Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Dehydration-responsive element-binding protein 1B

Gene

DREB1B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates cold-inducible transcription. CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation.2 Publications

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi47 – 10458AP2/ERFPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • transcription factor activity, sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • cold acclimation Source: TAIR
  • positive regulation of transcription, DNA-templated Source: TAIR
  • response to cold Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Stress response, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Dehydration-responsive element-binding protein 1B
Short name:
Protein DREB1B
Alternative name(s):
C-repeat/dehydration-responsive element-binding factor 1
Short name:
C-repeat-binding factor 1
Short name:
CRT/DRE-binding factor 1
Gene namesi
Name:DREB1B
Synonyms:CBF1, ERF029
Ordered Locus Names:At4g25490
ORF Names:M7J2.140
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

TAIRiAT4G25490.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 213213Dehydration-responsive element-binding protein 1BPRO_0000112529Add
BLAST

Proteomic databases

PaxDbiP93835.
PRIDEiP93835.

Expressioni

Inductioni

By cold stress.1 Publication

Gene expression databases

ExpressionAtlasiP93835. baseline and differential.
GenevisibleiP93835. AT.

Interactioni

Protein-protein interaction databases

BioGridi13940. 3 interactions.
IntActiP93835. 4 interactions.
STRINGi3702.AT4G25490.1.

Structurei

3D structure databases

ProteinModelPortaliP93835.
SMRiP93835. Positions 48-103.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi32 – 4413Nuclear localization signalSequence analysisAdd
BLAST

Sequence similaritiesi

Contains 1 AP2/ERF DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IVY9. Eukaryota.
ENOG410YK37. LUCA.
HOGENOMiHOG000237624.
InParanoidiP93835.
KOiK09286.
OMAiRIPETAC.
OrthoDBiEOG09360N5C.
PhylomeDBiP93835.

Family and domain databases

Gene3Di3.30.730.10. 1 hit.
InterProiIPR001471. AP2/ERF_dom.
IPR016177. DNA-bd_dom.
[Graphical view]
PfamiPF00847. AP2. 1 hit.
[Graphical view]
PRINTSiPR00367. ETHRSPELEMNT.
SMARTiSM00380. AP2. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS51032. AP2_ERF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P93835-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSFSAFSEM FGSDYEPQGG DYCPTLATSC PKKPAGRKKF RETRHPIYRG
60 70 80 90 100
VRQRNSGKWV SEVREPNKKT RIWLGTFQTA EMAARAHDVA ALALRGRSAC
110 120 130 140 150
LNFADSAWRL RIPESTCAKD IQKAAAEAAL AFQDETCDTT TTNHGLDMEE
160 170 180 190 200
TMVEAIYTPE QSEGAFYMDE ETMFGMPTLL DNMAEGMLLP PPSVQWNHNY
210
DGEGDGDVSL WSY
Length:213
Mass (Da):23,830
Last modified:May 24, 2004 - v2
Checksum:iED1B79183C3D34C3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti143 – 1431N → D in AAC49662 (PubMed:9023378).Curated
Sequence conflicti143 – 1431N → D in AAC99369 (PubMed:9881163).Curated
Sequence conflicti143 – 1431N → D in AAV80413 (PubMed:16244146).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti127 – 1271E → K in strain: cv. Cvi-1. 1 Publication
Natural varianti178 – 1781T → S in strain: cv. Cvi-1. 1 Publication

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U77378 mRNA. Translation: AAC49662.1.
AB007788 mRNA. Translation: BAA33792.1.
AB013816 Genomic DNA. Translation: BAA33435.1.
AF076155 Genomic DNA. Translation: AAC99369.1.
AY667247 Genomic DNA. Translation: AAV80413.1.
AL022197 Genomic DNA. Translation: CAA18177.1.
AL161563 Genomic DNA. Translation: CAB81359.1.
CP002687 Genomic DNA. Translation: AEE85066.1.
PIRiJE0298.
RefSeqiNP_567721.1. NM_118681.3.
UniGeneiAt.232.

Genome annotation databases

EnsemblPlantsiAT4G25490.1; AT4G25490.1; AT4G25490.
GeneIDi828653.
GrameneiAT4G25490.1; AT4G25490.1; AT4G25490.
KEGGiath:AT4G25490.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U77378 mRNA. Translation: AAC49662.1.
AB007788 mRNA. Translation: BAA33792.1.
AB013816 Genomic DNA. Translation: BAA33435.1.
AF076155 Genomic DNA. Translation: AAC99369.1.
AY667247 Genomic DNA. Translation: AAV80413.1.
AL022197 Genomic DNA. Translation: CAA18177.1.
AL161563 Genomic DNA. Translation: CAB81359.1.
CP002687 Genomic DNA. Translation: AEE85066.1.
PIRiJE0298.
RefSeqiNP_567721.1. NM_118681.3.
UniGeneiAt.232.

3D structure databases

ProteinModelPortaliP93835.
SMRiP93835. Positions 48-103.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi13940. 3 interactions.
IntActiP93835. 4 interactions.
STRINGi3702.AT4G25490.1.

Proteomic databases

PaxDbiP93835.
PRIDEiP93835.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G25490.1; AT4G25490.1; AT4G25490.
GeneIDi828653.
GrameneiAT4G25490.1; AT4G25490.1; AT4G25490.
KEGGiath:AT4G25490.

Organism-specific databases

TAIRiAT4G25490.

Phylogenomic databases

eggNOGiENOG410IVY9. Eukaryota.
ENOG410YK37. LUCA.
HOGENOMiHOG000237624.
InParanoidiP93835.
KOiK09286.
OMAiRIPETAC.
OrthoDBiEOG09360N5C.
PhylomeDBiP93835.

Miscellaneous databases

PROiP93835.

Gene expression databases

ExpressionAtlasiP93835. baseline and differential.
GenevisibleiP93835. AT.

Family and domain databases

Gene3Di3.30.730.10. 1 hit.
InterProiIPR001471. AP2/ERF_dom.
IPR016177. DNA-bd_dom.
[Graphical view]
PfamiPF00847. AP2. 1 hit.
[Graphical view]
PRINTSiPR00367. ETHRSPELEMNT.
SMARTiSM00380. AP2. 1 hit.
[Graphical view]
SUPFAMiSSF54171. SSF54171. 1 hit.
PROSITEiPS51032. AP2_ERF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDRE1B_ARATH
AccessioniPrimary (citable) accession number: P93835
Secondary accession number(s): O65611, Q5QE71
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: May 24, 2004
Last modified: September 7, 2016
This is version 121 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.