Reviewed, UniProtKB/Swiss-Prot P94029 (MT2A_ORYSJ)

Names and origin

Protein names

Recommended name:
    Metallothionein-like protein 2A
Alternative name(s):
    Class I metallothionein-like protein 2A
    OsMT-I-2a
      Short name=OsMT2a
    OsMT2-1

Gene names

Name:	MT2A
Synonyms:	MT-2
Ordered Locus Names:	Os01g0149800, LOC_Os01g05650
ORF Names:	P0434B04.33

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	82 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Tissue specificity	Expressed in stems, leaves, rachis, inflorescences and seeds. Ref.5
Induction	By sucrose starvation, heat shock and abscisic acid (ABA). Not induced by heavy metals. Ref.1
Sequence similarities	Belongs to the metallothionein superfamily. Type 15 family.

Ontologies

Keywords
Biological process	Stress response
Ligand	Metal-binding Metal-thiolate cluster
Gene Ontology (GO)
Biological process	response to stress Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 82	82	Metallothionein-like protein 2A		PRO_0000197407

Sequences

	Sequence		Length	Mass (Da)
	P94029-1 [UniParc]. Last modified May 1, 1997. Version 1. Checksum: 8DCD62B8B6E503C4	FASTA	82	7,852
	10 20 30 40 50 60 MSCCGGNCGC GSGCQCGSGC GGCKMYPEMA EEVTTTQTVI MGVAPSKGHA EGLEAGAAAG 70 80 AGAENGCKCG DNCTCNPCNC GK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"RNA expression patterns of a type 2 metallothionein-like gene from rice." Hsieh H.M., Liu W.K., Chang A., Huang P.C. Plant Mol. Biol. 32:525-529(1996) [PubMed: 8980501] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], INDUCTION. Strain: cv. Tainung 67. Tissue: Root.
[2]	"The genome sequence and structure of rice chromosome 1." Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T. Nature 420:312-316(2002) [PubMed: 12447438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"Curated genome annotation of Oryza sativa ssp. japonica and comparative genome analysis with Arabidopsis thaliana." The rice annotation project (RAP) Genome Res. 17:175-183(2007) [PubMed: 17210932] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[5]	"Molecular analyses of the metallothionein gene family in rice (Oryza sativa L.)." Zhou G., Xu Y., Li J., Yang L., Liu J.-Y. J. Biochem. Mol. Biol. 39:595-606(2006) [PubMed: 17002881] [Abstract] Cited for: GENE FAMILY, TISSUE SPECIFICITY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U43530 mRNA. Translation: AAC49627.1. D89931 Genomic DNA. Translation: BAA14038.1. AP002540 Genomic DNA. Translation: BAB44010.1. AP008207 Genomic DNA. Translation: BAF03942.1.
PIR	T03727.
RefSeq	NP_001042028.1.
UniGene	Os.46398
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4324514.
GenomeReviews	Gene locus MT2A in contig AP008207_GR.
KEGG	osa:4324514.
NMPDR	fig|39947.1.peg.1216.
Organism-specific databases
Gramene	P94029.
Family and domain databases
InterPro	IPR000347. Metallthion_15p. [Graphical view]
Pfam	PF01439. Metallothio_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MT2A_ORYSJ

Accession

Primary (citable) accession number: P94029
Secondary accession number(s): Q0JQN6, Q7F7X9

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	May 1, 1997
Last modified:	November 24, 2009
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)