Reviewed, UniProtKB/Swiss-Prot P94132 (ETFD_ACIAD)

Names and origin

Protein names

Recommended name:
    Probable electron transfer flavoprotein-ubiquinone oxidoreductase
      Short name=ETF-ubiquinone oxidoreductase
      Short name=ETF-QO
    EC=1.5.5.1
Alternative name(s):
    Electron-transferring-flavoprotein dehydrogenase
      Short name=ETF dehydrogenase

Gene names

Name:	etfD
Ordered Locus Names:	ACIAD1680

Organism

Acinetobacter sp. (strain ADP1) [Complete proteome] [HAMAP]

Taxonomic identifier

62977 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Moraxellaceae › Acinetobacter

Protein attributes

Sequence length	570 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Predicted.

General annotation (Comments)

Function	Accepts electrons from ETF and reduces ubiquinone.
Catalytic activity	Reduced electron-transferring flavoprotein + ubiquinone = electron-transferring flavoprotein + ubiquinol.
Cofactor	Binds 1 4Fe-4S cluster. FAD.
Sequence similarities	Contains 1 4Fe-4S ferredoxin-type domain.

Ontologies

Keywords
Biological process	Electron transport Transport
Ligand	4Fe-4S FAD Flavoprotein Iron Iron-sulfur Metal-binding Ubiquinone
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW electron-transferring-flavoprotein dehydrogenase activity Inferred from electronic annotation. Source: EC iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 570	570	Probable electron transfer flavoprotein-ubiquinone oxidoreductase		PRO_0000200681
Regions
	Domain	530 – 559	30	4Fe-4S ferredoxin-type
	Nucleotide binding	13 – 27	15	FAD Potential
Sites
	Metal binding	515	1	Iron-sulfur (4Fe-4S) Potential
	Metal binding	539	1	Iron-sulfur (4Fe-4S) Potential
	Metal binding	542	1	Iron-sulfur (4Fe-4S) Potential
	Metal binding	545	1	Iron-sulfur (4Fe-4S) Potential

Sequences

	Sequence		Length	Mass (Da)
	P94132-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: 0107DD88E78A7DE5	FASTA	570	62,996
	10 20 30 40 50 60 MITIEREAME FDVVIVGAGP AGLSAAIKIR QLAIENNLPD LSVCVVEKGS EVGAHILSGA 70 80 90 100 110 120 VLEPRAINEL FPNWKEEGAP LNVPVTEDKT YFLMSDEKSQ EAPHWMVPKT MHNDGNYVIS 130 140 150 160 170 180 LGNVVRWLGQ KAEELEVSIF PGFAAAEILY HADGTVKGIQ TGDMGIGKDG EPTHNFAPGY 190 200 210 220 230 240 ELHAKYTLFA EGCRGHLGKR LINKFNLDQD ADPQHYGIGI KELWEIDPAK HKPGLVMHGS 250 260 270 280 290 300 GWPLSETGSS GGWWLYHAEN NQVTLGMIVD LSYENPHMFP FMEMQRWKTH PLIKQYLEGG 310 320 330 340 350 360 KRISYGARAV VKGGLNSLPK LTFPGGCLIG DDAGFLNFAK IKGSHTAMKS GMLCGEAVFE 370 380 390 400 410 420 AIARGVDKGG DLAIARVVEG EDLFDKELTT YTQKFDKSWL KEELHRSRNF GPAMHKFGLW 430 440 450 460 470 480 IGGAFNFVDQ NIFKVPFTLH DLQPDYSALK TQDQATFKPN YPKPDGKLTF DRLSSVFVSN 490 500 510 520 530 540 TVHEENQPSH LKLTDASIPV AVNLPRWDEP AQRYCPAGVY EIVDEGEGNK RFQINAANCV 550 560 570 HCKTCDIKDP SQNITWVTPE GGGGPNYPNM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"mucK, a gene in Acinetobacter calcoaceticus ADP1 (BD413), encodes the ability to grow on exogenous cis,cis-muconate as the sole carbon source." Williams P.A., Shaw L.E. J. Bacteriol. 179:5935-5942(1997) [PubMed: 9294455] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium." Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C. Nucleic Acids Res. 32:5766-5779(2004) [PubMed: 15514110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	U87258 Genomic DNA. Translation: AAC27118.1. CR543861 Genomic DNA. Translation: CAG68525.1.
RefSeq	YP_046347.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2881144.
GenomeReviews	Gene locus ACIAD1680 in contig CR543861_GR.
KEGG	aci:ACIAD1680.
NMPDR	fig|62977.3.peg.1609.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P94132.
OMA	P94132. NQNINWT.
Enzyme and pathway databases
BioCyc	ASP62977:ACIAD1680-MON.
Family and domain databases
InterPro	IPR017896. 4Fe4S_Fe-S-bd. IPR007859. ETFD_OxRdtase. IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR003042. Rng_hydrolase-like. [Graphical view]
Pfam	PF05187. ETF_QO. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00420. RNGMNOXGNASE.
PROSITE	PS51379. 4FE4S_FER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ETFD_ACIAD

Accession

Primary (citable) accession number: P94132

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	May 1, 1997
Last modified:	June 16, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)