR006416. ATPase_P-typ_heavy-metal. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR005834. Dehalogen-like_hydro. IPR023214. HAD-like_dom. IPR017969. Heavy-metal-associated_CS. IPR006121. HeavyMe-assoc_HMA. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 1 hit. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 1 hit. G3DSA:3.40.50.1000. HAD-like_dom. 2 hits.
Pfam	PF00122. E1-E2_ATPase. 1 hit. PF00403. HMA. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE. PR00941. CDATPASE.
SUPFAM	SSF56784. HAD-like_dom. 1 hit. SSF55008. HeavyMe_transpt. 1 hit.
TIGRFAMs	TIGR01511. ATPase-IB1_Cu. 1 hit. TIGR01512. ATPase-IB2_Cd. 1 hit. TIGR01525. ATPase-IB_hvy. 1 hit. TIGR01494. ATPase_P-type. 1 hit.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. PS01047. HMA_1. 1 hit. PS50846. HMA_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

P94888_9LACT

Accession

Primary (citable) accession number: P94888

Entry history

Integrated into UniProtKB/TrEMBL:	May 1, 1997
Last sequence update:	May 1, 1997
Last modified:	September 21, 2011
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)