Reviewed, UniProtKB/Swiss-Prot P94694 (DSVB_DESGI)

Names and origin

Protein names

Recommended name:
    Sulfite reductase, dissimilatory-type subunit beta
    EC=1.8.99.3
Alternative name(s):
    Desulfoviridin subunit beta
    Hydrogensulfite reductase subunit beta

Gene names

Name:

dsrB

Organism

Desulfovibrio gigas

Taxonomic identifier

879 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio

Protein attributes

Sequence length	262 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration, a process catalyzed by the sulfate-reducing bacteria.
Catalytic activity	(O3S.S.SO3)2- + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor.
Cofactor	Binds 1 4Fe-4S cluster per subunit By similarity. Binds 2 sirohemes per subunit By similarity.
Subunit structure	Heterohexamer of two alpha, two beta and two gamma subunits By similarity.

Ontologies

Keywords
Ligand	4Fe-4S Iron Iron-sulfur Metal-binding
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW heme binding Inferred from electronic annotation. Source: InterPro hydrogensulfite reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›262	›262	Sulfite reductase, dissimilatory-type subunit beta		PRO_0000080031
Sites
	Metal binding	231	1	Iron-sulfur (4Fe-4S) Potential
	Metal binding	258	1	Iron-sulfur (4Fe-4S) Potential
	Metal binding	261	1	Iron-sulfur (4Fe-4S) Potential
Experimental info
	Non-terminal residue	262	1

Sequences

	Sequence		Length	Mass (Da)
	P94694-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: 2D4DA1C19B7DCE5D	FASTA	262	28,569
	10 20 30 40 50 60 MAFISSGYNP AKPMENRITD IGPRKFTEFF PPVIAKNAGN WDYHEILEPG ILVHVAKNGD 70 80 90 100 110 120 KVFTVRCGAA RLMSTSHIRE ACEIAKKFCN GHLRFTTRNN IEFMVDNEET LKALVADLKT 130 140 150 160 170 180 RKFAAGSFKF PIGGTGASIS NIVHTQGWVY CHTPATDASG PVKAVMDELF EEFTSMRLPA 190 200 210 220 230 240 IVRVSLACCI NMCGAVHCSD IGLVGIHRKP PMIDHENLAN LCEIPLAVAA CPTAAVKPIT 250 260 AEVNGQKVKS VAINNDRCMY CG

References

[1]	Hipp W.M., Trueper H.G. Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 19364 / DSM 1382 / NCIB 9332 / VKM B-1759.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U80961 Genomic DNA. Translation: AAB41002.1.
3D structure databases
SMR	P94694. Positions 15-262.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.8.99.3. 7582.
Family and domain databases
InterPro	IPR005117. NiRdtase/SiRdtase_haem-b_fer. IPR006067. NO2/SO3_Rdtase_4Fe4S_dom. [Graphical view]
Pfam	PF01077. NIR_SIR. 1 hit. PF03460. NIR_SIR_ferr. 1 hit. [Graphical view]
PROSITE	PS00198. 4FE4S_FER_1. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DSVB_DESGI

Accession

Primary (citable) accession number: P94694

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	May 1, 1997
Last modified:	January 19, 2010
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)