P94340 (RRF_BRUME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosome-recycling factor
Short name=RRF

Alternative name(s):
CP24
Ribosome-releasing factor

Gene names

Name:	frr
Synonyms:	cp24
Ordered Locus Names:	BMEI0826

Organism

Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) [Complete proteome] [HAMAP]

Taxonomic identifier

224914 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella › Brucella melitensis › Brucella melitensis bv. 1

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another By similarity. HAMAP-Rule MF_00040
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the RRF family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translational termination Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	Ribosome-recycling factor HAMAP-Rule MF_00040		PRO_0000167426

Sequences

	Sequence		Length	Mass (Da)
	P94340 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: 5CF102288A21B3A1	FASTA	186	20,723
	10 20 30 40 50 60 MSDAFDINDL KRRMEGAVNA LKHDLGGLRT GRASASLLEP ITIEAYGSTM PINQVANISV 70 80 90 100 110 120 PESRMLSVSV WDKSMVGAVE RAIRDSGLGL NPITDGMTLR IRLPELNEQR RKELVKIAHQ 130 140 150 160 170 180 YAEQGRIAAR HVRRDGMDQL KKLEKDSVIS QDESRVLSEK VQKLTDDTIA EMDKIVAVKE GEIMQV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning, nucleotide sequence, and expression of the gene coding for a ribosome releasing factor-homologous protein of Brucella melitensis." Vizcaino N., Cloeckaert A., Dubray G., Zygmunt M.S. Infect. Immun. 64:4834-4837(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.
[2]	"The genome sequence of the facultative intracellular pathogen Brucella melitensis." DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T., Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G., Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E., Selkov E. , Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J., Haselkorn R., Kyrpides N.C., Overbeek R. Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 16M / ATCC 23456 / NCTC 10094.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U53133 Genomic DNA. Translation: AAB19043.1. AE008917 Genomic DNA. Translation: AAL52007.1.
PIR	AD3355.
RefSeq	NP_539743.1. NC_003317.1.
3D structure databases
ProteinModelPortal	P94340.
ModBase	Search...
Protein-protein interaction databases
STRING	224914.BMEI0826.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAL52007; AAL52007; BMEI0826.
GeneID	1196537.
KEGG	bme:BMEI0826.
PATRIC	17801826. VBIBruMel146950_3233.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000040143.
KO	K02838.
OMA	VMVEYYG.
ProtClustDB	PRK00083.
Family and domain databases
HAMAP	MF_00040. RRF.
InterPro	IPR002661. Ribosome_recyc_fac. IPR023584. Ribosome_recyc_fac_dom. [Graphical view]
PANTHER	PTHR20982. PTHR20982. 1 hit.
Pfam	PF01765. RRF. 1 hit. [Graphical view]
SUPFAM	SSF55194. Ribosome_recyc_fac. 1 hit.
TIGRFAMs	TIGR00496. frr. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RRF_BRUME

Accession

Primary (citable) accession number: P94340

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	May 1, 1997
Last modified:	May 1, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program