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Protein

BTB/POZ domain-containing protein At1g04390

Gene

At1g04390

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.By similarity

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ubl conjugation pathway

Enzyme and pathway databases

UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
BTB/POZ domain-containing protein At1g04390
Gene namesi
Ordered Locus Names:At1g04390
ORF Names:F19P19.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G04390.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004085321 – 1002BTB/POZ domain-containing protein At1g04390Add BLAST1002

Proteomic databases

PaxDbiP93820.

Interactioni

Protein-protein interaction databases

BioGridi24765. 1 interactor.
STRINGi3702.AT1G04390.1.

Structurei

3D structure databases

ProteinModelPortaliP93820.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini680 – 758BTB 1PROSITE-ProRule annotationAdd BLAST79
Domaini808 – 889BTB 2PROSITE-ProRule annotationAdd BLAST82

Domaini

The BTB/POZ domain mediates the interaction with some component of ubiquitin ligase complexes.1 Publication

Sequence similaritiesi

Contains 2 BTB (POZ) domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410IHN7. Eukaryota.
ENOG410YBFM. LUCA.
InParanoidiP93820.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR000210. BTB/POZ_dom.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PfamiPF00651. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 2 hits.
SSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: P93820-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MASSKGGNTT AHINTLHHRL YHALNLGFRV CDEKEKKWKC TDIEIQRHVV
60 70 80 90 100
KSISAFLDCF SRATANNRLI KDSISDIAGA LVFILGSKNR AVVGLAANVV
110 120 130 140 150
IRLIRIVPPS ILHSYSLDLV ESLSPLLCCQ QFDVSLPCAV ALNAILVNVR
160 170 180 190 200
ETKEKEVWKI LEDEKTVVSV VGNLQIFSEG SMSVEWFQEM ALLLSTIMLK
210 220 230 240 250
WPQSRYSVWN NPALMGVLES VSQKPDMGLT VATLKLYSSL ALCGHGANEL
260 270 280 290 300
LDNGKPMLDM MISCMEESSS QNARIEGLKL AQRLATGNRE CLKMINMCSE
310 320 330 340 350
SLVKATVRTM GKWFLSSGKL ELDQMSLLVE ACKLALITRW EGQHHIYFWK
360 370 380 390 400
YRISEALLSL VVENFHSQSL DGYVSLEEEV LVAEKVLNAN FLPSLRSYVW
410 420 430 440 450
DIIGFLAAHC EEEFDSILRG DELCLNFLVT CACLSFSRSV QKGYQICQND
460 470 480 490 500
IISASHSESA SRAVLMMICS PSKYISSRAR VTLSFILEEG GEQNLNSLVN
510 520 530 540 550
FLSYIPSSGG YILPNILQTT VCLVGFACYS SIPQYASFIL RKQGLEILLS
560 570 580 590 600
FCSWYQRNWE NIGASSFAPS SQSITEKRIC CWVCTEDWDN KDAFLLYALL
610 620 630 640 650
ALAELVNHSF FGQNHAEELS MKSGNLKDRL CTTLKEIRDG TYGSGPRWYA
660 670 680 690 700
AHILSYFGYY GFEHKLGKRL MCAYEDEEYS DMRLLFASGN SASVNKVIIA
710 720 730 740 750
VRCPMLLPPK EGAHSSSTIS TEKSQRTVQE IRMSANVDIL ALVKLLEFAY
760 770 780 790 800
SGYVEVESTT LKKLKPLAKH CKAKVLLQML CRRRPKWGSS IPEIDIPLAL
810 820 830 840 850
TPKLIHFSDV ILVPKETNVA CFNCRMCSLT SPHAHSHRVI LSSGCEYLRA
860 870 880 890 900
LFRSGMQESH LDRLNVPVSW LGLTKLVSWF YSDELPKPPS GCKWNNMDTE
910 920 930 940 950
AKLDELQAYV EIYSLSEWWI MEELQNDCAH VILSCLESAR ELSIKTIELA
960 970 980 990 1000
ASFSMWKLVE AAANHAAPIY HQLRDSGELD ELDDELVNLI RTAAVQFSQQ

GG
Note: Constructed according to the conserved gene model. No experimental confirmation available.
Length:1,002
Mass (Da):112,373
Last modified:May 31, 2011 - v3
Checksum:i981A2D7A1CC5FF01
GO
Isoform 2 (identifier: P93820-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-465: Missing.

Show »
Length:537
Mass (Da):60,529
Checksum:i6E3B45995184E9AC
GO

Sequence cautioni

The sequence AAB70453 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AEE27691 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0411101 – 465Missing in isoform 2. 1 PublicationAdd BLAST465

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000104 Genomic DNA. Translation: AAB70453.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE27691.1. Sequence problems.
AK228712 mRNA. Translation: BAF00614.1.
PIRiG86175.
UniGeneiAt.42450.

Genome annotation databases

KEGGiath:AT1G04390.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Web resourcesi

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000104 Genomic DNA. Translation: AAB70453.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE27691.1. Sequence problems.
AK228712 mRNA. Translation: BAF00614.1.
PIRiG86175.
UniGeneiAt.42450.

3D structure databases

ProteinModelPortaliP93820.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi24765. 1 interactor.
STRINGi3702.AT1G04390.1.

Proteomic databases

PaxDbiP93820.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

KEGGiath:AT1G04390.

Organism-specific databases

TAIRiAT1G04390.

Phylogenomic databases

eggNOGiENOG410IHN7. Eukaryota.
ENOG410YBFM. LUCA.
InParanoidiP93820.

Enzyme and pathway databases

UniPathwayiUPA00143.

Miscellaneous databases

PROiP93820.

Family and domain databases

InterProiIPR016024. ARM-type_fold.
IPR000210. BTB/POZ_dom.
IPR011333. SKP1/BTB/POZ.
[Graphical view]
PfamiPF00651. BTB. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 2 hits.
SSF54695. SSF54695. 1 hit.
PROSITEiPS50097. BTB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY1439_ARATH
AccessioniPrimary (citable) accession number: P93820
Secondary accession number(s): F4I487, Q0WQI5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 31, 2011
Last sequence update: May 31, 2011
Last modified: November 30, 2016
This is version 82 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.