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P94526 (ARAL_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Arabinose operon protein AraL
Gene names
Name:araL
Synonyms:yseA
Ordered Locus Names:BSU28770
OrganismBacillus subtilis
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length272 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Induction

Transcription is repressed by glucose and by the binding of AraR to the operon promoter. L-arabinose acts as an inducer by inhibiting the binding of AraR to the DNA, thus allowing expression of the gene. Ref.4

Sequence caution

The sequence CAA61588.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular functionhydrolase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 272272Arabinose operon protein AraL
PRO_0000064658

Sequences

Sequence LengthMass (Da)Tools
P94526 [UniParc].

Last modified May 1, 1997. Version 1.
Checksum: E035F890C004C51A

FASTA27229,315
        10         20         30         40         50         60 
MRIMASHDTP VSPAGILIDL DGTVFRGNEL IEGAREAIKT LRRMGKKIVF LSNRGNISRA 

        70         80         90        100        110        120 
MCRKKLLGAG IETDVNDIVL SSSVTAAFLK KHYRFSKVWV LGEQGLVDEL RLAGVQNASE 

       130        140        150        160        170        180 
PKEADWLVIS LHETLTYDDL NQAFQAAAGG ARIIATNKDR SFPNEDGNAI DVAGMIGAIE 

       190        200        210        220        230        240 
TSAQAKTELV VGKPSWLMAE AACTAMGLSA HECMIIGDSI ESDIAMGKLY GMKSALVLTG 

       250        260        270 
SAKQGEQRLY TPDYVLDSIK DVTKLAEEGI LI

« Hide

References

« Hide 'large scale' references
[1]"The Bacillus subtilis L-arabinose (ara) operon: nucleotide sequence, genetic organization and expression."
Sa-Nogueira I.M.G., Nogueira T.V., Soares S., de Lencastre H.
Microbiology 143:957-969(1997) [PubMed: 9084180] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[2]"The dnaB-pheA (256 degrees-240 degrees) region of the Bacillus subtilis chromosome containing genes responsible for stress responses, the utilization of plant cell walls and primary metabolism."
Wipat A., Carter N., Brignell C.S., Guy J.B., Piper K., Sanders J., Emmerson P.T., Harwood C.R.
Microbiology 142:3067-3078(1996) [PubMed: 8969504] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168.
[3]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed: 9384377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.
[4]"Mode of action of AraR, the key regulator of L-arabinose metabolism in Bacillus subtilis."
Mota L.J., Tavares P., Sa-Nogueira I.M.G.
Mol. Microbiol. 33:476-489(1999) [PubMed: 10417639] [Abstract]
Cited for: TRANSCRIPTIONAL REGULATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X89408 Genomic DNA. Translation: CAA61588.1. Different initiation.
X89810 Genomic DNA. Translation: CAA61932.1.
Z75208 Genomic DNA. Translation: CAA99590.1.
AL009126 Genomic DNA. Translation: CAB14837.1.
PIRG69587.
RefSeqNP_390755.1. NC_000964.3.

3D structure databases

ProteinModelPortalP94526.
SMRP94526. Positions 12-266.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000003624; EBBACP00000003624; EBBACG00000003617.
GeneID937431.
GenomeReviewsGene locus BSU28770 in contig AL009126_GR.
KEGGbsu:BSU28770.
NMPDRfig|224308.1.peg.2880.
PATRIC18977646. VBIBacSub10457_3011.

Organism-specific databases

GenoListBSU28770. [Micado]

Phylogenomic databases

GeneTreeEBGT00050000000481.
HOGENOMHBG646794.
OMAIPHADEA.
PhylomeDBP94526.
ProtClustDBCLSK887697.

Enzyme and pathway databases

BioCycBSUB:BSU28770-MONOMER.

Family and domain databases

InterProIPR005834. Dehalogen-like_hydro.
IPR023214. HAD-like_dom.
IPR006357. HAD-SF_hydro_IIA.
IPR023215. NPhePase-like_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.1000. HAD-like_dom. 2 hits.
G3DSA:3.40.50.10410. NPhePase-like_dom. 1 hit.
KOK02101.
PfamPF00702. Hydrolase. 1 hit.
[Graphical view]
SUPFAMSSF56784. HAD-like_dom. 1 hit.
TIGRFAMsTIGR01460. HAD-SF-IIA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameARAL_BACSU
AccessionPrimary (citable) accession number: P94526
Entry history
Integrated into UniProtKB/Swiss-Prot: August 2, 2002
Last sequence update: May 1, 1997
Last modified: January 25, 2012
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents