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P94325

- CISY_BRADU

UniProt

P94325 - CISY_BRADU

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Protein

Citrate synthase

Gene
gltA, blr4839
Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Acetyl-CoA + H2O + oxaloacetate = citrate + CoA.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei310 – 3101 By similarity
Active sitei368 – 3681 By similarity

GO - Molecular functioni

  1. citrate (Si)-synthase activity Source: InterPro

GO - Biological processi

  1. cellular carbohydrate metabolic process Source: InterPro
  2. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Tricarboxylic acid cycle

Enzyme and pathway databases

BioCyciBJAP224911:GJEJ-4872-MONOMER.
UniPathwayiUPA00223; UER00717.

Names & Taxonomyi

Protein namesi
Recommended name:
Citrate synthase (EC:2.3.3.16)
Gene namesi
Name:gltA
Ordered Locus Names:blr4839
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
ProteomesiUP000002526: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 434434Citrate synthasePRO_0000169939Add
BLAST

Proteomic databases

PRIDEiP94325.

Interactioni

Protein-protein interaction databases

STRINGi224911.blr4839.

Structurei

3D structure databases

ProteinModelPortaliP94325.
SMRiP94325. Positions 9-433.

Family & Domainsi

Sequence similaritiesi

Belongs to the citrate synthase family.

Phylogenomic databases

eggNOGiCOG0372.
HOGENOMiHOG000021224.
KOiK01647.
OrthoDBiEOG6P8TP4.
PhylomeDBiP94325.

Family and domain databases

Gene3Di1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProiIPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-I.
[Graphical view]
PANTHERiPTHR11739. PTHR11739. 1 hit.
PfamiPF00285. Citrate_synt. 1 hit.
[Graphical view]
PIRSFiPIRSF001369. Citrate_synth. 1 hit.
PRINTSiPR00143. CITRTSNTHASE.
SUPFAMiSSF48256. SSF48256. 1 hit.
TIGRFAMsiTIGR01798. cit_synth_I. 1 hit.
PROSITEiPS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P94325-1 [UniParc]FASTAAdd to Basket

« Hide

MDAKASNKTA TLTVGNKNYD LPIHSGSVGP DVIDIGKLYG QSGLFTYDPG    50
FTSTASCQSK ITYIDGDAGV LEYRGYPIEQ LAENGDFLET CYLLLYGNLP 100
TAAQKKDFDD RVIHHTMVHE QMARFFQGFR RDAHPMAVMV ASVGALAAFY 150
HDSTDINDPK QRMIASMRMI AKIPTLAAMA YKYTIGQPFV YPKNSLKFAE 200
NFLHMCFAVP CEEYKINPVL ADALDKIFIL HADHEQNAST STVRIAGSSG 250
ANPFACIAAG IACLWGPAHG GANEAALAML AEIGSVDKIP EFIAKVKDKN 300
SEVRLMGFGH RVYKNYDPRA KIMQKMCHAV LKETGHGDDP MLKVAMELEK 350
IALSDQYFID RKLYPNVDFY SGITLKAMGF PVSMFTVLFA VARTVGWISQ 400
WSEMIEDPQQ KIGRPRQLYT GVTRRDYVAI KDRK 434
Length:434
Mass (Da):48,193
Last modified:February 28, 2003 - v2
Checksum:iDEB33EC2B4BACDB4
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti210 – 2101P → S in AAB39736. 1 Publication
Sequence conflicti281 – 2811A → G in AAB39736. 1 Publication
Sequence conflicti346 – 3461M → L in AAB39736. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U76375 Genomic DNA. Translation: AAB39736.1.
BA000040 Genomic DNA. Translation: BAC50104.1.
RefSeqiNP_771479.1. NC_004463.1.

Genome annotation databases

EnsemblBacteriaiBAC50104; BAC50104; BAC50104.
GeneIDi1052140.
KEGGibja:blr4839.
PATRICi21193340. VBIBraJap65052_4919.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U76375 Genomic DNA. Translation: AAB39736.1 .
BA000040 Genomic DNA. Translation: BAC50104.1 .
RefSeqi NP_771479.1. NC_004463.1.

3D structure databases

ProteinModelPortali P94325.
SMRi P94325. Positions 9-433.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224911.blr4839.

Proteomic databases

PRIDEi P94325.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAC50104 ; BAC50104 ; BAC50104 .
GeneIDi 1052140.
KEGGi bja:blr4839.
PATRICi 21193340. VBIBraJap65052_4919.

Phylogenomic databases

eggNOGi COG0372.
HOGENOMi HOG000021224.
KOi K01647.
OrthoDBi EOG6P8TP4.
PhylomeDBi P94325.

Enzyme and pathway databases

UniPathwayi UPA00223 ; UER00717 .
BioCyci BJAP224911:GJEJ-4872-MONOMER.

Family and domain databases

Gene3Di 1.10.230.10. 1 hit.
1.10.580.10. 1 hit.
InterProi IPR016142. Citrate_synth-like_lrg_a-sub.
IPR016143. Citrate_synth-like_sm_a-sub.
IPR002020. Citrate_synthase-like.
IPR016141. Citrate_synthase-like_core.
IPR019810. Citrate_synthase_AS.
IPR024176. Citrate_synthase_bac-typ.
IPR010953. Citrate_synthase_typ-I.
[Graphical view ]
PANTHERi PTHR11739. PTHR11739. 1 hit.
Pfami PF00285. Citrate_synt. 1 hit.
[Graphical view ]
PIRSFi PIRSF001369. Citrate_synth. 1 hit.
PRINTSi PR00143. CITRTSNTHASE.
SUPFAMi SSF48256. SSF48256. 1 hit.
TIGRFAMsi TIGR01798. cit_synth_I. 1 hit.
PROSITEi PS00480. CITRATE_SYNTHASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning of the Bradyrhizobium japonicum gltA gene encoding a central enzyme of the TCA cycle."
    Levier K., Guerinot M.L.
    Submitted (OCT-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 61A152.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110.

Entry informationi

Entry nameiCISY_BRADU
AccessioniPrimary (citable) accession number: P94325
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 28, 2003
Last modified: September 3, 2014
This is version 85 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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