P94417 (AK3_BACSU) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 84.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Probable aspartokinase EC=2.7.2.4 Alternative name(s): Aspartate kinase | ||||
| Gene names |
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| Organism | Bacillus subtilis | ||||
| Taxonomic identifier | 1423 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus |
Protein attributes
| Sequence length | 454 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | ATP + L-aspartate = ADP + 4-phospho-L-aspartate. |
| Pathway | Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5. |
| Sequence similarities | Belongs to the aspartokinase family. Contains 2 ACT domains. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Diaminopimelate biosynthesis Lysine biosynthesis |
| Domain | Repeat |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | diaminopimelate biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW amino acid bindingInferred from electronic annotation. Source: InterPro aspartate kinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The 25 degrees-36 degrees region of the Bacillus subtilis chromosome: determination of the sequence of a 146 kb segment and identification of 113 genes." Yamane K., Kumano M., Kurita K. Microbiology 142:3047-3056(1996) [PubMed: 8969502] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168. |
| [2] | "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. Danchin A.Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | D50453 Genomic DNA. Translation: BAA09011.1. AL009126 Genomic DNA. Translation: CAB12187.1. |
| PIR | A69763. |
| RefSeq | NP_388261.1. NC_000964.3. |
3D structure databases | |
| ProteinModelPortal | P94417. |
| SMR | P94417. Positions 2-450. |
| ModBase | Search... |
Protein-protein interaction databases | |
| IntAct | P94417. 1 interaction. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBBACT00000000135; EBBACP00000000135; EBBACG00000000135. |
| GeneID | 938276. |
| GenomeReviews | Gene locus BSU03790 in contig AL009126_GR. |
| KEGG | bsu:BSU03790. |
| NMPDR | fig|224308.1.peg.380. |
| PATRIC | 18972332. VBIBacSub10457_0394. |
Organism-specific databases | |
| GenoList | BSU03790. |
Phylogenomic databases | |
| GeneTree | EBGT00050000001782. |
| HOGENOM | HBG724395. |
| OMA | EIGFGRR. |
| PhylomeDB | P94417. |
| ProtClustDB | PRK09034. |
Enzyme and pathway databases | |
| BioCyc | BSUB:BSU03790-MONOMER. MetaCyc:MONOMER-6563. |
Family and domain databases | |
| InterPro | IPR002912. ACT-bd. IPR001048. Asp/Glu/Uridylate_kinase. IPR005260. Asp_kin_monofn. IPR001341. Asp_kinase_dom. IPR018042. Aspartate_kinase_CS. [Graphical view] |
| Gene3D | G3DSA:3.40.1160.10. Aa_kinase. 2 hits. |
| KO | K00928. |
| Pfam | PF00696. AA_kinase. 1 hit. PF01842. ACT. 1 hit. [Graphical view] |
| PIRSF | PIRSF000726. Asp_kin. 1 hit. |
| SUPFAM | SSF53633. Aa_kinase. 1 hit. |
| TIGRFAMs | TIGR00657. Asp_kinases. 1 hit. |
| PROSITE | PS00324. ASPARTOKINASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | AK3_BACSU | ||||||||
| Accession | Primary (citable) accession number: P94417 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Bacillus subtilis Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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