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P94556 (MURI1_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate racemase 1
EC=5.1.1.3
Gene names
Name:racE
Synonyms:glr, murI
Ordered Locus Names:BSU28390
OrganismBacillus subtilis
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length272 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258

Catalytic activity

L-glutamate = D-glutamate. HAMAP MF_00258

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258

Sequence similarities

Belongs to the aspartate/glutamate racemases family.

Sequence caution

The sequence BAA28871.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 272272Glutamate racemase 1 HAMAP MF_00258
PRO_0000095453

Experimental info

Sequence conflict1601K → Q in CAA99552. Ref.2

Secondary structure

1 .............................................. 272
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P94556 [UniParc].

Last modified July 7, 2009. Version 2.
Checksum: 97489B93A48471FA

FASTA27229,998
        10         20         30         40         50         60 
MLEQPIGVID SGVGGLTVAK EIMRQLPKEN IIYVGDTKRC PYGPRPEEEV LQYTWELTNY 

        70         80         90        100        110        120 
LLENHHIKML VIACNTATAI ALDDIQRSVG IPVVGVIQPG ARAAIKVTDN QHIGVIGTEN 

       130        140        150        160        170        180 
TIKSNAYEEA LLALNPDLKV ENLACPLLVP FVESGKFLDK TADEIVKTSL YPLKDTSIDS 

       190        200        210        220        230        240 
LILGCTHYPI LKEAIQRYMG EHVNIISSGD ETAREVSTIL SYKGLLNQSP IAPDHQFLTT 

       250        260        270 
GARDQFAKIA DDWFGHEVGH VECISLQEPI KR

« Hide

References

« Hide 'large scale' references
[1]"An internal FK506-binding domain is the catalytic core of the prolyl isomerase activity associated with the Bacillus subtilis trigger factor."
Goethel S.F., Schmid R., Wipat A., Carter N.M., Emmerson P.T., Harwood C.R., Marahiel M.A.
Eur. J. Biochem. 244:59-65(1997) [PubMed: 9063446] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The dnaB-pheA (256 degrees-240 degrees) region of the Bacillus subtilis chromosome containing genes responsible for stress responses, the utilization of plant cell walls and primary metabolism."
Wipat A., Carter N., Brignell C.S., Guy J.B., Piper K., Sanders J., Emmerson P.T., Harwood C.R.
Microbiology 142:3067-3078(1996) [PubMed: 8969504] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed: 9384377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.
[4]"From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later."
Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.
Microbiology 155:1758-1775(2009) [PubMed: 19383706] [Abstract]
Cited for: SEQUENCE REVISION TO 160.
[5]"Properties of glutamate racemase from Bacillus subtilis IFO 3336 producing poly-gamma-glutamate."
Ashiuchi M., Tani K., Soda K., Misono H.
J. Biochem. 123:1156-1163(1998) [PubMed: 9604005] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 2-272.
Strain: NBRC 3336.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		Z75208 Genomic DNA. Translation: CAA99552.1.
AL009126 Genomic DNA. Translation: CAB14799.2.
AB003685 Genomic DNA. Translation: BAA28871.1. Different initiation.
PIRB69688.
RefSeqNP_390717.2. NC_000964.3.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1ZUWX-ray1.75A/B/C1-272[»]
ProteinModelPortalP94556.
SMRP94556. Positions 2-268.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000002033; EBBACP00000002033; EBBACG00000002030.
GeneID935934.
GenomeReviewsGene locus BSU28390 in contig AL009126_GR.
KEGGbsu:BSU28390.
PATRIC18977562. VBIBacSub10457_2969.

Organism-specific databases

GenoListBSU28390. [Micado]

Phylogenomic databases

GeneTreeEBGT00050000002346.
HOGENOMHBG645102.
PhylomeDBP94556.
ProtClustDBPRK00865.

Enzyme and pathway databases

BioCycBSUB:BSU28390-MONOMER.

Family and domain databases

HAMAPMF_00258. Glu_racemase.
[Tree]
InterProIPR015942. Asp/Glu/hydantoin_racemase.
IPR001920. Asp/Glu_race.
IPR018187. Asp/Glu_racemase_AS.
IPR004391. Glu_race.
[Graphical view]
Gene3DG3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KOK01776.
PANTHERPTHR21198. PTHR21198. 1 hit.
PfamPF01177. Asp_Glu_race. 1 hit.
[Graphical view]
SUPFAMSSF53681. Asp/Glu_race. 2 hits.
TIGRFAMsTIGR00067. Glut_race. 1 hit.
PROSITEPS00923. ASP_GLU_RACEMASE_1. 1 hit.
PS00924. ASP_GLU_RACEMASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameMURI1_BACSU
AccessionPrimary (citable) accession number: P94556
Secondary accession number(s): O82826
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: July 7, 2009
Last modified: January 25, 2012
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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