Uncharacterized protein BB_0381 - Borrelia burgdorferi (Lyme disease spirochete)

Preferred order of sections

Names and origin

Protein names

Recommended name:
Uncharacterized protein BB_0381

Gene names

Ordered Locus Names:

BB_0381

Organism

Borrelia burgdorferi (Lyme disease spirochete)

Taxonomic identifier

139 [NCBI]

Taxonomic lineage

Bacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length	474 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Subcellular location

Membrane; Single-pass membrane protein Potential.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	trehalose metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	alpha,alpha-trehalase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 474

474

Uncharacterized protein BB_0381

PRO_0000174399

Regions

Transmembrane

374 – 398

25

Helical; Potential

Experimental info

Sequence conflict

33

1

L → F in AAC44714. Ref.1

Sequence conflict

40

1

G → T in AAC44714. Ref.1

Sequence conflict

107

1

E → D in AAC44714. Ref.1

Sequence conflict

365

1

S → A in AAC44714. Ref.1

Sequences

Sequence

Length

Mass (Da)

Tools

P94250 [UniParc].

Last modified December 15, 1998. Version 2.
Checksum: 95C37254EDB84929
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FASTA

474

55,673

        10         20         30         40         50         60 
MNKKMFPKIY YYDQDFIDIY NKSLSWIQDK VILQKVADRG KKDKNYYSEN CDYIDQMQAC 

        70         80         90        100        110        120 
MSSFFLVYSN GEYSSTSAID KFYQLQEESG AIRARYDNNN AIIDLDENEE NIGFPIFAWA 

       130        140        150        160        170        180 
EYNLYHKTGN KKRISEVLPI LDKYYKWIES KFLKENGLYS IDVNKIFYKN SPRVDAYYPI 

       190        200        210        220        230        240 
DFNSLQVHNA YCISKLADIL NDKNLSLEYK KRFFSLKVKI NSLMWSEKDG FYYDLDVNEN 

       250        260        270        280        290        300 
ILEIKTIVGF FPMLSEIPSE DRIERMIFYL KSTNHFGTPN PFPTLSVSEP GFSEDGNGYY 

       310        320        330        340        350        360 
GSVYTYMNFF VIKGLEYCGR ANIAREFTIR HLYYILDTLM PFNKIKGHIW EAYRPMQEGP 

       370        380        390        400        410        420 
AYFDSNKKTY TEKGLICYLA LFSISLMIEN IIGLTISLPD KTVYWNIPTL EIMGIESLSL 

       430        440        450        460        470 
KKNQTTIICN KGKRGWEIKM ESEKLYYFTI NILNKKEKTL PIPSGRCSML LDKL

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References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification and mapping of a chromosomal gene cluster of Borrelia burgdorferi containing genes expressed in vivo." Aron L., Toth C., Godfrey H.P., Cabello F.C. FEMS Microbiol. Lett. 145:309-314(1996) [PubMed: 8978084] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 53899 / 297.
[2]	"Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi." Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A., Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L., Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J. Venter J.C. Nature 390:580-586(1997) [PubMed: 9403685] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35210 / B31 / CIP 102532 / DSM 4680.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U49938 Genomic DNA. Translation: AAC44714.1. AE000783 Genomic DNA. Translation: AAC66759.1. Different termination.
PIR	D70147.
RefSeq	NP_212515.1. NC_001318.1.
3D structure databases
ProteinModelPortal	P94250.
ModBase	Search...
Protein family/group databases
CAZy	GH63. Glycoside Hydrolase Family 63.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBORT00000008589; EBBORP00000007919; EBBORG00000008588.
GeneID	1195218.
GenomeReviews	Gene locus BB_0381 in contig AE000783_GR.
KEGG	bbu:BB0381.
PATRIC	20557372. VBIBorBur75917_0776.
TIGR	BB_0381.
Phylogenomic databases
GeneTree	EBGT00050000007435.
HOGENOM	HBG352897.
OMA	VHSAYCI.
ProtClustDB	CLSK785733.
Enzyme and pathway databases
BioCyc	BBUR224326:BB_0381-MONOMER.
Family and domain databases
InterPro	IPR008928. 6-hairpin_glycosidase-like. IPR001661. Glyco_hydro_37. [Graphical view]
Pfam	PF01204. Trehalase. 1 hit. [Graphical view]
SUPFAM	SSF48208. Glyco_trans_6hp. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Y381_BORBU

Accession

Primary (citable) accession number: P94250
Secondary accession number(s): O50167

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	December 15, 1998
Last modified:	January 25, 2012
This is version 63 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information