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Protein

tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG

Gene

mnmG

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm5s2U34.UniRule annotation

Cofactori

FADUniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi14 – 19FADUniRule annotation6
Nucleotide bindingi274 – 288NADUniRule annotationAdd BLAST15

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processtRNA processing
LigandFAD, Flavoprotein, NAD

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGUniRule annotation
Alternative name(s):
Glucose-inhibited division protein AUniRule annotation
Gene namesi
Name:mnmGUniRule annotation
Synonyms:gidAUniRule annotation
Ordered Locus Names:CBU_1924
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
Proteomesi
  • UP000002671 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001170911 – 627tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmGAdd BLAST627

Interactioni

Subunit structurei

Homodimer. Heterotetramer of two MnmE and two MnmG subunits.UniRule annotation

Protein-protein interaction databases

STRINGi227377.CBU_1924.

Structurei

3D structure databases

ProteinModelPortaliP94613.
SMRiP94613.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MnmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107RE5. Bacteria.
COG0445. LUCA.
HOGENOMiHOG000201059.
KOiK03495.
OMAiFRPGYAI.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00129. MnmG_GidA. 1 hit.
InterProiView protein in InterPro
IPR036188. FAD/NAD-bd_sf.
IPR026904. GidA-assoc_3.
IPR004416. MnmG.
IPR002218. MnmG-rel.
IPR020595. MnmG-rel_CS.
PANTHERiPTHR11806. PTHR11806. 1 hit.
PTHR11806:SF0. PTHR11806:SF0. 1 hit.
PfamiView protein in Pfam
PF01134. GIDA. 1 hit.
PF13932. GIDA_assoc. 1 hit.
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR00136. gidA. 1 hit.
PROSITEiView protein in PROSITE
PS01280. GIDA_1. 1 hit.
PS01281. GIDA_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P94613-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSTSQQFDV IVVGGGHAGT EAALVAARMG ARTLLLTHNI ETLGQMSCNP
60 70 80 90 100
AIGGIGKSHL VKEIDALGGI MALAADQAGI HFRTLNARKG PAVRATRAQA
110 120 130 140 150
DRVLYKAAIH HALENQPHLW LFQQGVDDLI IQNNRAAGVV TQMGLAFYAP
160 170 180 190 200
TVILTVGTFL GGKIHIGMNH YRGGRAGDPP ALALAERLRE MPFRVERLKT
210 220 230 240 250
GTPPRIDGRT INYSQLIEQP SDQPLPLMSY WSHGEDRPRQ VSCFITQTNE
260 270 280 290 300
KTHDIIRNGL KTSPLFSGVI EGVGPRYCPS IEDKIVRFAD RNSHQLFLEP
310 320 330 340 350
EGLNTPEVYP NGVSTSLSFD VQLDFIHSIK GLEKCHITRP GYAIEYDYFD
360 370 380 390 400
PRDLKPSLET KYVPGLYFAG QINGTTGYEE AAAQGLIAGI NAALQIQERA
410 420 430 440 450
PWTPARDEAY IGVLIDDLTT RGTNEPYRMF TSRAEYRLLL RQDNADLRLT
460 470 480 490 500
EKGRDLGCVD DERWNFFVKK KETIEKEQQR LKKQRIWPKS TVAKAIESRF
510 520 530 540 550
QQLLERDYSA MDLLRRPEIN YPALMQIEEL GPAVLEPSVA EQIDIQAKYE
560 570 580 590 600
GYLTHQLAEI ARQKKYQTAQ IPSSLDYNQV TGLSNEVRQK LNETKPTTLG
610 620
QASRIPGITP AAISLLLVHL KKKELYP
Length:627
Mass (Da):69,969
Last modified:May 9, 2003 - v2
Checksum:i6354640D5DB4837E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti12V → A in CAA71459 (Ref. 1) Curated1
Sequence conflicti214S → Y in CAA71459 (Ref. 1) Curated1
Sequence conflicti237R → H in CAA71459 (Ref. 1) Curated1
Sequence conflicti295Q → R in CAA71459 (Ref. 1) Curated1
Sequence conflicti303L → I in CAA71459 (Ref. 1) Curated1
Sequence conflicti313V → L in CAA71459 (Ref. 1) Curated1
Sequence conflicti325F → V in CAA71459 (Ref. 1) Curated1
Sequence conflicti329 – 330IK → KT in CAA71459 (Ref. 1) Curated2
Sequence conflicti333E → A in CAA71459 (Ref. 1) Curated1
Sequence conflicti343A → T in CAA71459 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10436 Genomic DNA. Translation: CAA71459.1.
AE016828 Genomic DNA. Translation: AAO91415.2.
RefSeqiNP_820901.2. NC_002971.3.
WP_010958541.1. NZ_CCYB01000002.1.

Genome annotation databases

EnsemblBacteriaiAAO91415; AAO91415; CBU_1924.
GeneIDi1209837.
31482839.
KEGGicbu:CBU_1924.
PATRICifig|227377.7.peg.1906.

Similar proteinsi

Entry informationi

Entry nameiMNMG_COXBU
AccessioniPrimary (citable) accession number: P94613
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 9, 2003
Last modified: October 25, 2017
This is version 108 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families