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Protein

Sensor histidine kinase YfiJ

Gene

yfiJ

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Member of the two-component regulatory system YfiJ/YfiK. Probably activates YfiK by phosphorylation.1 Publication

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Two-component regulatory system

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSUB:BSU08290-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Sensor histidine kinase YfiJ (EC:2.7.13.3)
Gene namesi
Name:yfiJ
Ordered Locus Names:BSU08290
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 22ExtracellularSequence analysis
Transmembranei3 – 2321HelicalSequence analysisAdd
BLAST
Topological domaini24 – 274CytoplasmicSequence analysis
Transmembranei28 – 4821HelicalSequence analysisAdd
BLAST
Topological domaini49 – 6113ExtracellularSequence analysisAdd
BLAST
Transmembranei62 – 8221HelicalSequence analysisAdd
BLAST
Topological domaini83 – 10119CytoplasmicSequence analysisAdd
BLAST
Transmembranei102 – 12221HelicalSequence analysisAdd
BLAST
Topological domaini123 – 1253ExtracellularSequence analysis
Transmembranei126 – 14621HelicalSequence analysisAdd
BLAST
Topological domaini147 – 400254CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Sensor histidine kinase YfiJPRO_0000360783Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei201 – 2011Phosphohistidine; by autocatalysisBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP94438.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100004603.

Structurei

3D structure databases

ProteinModelPortaliP94438.
SMRiP94438. Positions 300-385.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini190 – 385196Histidine kinaseAdd
BLAST

Sequence similaritiesi

Contains 1 histidine kinase domain.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
HOGENOMiHOG000002035.
InParanoidiP94438.
OMAiLATFSHI.
PhylomeDBiP94438.

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR011712. Sig_transdc_His_kin_sub3_dim/P.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF07730. HisKA_3. 1 hit.
[Graphical view]
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF55874. SSF55874. 1 hit.

Sequencei

Sequence statusi: Complete.

P94438-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKALFFTRMF TLMVSCLMYL SIVKEDNWFG YVFIAAGAAM YAANHVLLTK
60 70 80 90 100
ETNAIWFCLI DIAIGFSFGF IFPGTGLFII MLCPVAVAFF LRGFPKRTAW
110 120 130 140 150
SVLCLSSILF LTVLIRTYAM FGNEFVIDHL TSMTFVVFCG VVGKLIRKLL
160 170 180 190 200
DAQDTAKQQF QELTESHLAL SAAHQELHLY AKQVEELTAI YERNRMAREI
210 220 230 240 250
HDTVGHKMTA LLVQLQLLRE WQKRDSQKAD ETVGVCETLA REALDDVRLS
260 270 280 290 300
VRTLQTENDP SLIESLKQLT EDFCKNAGVT TEFAVSGDPA IIPLSLHPTL
310 320 330 340 350
IRTVQEALTN AKRHGGAAAC SIQLACTTDS ISLVIKDDGK GNPEAALGFG
360 370 380 390 400
LLNMKKRAAE HGGMIRFESE RDQGFTVNAE FSLANKKWSF GPVQQKESLS
Length:400
Mass (Da):44,543
Last modified:May 1, 1997 - v1
Checksum:i9FA89B7D8149BEAD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D78508 Genomic DNA. Translation: BAA11400.1.
AL009126 Genomic DNA. Translation: CAB12658.1.
PIRiJC5358.
RefSeqiNP_388710.1. NC_000964.3.
WP_009966811.1. NC_000964.3.

Genome annotation databases

EnsemblBacteriaiCAB12658; CAB12658; BSU08290.
GeneIDi936171.
KEGGibsu:BSU08290.
PATRICi18973310. VBIBacSub10457_0869.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D78508 Genomic DNA. Translation: BAA11400.1.
AL009126 Genomic DNA. Translation: CAB12658.1.
PIRiJC5358.
RefSeqiNP_388710.1. NC_000964.3.
WP_009966811.1. NC_000964.3.

3D structure databases

ProteinModelPortaliP94438.
SMRiP94438. Positions 300-385.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100004603.

Proteomic databases

PaxDbiP94438.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12658; CAB12658; BSU08290.
GeneIDi936171.
KEGGibsu:BSU08290.
PATRICi18973310. VBIBacSub10457_0869.

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
HOGENOMiHOG000002035.
InParanoidiP94438.
OMAiLATFSHI.
PhylomeDBiP94438.

Enzyme and pathway databases

BioCyciBSUB:BSU08290-MONOMER.

Family and domain databases

Gene3Di3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR011712. Sig_transdc_His_kin_sub3_dim/P.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF07730. HisKA_3. 1 hit.
[Graphical view]
SMARTiSM00387. HATPase_c. 1 hit.
[Graphical view]
SUPFAMiSSF55874. SSF55874. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYFIJ_BACSU
AccessioniPrimary (citable) accession number: P94438
Secondary accession number(s): Q796Z9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: May 1, 1997
Last modified: September 7, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.