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P94170 (CAH_NOSS1) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Carbonic anhydrase
EC=4.2.1.1
Alternative name(s):
Carbonate dehydratase
Gene names
Name:ecaA
Ordered Locus Names:all2929
OrganismNostoc sp. (strain PCC 7120 / UTEX 2576) [Complete proteome] [HAMAP]
Taxonomic identifier103690 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Nostoc

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reversible hydration of carbon dioxide.

Catalytic activity

H2CO3 = CO2 + H2O.

Cofactor

Zinc By similarity.

Post-translational modification

Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

Sequence similarities

Belongs to the alpha-carbonic anhydrase family.

Ontologies

Keywords
   DomainSignal
   LigandMetal-binding
Zinc
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processone-carbon metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncarbonate dehydratase activity

Inferred from electronic annotation. Source: EC

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3333Tat-type signal Potential
Chain34 – 264231Carbonic anhydrase
PRO_0000004263

Regions

Region214 – 2152Substrate binding By similarity

Sites

Metal binding1271Zinc; catalytic By similarity
Metal binding1291Zinc; catalytic By similarity
Metal binding1461Zinc; catalytic By similarity

Sequences

Sequence LengthMass (Da)Tools
P94170 [UniParc].

Last modified May 1, 1997. Version 1.
Checksum: 81C10CCD974B4172

FASTA26429,639
        10         20         30         40         50         60 
MSSTLYRRQL LKLLGMSVLG TSFSSCVTSP ARAKTVNWGY IGKVGPEHWG ELSPDFALCQ 

        70         80         90        100        110        120 
IGRKQTPIDL QIADVKDVHS SSQDLLVTNY QPTALHLINN GKTVQVNYQP GSYLKYAHQK 

       130        140        150        160        170        180 
FELLQFHFHH FSEHRVDGKL YDMELHLVHR SKSGDLAVMG IFLQAGAFNP TLQIIWDATP 

       190        200        210        220        230        240 
QNQGTDKRIE DINIDASQFL PAQHRFFTYS GSLTTPPCSE NVLWCVMATP IEASPAQIAK 

       250        260 
FSQMFPQNAR PVQPLNDRLV IEAI

« Hide

References

« Hide 'large scale' references
[1]"Identification and characterization of a gene encoding a vertebrate-type carbonic anhydrase in cyanobacteria."
Soltes-Rak E., Mulligan M.E., Coleman J.R.
J. Bacteriol. 179:769-774(1997) [PubMed: 9006032] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete genomic sequence of the filamentous nitrogen-fixing cyanobacterium Anabaena sp. strain PCC 7120."
Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M. expand/collapse author list , Takazawa M., Yamada M., Yasuda M., Tabata S.
DNA Res. 8:205-213(2001) [PubMed: 11759840] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7120 / UTEX 2576.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U72708 Genomic DNA. Translation: AAC44831.1.
BA000019 Genomic DNA. Translation: BAB74628.1.
PIRAB2172.
RefSeqNP_486969.1. NC_003272.1.

3D structure databases

ProteinModelPortalP94170.
ModBaseSearch...

Protein-protein interaction databases

STRINGP94170.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1106527.
GenomeReviewsGene locus all2929 in contig BA000019_GR.
KEGGana:all2929.
NMPDRfig|103690.1.peg.3236.
PATRIC22776154. VBINosSp37423_3537.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3338.
HOGENOMHBG717384.
OMAQFHFHAP.
ProtClustDBCLSK895842.

Enzyme and pathway databases

BioCycNSP103690:ALL2929-MONOMER.

Family and domain databases

InterProIPR001148. a_carbonic_anhydrase.
IPR023561. Carbonic_anhydrase_a-class.
IPR018338. Carbonic_anhydrase_a-class_CS.
IPR006311. TAT_signal.
[Graphical view]
Gene3DG3DSA:3.10.200.10. Euk_COanhd. 1 hit.
KOK01674.
PANTHERPTHR18952. Euk_COanhd. 1 hit.
PfamPF00194. Carb_anhydrase. 1 hit.
[Graphical view]
SMARTSM01057. Carb_anhydrase. 1 hit.
[Graphical view]
SUPFAMSSF51069. Euk_COanhd. 1 hit.
PROSITEPS00162. ALPHA_CA_1. 1 hit.
PS51144. ALPHA_CA_2. 1 hit.
PS51318. TAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAH_NOSS1
AccessionPrimary (citable) accession number: P94170
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: May 1, 1997
Last modified: January 25, 2012
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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