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P94616 (SYGA_COXBU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycine--tRNA ligase alpha subunit

EC=6.1.1.14
Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS
Gene names
Name:glyQ
Ordered Locus Names:CBU_1913
OrganismCoxiella burnetii (strain RSA 493 / Nine Mile phase I) [Reference proteome] [HAMAP]
Taxonomic identifier227377 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella

Protein attributes

Sequence length319 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP-Rule MF_00254

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00254.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glycine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 319319Glycine--tRNA ligase alpha subunit HAMAP-Rule MF_00254
PRO_0000072835

Regions

Compositional bias301 – 3055Poly-Ser HAMAP-Rule MF_00254

Sequences

Sequence LengthMass (Da)Tools
P94616 [UniParc].

Last modified May 1, 1997. Version 1.
Checksum: FF52579A9F0787F8

FASTA31936,397
        10         20         30         40         50         60 
MKSSHPVNFQ QMILALQEYW ASQGCVLLQP FDMEVGAGTF HPATFLRAIG PEPWRAAYVQ 

        70         80         90        100        110        120 
PSRRPTDGRY GDNPNRTQHY YQFQVVLKPS PDDIQDIYLG SLKALGIDPL THDIRFVEDN 

       130        140        150        160        170        180 
WEAPTLGSWG VGWEVWQDGM EITQFTYFQQ IGGLECKPVT GEITYGLERL AMFLQGIDNM 

       190        200        210        220        230        240 
FDLVWTEGPN GRVTYGQIFQ QNEVEMSAYN FEYANVEALF NFFDFYEKEA SQLIEVHLPL 

       250        260        270        280        290        300 
AAYEMVLKAS HTFNLLDARQ AISVTERQRF ILRVRKLAQA VAEAYYSARE KLGFPMLEEI 

       310 
SSSSSRVLPL AGNDRVKGC 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Y10435 Genomic DNA. Translation: CAA71456.1.
AE016828 Genomic DNA. Translation: AAO91404.1.
RefSeqNP_820890.1. NC_002971.3.

3D structure databases

ProteinModelPortalP94616.
SMRP94616. Positions 9-285.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227377.CBU_1913.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO91404; AAO91404; CBU_1913.
GeneID1209826.
KEGGcbu:CBU_1913.
PATRIC17932561. VBICoxBur82552_1897.

Phylogenomic databases

eggNOGCOG0752.
HOGENOMHOG000264291.
KOK01878.
OMACVILQPY.
OrthoDBEOG661H9S.
ProtClustDBPRK09348.

Enzyme and pathway databases

BioCycCBUR227377:GJ7S-1887-MONOMER.

Family and domain databases

HAMAPMF_00254. Gly_tRNA_synth_alpha.
InterProIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSPR01044. TRNASYNTHGA.
TIGRFAMsTIGR00388. glyQ. 1 hit.
PROSITEPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYGA_COXBU
AccessionPrimary (citable) accession number: P94616
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: May 1, 1997
Last modified: February 19, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Coxiella burnetii

Coxiella burnetii (strain RSA 493): entries and gene names

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries