Reviewed,
UniProtKB/Swiss-Prot P94616 (SYGA_COXBU)
Last modified
November 3, 2009.
Version 65.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Glycyl-tRNA synthetase alpha subunit EC=6.1.1.14 Alternative name(s): Glycine--tRNA ligase alpha subunit Short name=GlyRS | ||||
| Gene names |
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| Organism | Coxiella burnetii [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 777 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Coxiellaceae › Coxiella |
Protein attributes
| Sequence length | 319 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Catalytic activity | ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254 |
| Subunit structure | Tetramer of two alpha and two beta subunits By similarity. |
| Subcellular location | |
| Sequence similarities | Belongs to the class-II aminoacyl-tRNA synthetase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Protein biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Aminoacyl-tRNA synthetase Ligase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 319 | 319 | Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254 | PRO_0000072835 | |||||
Regions | |||||||||
| Compositional bias | 301 – 305 | 5 | Poly-Ser HAMAP MF_00254 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | Willems H., Jaeger C. Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493. |
| [2] | "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii." Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C., Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M., Lee K.H., Carty H.A. Heidelberg J.F.Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003) [PubMed: 12704232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Nine Mile phase I / RSA 493. |
Cross-references
Sequence databases | |
|---|---|
| Y10435 Genomic DNA. Translation: CAA71456.1. AE016828 Genomic DNA. Translation: AAO91404.1. | |
| RefSeq | NP_820890.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1J5W based on UniProtKB Q9WY59. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1209826. |
| GenomeReviews | Gene locus CBU_1913 in contig AE016828_GR. |
| KEGG | cbu:CBU_1913. |
| NMPDR | fig|227377.1.peg.1834. |
| TIGR | CBU_1913. |
Phylogenomic databases | |
| HOGENOM | P94616. |
| OMA | CRRPTDG. |
Enzyme and pathway databases | |
| BioCyc | CBUR227377:CBU_1913-MON. |
| BRENDA | 6.1.1.14. 256353. |
Family and domain databases | |
| HAMAP | MF_00254. [Tree] |
| InterPro | IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view] |
| Pfam | PF02091. tRNA-synt_2e. 1 hit. [Graphical view] |
| PRINTS | PR01044. TRNASYNTHGA. |
| ProDom | PD006985. tRNA_synt_2e. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR00388. glyQ. 1 hit. |
| PROSITE | PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | SYGA_COXBU | ||||||||
| Accession | Primary (citable) accession number: P94616 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Aminoacyl-tRNA synthetases List of aminoacyl-tRNA synthetase entries |
| Coxiella burnetii Coxiella burnetii (strain RSA 493): entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


